Design, Synthesis and Fungicidal Activity of Novel Strobilurin-l,2,4-Triazole Derivatives Containing Furan or Thiophene Rings

作     者：LIU Yang LIU Ming ZHANG Dongkai HUA Xuewen WANG Baolei ZHOU Sha LI Zhengming 

作者机构：State Key Laboratory of Elemento-ovganic Chemistry Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Nankai University Tianjin 300071 P. R. China 

基　　金：国家自然科学基金 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：2016年第32卷第6期

页      码：952-958页

摘      要：A series of strobilurin-l,2,4-triazole derivatives containing a furan or thiophen ring was designed andsynthesized. The structures of the compounds were characterized by 1H NMR, 13C NMR and HRMS spectra. Thebioassays indicated that the fungicidal activities of compounds 10b（EC50=14.82 mg/L） and 10c（EC50=18.72 mg/L）against Cercospora arachidicola Hori in vitro were much higher than that of Azoxystrobin as control（EC50=40.54mg/L） and the fungicidal activities of compounds 10u（EC50=8.66 rag/L） and 10n（EC50=9.89 rag/L） against Rhizotoniacerealis in vitro were higher than that of the same control（EC50=10.86 rag/L）. Compounds 10b, 10c, 1011 and 10kcould be considered as the leading compounds for further investigation.

主 题 词：Strobilurin Fungicidal activity 1,2,4-Tfiazole Azoxystrobm 

学科分类：07[理学] 

核心收录：

D　O　I：10.1007/s40242-016-6253-9

馆 藏 号：203211231...