Practical and efficient synthesis of myricetin:a scalable approach

作     者：Haijuan Gu Min Yao Qi Wang Lijuan Fan Wei Zhang Fang He Runtao Li Hao Zhang 顾海娟;姚敏;王琦;樊丽娟;张伟;和芳;李润涛;张浩

作者机构：Nantong Tumor Hospital/Affiliated Tumor Hospital of Nantong UniversityNantong 226361JiangsuChina State Key Laboratory of Natural and Biomimetic DrugsSchool of Pharmaceutical SciencesPeking UniversityBeijing 100191China Beijing Chuangli Kechuang Medical Technology Development Co.Ltd.Beijing 100191China Kunming Longjin Pharmaceutical Co.Ltd.Kunming 650000YunnanChina 

基　　金：The Clinical Medicine Special Project of Nantong University for financial support(Grant No.2022JQ011) 

出 版 物：《Journal of Chinese Pharmaceutical Sciences》 (中国药学(英文版))

年 卷 期：2024年第33卷第12期

页      码：1101-1109页

摘      要：Two total synthetic routes for the preparation of myricetin were designed and *** was validated that route B presented an efficient approach to synthesizing myricetin,starting from commercially available and inexpensive *** was synthesized with an overall yield of 60%across three steps without the need of column chromatography *** successful preparation of myricetin on a 25-g scale underscored the potential of this approach.

主 题 词：Myricetin Flavonol Total synthesis Allan-Robinson reaction 

学科分类：1007[医学-药学类] 10[医学] 

核心收录：

D　O　I：10.5246/jcps.2024.12.079

馆 藏 号：203156420...