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Design, synthesis, and antiviral properties of 2-aryl-1H- benzimidazole-4-carboxamide derivatives

Design, synthesis, and antiviral properties of 2-aryl-1H- benzimidazole-4-carboxamide derivatives

作     者:Xianjin LUO ZhonglüZHANG Yutian YANG Fei XUE Naiyun XIU Yuanbin SHE 

作者机构:School of Chemistry and Chemical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Schools of Life Science and Environmental ScienceShanghai Normal UniversityShanghai 200234China Institute of Green Chemistry and Fine ChemicalsBeijing University of TechnologyBeijing 100022China 

出 版 物:《Frontiers of Chemical Science and Engineering》 (化学科学与工程前沿(英文版))

年 卷 期:2009年第3卷第3期

页      码:305-309页

摘      要:A series of new benzimidazole derivatives were designed and *** chemical structures were testified by 1 H NMR,infrared spectroscopy(IR),mass spectrography(MS),and elemental *** potent antiviral properties indicated the prospect of new *** 13,16,18,19,21,22,and 23 were identified as novel antivirus with much better selective activity and inhibitory activity than the comparable ribavirin against Coxsackie virus B_(3) in VERO cells.

主 题 词:benzimidazole coxsackie virus B_(3) antiviral properties 

学科分类:081704[081704] 07[理学] 08[工学] 0817[工学-轻工类] 070303[070303] 0703[理学-化学类] 

核心收录:

D O I:10.1007/s11705-009-0021-z

馆 藏 号:203415453...

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