Clinical efficacy observation of thalamic pain treated with acupuncture under the guidance of evidence-based medicine

作     者：樊小农 张雪 武连仲 王海荣 

作者机构：天津市针灸研究所国家中医药管理局针刺量效关系三级实验室国家中医药管理局脑病针刺疗法重点研究室天津市针灸学重点实验室中国天津300193 天津中医药大学第一附属医院 内蒙古包头医学院第二附属医院针灸科 

基　　金：Supported by research project of "Innovation Engineering" of The First Affiliated Hospital of Tianjin University of TCM:Academy 0804 

出 版 物：《World Journal of Acupuncture-Moxibustion》 (世界针灸杂志（英文版）)

年 卷 期：2012年第22卷第3期

页      码：1-5,17页

摘      要：Objective To study the feasibility of the crossover trial design and the minimal imbalance index random distribution method in the clinical small-sample-size randomized controlled trial（RCT） research of thalamic pain treated with acupuncture under the guidance of evidence-based medicine（EBM）.Methods The crossover trial design was *** cases with the definite diagnosis were randomized into a program-I group（6 cases,treated with acupuncture before western medicine） and a program-II group（5 cases,treated with western medicine before acupuncture） according to the minimal imbalance index *** the statistical analysis,the groups were named as an acupuncture group and a western medicine group separately,11 cases in each *** was applied to Xìmén（郄门 PC 4）,Yīnxì（阴郄 HT 6）,Xuèhǎi（血海 SP 10）,*** the control treatment,Carbamazepine was prescribed for oral *** the duration of treatment or the wash-out period was 10 *** visual analogue scale（VAS） was adopted for the efficacy *** The total effective was 100.0%（11/11） after treatment in either *** remarkably effective rates were 63.6%（7/11） and 36.4%（4/11） in the acupuncture group and the western medicine group separately,without statistically significant difference in *** The crossover trial design and the minimal imbalance index distribution method can accomplish RCT of the clinical acupuncture and moxibustion research with the small sample size *** can provide the high-quality evidences for clinical acupuncture *** therapy can achieve the same therapeutic effect as Carbamazepine,the common western medicine,and the efficacy of it is potentially superior to that of western medicine.

主 题 词：thalamic pain acupuncture therapy evidence based medicine(EBM) crossover trial design random minimal imbalance index distribution method 

学科分类：1005[医学-中医学类] 100512[100512] 10[医学] 

D　O　I：10.1016/S1003-5257(12)60033-6

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