Designer probiotics: Development and applications in gastrointestinal health

作     者：Roy D Sleator 

作者机构：Department of Biological SciencesCork Institute of Technology 

出 版 物：《World Journal of Gastrointestinal Pathophysiology》 (世界胃肠病理生理学杂志（英文版）（电子版）)

年 卷 期：2015年第6卷第3期

页      码：73-78页

摘      要：Given the increasing commercial and clinical relevance of probiotics, improving their stress tolerance profile and ability to overcome the physiochemical defences of the host is an important biological goal. Herein, I review the current state of the art in the design of engineered probiotic cultures, with a specific focus on their utility as therapeutics for the developing world; from the treatment of chronic and acute enteric infections, andtheir associated diarrhoeal complexes, to targeting HIV and application as novel mucosal vaccine delivery vehicles.

主 题 词：Gastrointestinal tract Probiotics BetL Listeria monocytogenes Bifidobacterium Lactobacillus 

学科分类：1002[医学-临床医学类] 100201[100201] 10[医学] 

D　O　I：10.4291/wjgp.v6.i3.73

馆 藏 号：203398305...