A state-of-the-art review of the fabrication and characteristics of titanium and its alloys for biomedical applications

作     者：Masoud Sarraf Erfan Rezvani Ghomi Saeid Alipour Seeram Ramakrishna Nazatul Liana Sukiman Masoud Sarraf;Erfan Rezvani Ghomi;Saeid Alipour;Seeram Ramakrishna;Nazatul Liana Sukiman

作者机构：Centre of Advanced MaterialsDepartment of Mechanical EngineeringFaculty of EngineeringUniversity of Malaya50603 Kuala LumpurMalaysia Department of Materials Science and EngineeringSharif University of TechnologyAzadi Ave.P.O.Box 11365‑9466TehranIran Center for Nanotechnology and SustainabilityDepartment of Mechanical EngineeringNational University of SingaporeSingapore 117581Singapore 

基　　金：supported by the University of Malaya(UM)Research Grant:(FRGS/1/2020/TK0/UM/02/40) 

出 版 物：《Bio-Design and Manufacturing》 (生物设计与制造（英文）)

年 卷 期：2022年第5卷第2期

页      码：371-395页

摘      要：Commercially pure titanium and titanium alloys have been among the most commonly used materials for biomedical applications since the 1950 *** to the excellent mechanical tribological properties,corrosion resistance,biocompatibility,and antibacterial properties of titanium,it is getting much attention as a biomaterial for ***,titanium promotes osseointegration without any additional adhesives by physically bonding with the living bone at the implant *** properties are crucial for producing high-strength metallic alloys for biomedical *** alloys are manufactured into the three types ofα,β,andα+β.The scientific and clinical understanding of titanium and its potential applications,especially in the biomedical field,are still in the early *** review aims to establish a credible platform for the current and future roles of titanium in *** first explore the developmental history of ***,we review the recent advancement of the utility of titanium in diverse biomedical areas,its functional properties,mechanisms of biocompatibility,host tissue responses,and various relevant antimicrobial *** research will be directed toward advanced manufacturing technologies,such as powder-based additive manufacturing,electron beam melting and laser melting deposition,as well as analyzing the effects of alloying elements on the biocompatibility,corrosion resistance,and mechanical properties of ***,the role of titania nanotubes in regenerative medicine and nanomedicine applications,such as localized drug delivery system,immunomodulatory agents,antibacterial agents,and hemocompatibility,is investigated,and the paper concludes with the future outlook of titanium alloys as biomaterials.

主 题 词：Titanium and titanium alloys Biomedical application Functional properties Biocompatibility Antibacterial activity Advanced manufacturing 

学科分类：0831[工学-公安技术类] 08[工学] 080501[080501] 0805[工学-能源动力学] 080502[080502] 

核心收录：

D　O　I：10.1007/s42242-021-00170-3

馆 藏 号：203105786...