Towards Plant Synthetic Genomics

作     者：Yuling Jiao Ying Wang Yuling Jiao;Ying Wang

作者机构：State Key Laboratory of Protein and Plant Gene ResearchSchool of Life SciencesPeking UniversityBeijing 100871China. Peking-Tsinghua Center for Life SciencesCenter for Quantitative BiologyAcademy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China. Peking University Institute of Advanced Agricultural SciencesShandong Laboratory of Advanced Agricultural Sciences in WeifangWeifangShandong 261325China. College of Life SciencesUniversity of Chinese Academy of SciencesBeijing 100049China. 

基　　金：National Key R&D Program of China grant 2019YFA0903900 

出 版 物：《BioDesign Research》 (生物设计研究（英文）)

年 卷 期：2023年第5卷第1期

页      码：133-136页

摘      要：Rapid advances in DNA synthesis techniques have allowed the assembly and engineering of viral and microbial *** eukaryotic organisms,with their larger genomes,abundant transposons,and prevalent epigenetic regulation,present a new frontier to synthetic *** synthetic genomics have long been proposed,and exciting progress has been made using the top-down *** this perspective,we propose applying bottom-up genome synthesis in multicellular plants,starting from the model moss Physcomitrium patens,in which homologous recombination,DNA delivery,and regeneration are possible,although further optimizations are *** then discuss technical barriers,including genome assembly and plant transformation,associated with synthetic genomics in seed plants.

主 题 词：synthesis starting allowed 

学科分类：081704[081704] 07[理学] 08[工学] 0817[工学-轻工类] 070303[070303] 0703[理学-化学类] 0836[0836] 

D　O　I：10.34133/bdr.0020

馆 藏 号：203124068...