优化hCG的界值:单次测定第14天或第15天的值足以准确预测妊娠结果

作     者：Lambers M.J. van Weering H.G.I. van't Grune-wold M.S. 朱晓明 

作者机构：Department of Obstetrics Gynecology and Reproductive MedicineVUUniversity Medical Center P.O. Box 7057 1007 MB Amsterdam Netherlands 

出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)

年 卷 期：2006年第2卷第10期

页      码：22-23页

摘      要：Objective: Optimizing the cut-off level for a single serum hCG determination around day 15 after oocyte retrieval or ovulation. Study design: Retrospective data analysis. Results: 204 hCG samples >5 IU/L between March and October 1999 taken on day 14, 15 or 16 after oocyte retrieval in 204 patients undergoing IVF or ICSI were analyzed. ROC-curves and optimal cut-off levels to discriminate between viable and non-viable pregnancies were calculated for each day separately. Cut-off levels were found at 76, 142 and 223 IU/L for day 14, 15 and 16, respectively, and were verified by 487 hCG samples >5 IU/L taken between January 2000 and June 2004. Conclusions: A single serum hCG determination on day 14 or 15 is sufficient to discriminate viable pregnancies accurately from non-viable pregnancies.

主 题 词：妊娠结果 hCG 界值 取卵 体外受精 显微注射 卵母细胞 数据分析 研究设计 

学科分类：1002[医学-临床医学类] 100211[100211] 10[医学] 

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