Polyhedral Oligomeric Silsesquioxanes(POSS)-based Hybrid Materials:Molecular Design,Solution *** and Biomedical Applications

作     者：Linfeng Fan Xing Wang Decheng Wu Linfeng Fan;Xing Wang;Decheng Wu

作者机构：Beijing National Laboratory for Molecular SciencesState Key Laboratory of Polymer Physics&ChemistryInstitute of ChemistryChinese Academy of SciencesBejing 100190China University of Chinese Academy of SciencesBejjing 100049China Department of Biomedical EngineeringSouthern University of Science and TechnologyShenzhenGuangdong 518055China 

基　　金：This research was supported by NSFC(51973226,21725403 and 21504096) the Youth Innovation Promotion Association CAS(No.2019031) 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2021年第39卷第3期

页      码：757-774页

摘      要：Owing to the tremendous advantages and unique well-defined nanoscale structure,polyhedral oligomeric silsesquioxanes(POSS)have received considerable interest in the design of novel organic-inorganic hybrid nanomaterials with all manner of prominent capabilities,which is rec-ognized as a new generation of promising materials for advanced applications of material sci-ence,engineering science and biomedical *** from the recent progress in combi-nation of controlled/living polymerization and emerging click chemistry,POSS-based hybrid ma-terials with ingenious design,versatile topological structure and sophisticated multifunctionality have been successfully fabricated and developed into abundant well-defined hybrid nanostruc-tures with desired physicochemical ***-made amphiphilic molecular design and nanosized hybrid architecture provide opportunities for the self-assembly of POSS-based hybrid materials with unique hierarchical morphologies in selective *** the in-depth understanding of structure-properties relationship,POSS-based hybrid materials can achieve the modulation of precise control of self-assembling process and multi-purpose applications with improved material *** this review,we summarize the recent advances of POSS-based hybrid materials in molecular design,self-assembly behavior in solutions and poten-tial biomedical applications with main concerns on drug delivery,gene therapy,bioimaging and tissue engineering ***,future directions and remaining challenges for further advance-ment of POSS-based hybrid materials are proposed and discussed.

主 题 词：POSS Hybrids Topology Self-assembly Drug delivery Bone regeneration 

学科分类：0831[工学-公安技术类] 08[工学] 0836[0836] 

核心收录：

D　O　I：10.1002/cjoc.202000536

馆 藏 号：203102701...