Mechanical stimulation devices formechanobiology studies:a market,literature,and patents review

作     者：F.Melo-Fonseca O.Carvalho M.Gasik G.Miranda F.S.Silva F.Melo-Fonseca;O.Carvalho;M.Gasik;G.Miranda;F.S.Silva

作者机构：Center for MicroElectroMechanical SystemsUniversity of Minho(CMEMS-UMinho)Campus de Azurém4800-058 GuimarãesPortugal LABBELS–Associate LaboratoryBragaGuimarãesPortugal International Iberian Nanotechnology Laboratory(INL)4715-330 BragaPortugal School of Chemical EngineeringAalto University Foundation00076 EspooFinland Seqvera Ltd.HelsinkiFinland Department of Materials and Ceramic EngineeringCICECOAveiro Institute of MaterialsUniversity of Aveiro3810-193 AveiroPortugal 

基　　金：FCT(Fundação para a Ciência e a Tecnologia)through the grant SFRH/BD/141056/2018 the project PTDC/EME-EME/1442/2020 and under the national support to R&D units grant,through the reference projects UIDB/04436/2020 and UIDP/04436/2020 the scope of the project CICECO-Aveiro Institute of Materials,UIDB/50011/2020,UIDP/50011/2020&LA/P/0006/2020,financed by national funds through the FCT/MEC(PIDDAC) 

出 版 物：《Bio-Design and Manufacturing》 (生物设计与制造（英文）)

年 卷 期：2023年第6卷第3期

页      码：340-371页

摘      要：Significant advancements in various research and technological fields have contributed to remarkable findings on the physiological dynamics of the human *** closely mimic the complex physiological environment,research has moved from two-dimensional(2D)culture systems to more sophisticated three-dimensional(3D)dynamic *** bioreactors or microfluidic-based culture models,cells are typically seeded on polymeric substrates or incorporated into 3D constructs which are mechanically stimulated to investigate cell response to mechanical stresses,such as tensile or *** review focuses on the working principles of mechanical stimulation devices currently available on the market or custom-built by research groups or protected by patents and highlights the main features still open to *** are the features which could be focused on to perform,in the future,more reliable and accurate mechanobiology studies.

主 题 词：Biomaterials Polymers Actuators Mechanical stress Mechanotransduction 

学科分类：1004[医学-公共卫生预防医学类] 10[医学] 

核心收录：

D　O　I：10.1007/s42242-023-00232-8

馆 藏 号：203121259...