Designing the mechanical properties of peptide-based supramolecular hydrogels for biomedical applications

作     者：LI Ying QIN Meng CAO Yi WANG Wei 

作者机构：Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution ControlChemistry DepartmentSchool of Environmental Science & EngineeringNanjing University of Information Science & Technology National Laboratory of Solid State MicrostructureDepartment of PhysicsNanjing University 

基　　金：supported by the National Natural Science Foundation of China(Grant Nos.11304156,11334004,91127026,31170813 and 11074115) China Postdoctoral Science Foundation(Grant No.2013M531312) the Priority Academic Program Development of Jiangsu Higher Education Institutions the Program for New Century Excellent Talents in University 

出 版 物：《Science China(Physics,Mechanics & Astronomy)》 (中国科学：物理学、力学、天文学（英文版）)

年 卷 期：2014年第57卷第5期

页      码：849-858页

摘      要：Hydrogels are a class of special materials that contain a large amount of water and behave like *** materials have found broad applications in tissue engineering,cell culturing,regenerative medicine ***,the exploration of peptide-based supramolecular hydrogels has greatly expanded the repertoire of hydrogels suitable for biomedical ***,the mechanical properties of peptide-based hydrogels are intrinsically ***,it is crucial to develop methods that can improve the mechanical stability of such peptide-based *** this review,we explore the factors that determine or influence the mechanical stability of peptide-based hydrogels and summarize several key elements that may guide scientists to achieve mechanically improved *** addition,we exemplified several methods that have been successfully developed to prepare hydrogels with enhanced mechanical *** mechanically strong peptide-based hydrogels may find broad applications as novel *** is still challenging to engineer hydrogels in order to mimic the mechanical properties of biological *** hydrogel materials with optimal mechanical properties suitable for various types of biological applications will be available in the near future.

主 题 词：low molecular weight gelators (LMWG) peptide-based hydrogel hydrogelation mechanical properties (stability) modulus rheology 

学科分类：08[工学] 080502[080502] 0805[工学-能源动力学] 

核心收录：

D　O　I：10.1007/s11433-014-5427-z

馆 藏 号：203104292...