A generalized approach for protein design based on the relative entropy

作     者：WANGYihua WANGBaohan LIUYun CHENWeizu WANGCunxin 

作者机构：CollegeofLifeScienceandBioengineeringBeijingUniversityofTechnologyBeijing100022China InstituteofBiophysics(IBP)ChineseAcademyofSciencesBeijing100101China 

基　　金：National Natural Science Foundation of China, NSFC, (10174005, 30170230) Natural Science Foundation of Beijing Municipality, (5032002) 

出 版 物：《Chinese Science Bulletin》 (中国科学通报)

年 卷 期：2004年第49卷第5期

页      码：426-431页

摘      要：In the present study, we have developed the method brought forward recently for protein design based on the relative entropy. The new approach can be used in more common situation other than the special limits in the anterior method. The results indicate that our generalized method has increased the prediction precision for protein sequence and will be in favor of the study for protein design.

主 题 词：蛋白质设计 相对熵 逆蛋白展开 分子生物学 

学科分类：081703[081703] 08[工学] 0817[工学-轻工类] 0836[0836] 

核心收录：

D　O　I：10.1007/BF02900958

馆 藏 号：203418180...