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Design, methodology, and preliminary results of the follow-up of a population-based cohort study in rural area of northern China:Handan Eye Study

Design, methodology, and preliminary results of the follow-up of a population-based cohort study in rural area of northern China:Handan Eye Study

作     者:Kai Cao Jie Hao Ye Zhang Ai-Lian Hu Xiao-Hui Yang Si-Zhen Li Bing-Song Wang Qing Zhang Jian-Ping Hu Cai-Xia Lin Mayinuer Yusufu Ning-Li Wang  Cao Kai;Hao Jie;Zhang Ye;Hu Ai-Lian;Yang Xiao-Hui;Li Si-Zhen;Wang Bing-Song;Zhang Qing;Hu Jian-Ping;Lin Cai-Xia;Yusufu Mayinuer;Wang Ning-Li;the Handan Eye Study Group

作者机构:Beijing Institute of Ophthalmology Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing 100730 China Clinical Research Center Beijing Institute of Ophthalmology Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing 100730 China Beijing Tongren Eye Center Beijing Tongren Hospital Capital Medical University Beijing 100730 China Nanjing Aier Eye Hospital Nanjing Jiangsu 210000 China the Handan Eye Study Group 

基  金:supported by the grants from the Ministry of Science and Technology of China from the Key Technologies R&D Program 

出 版 物:《Chinese Medical Journal》 (中华医学杂志(英文版))

年 卷 期:2019年第132卷第18期

页      码:2157-2167页

摘      要:Background:Handan Eye Study (HES),a large population-based cohort study in rural area of northern China,was one of the few studies focusing on the major eye diseases of rural Chinese *** aim of this study was to introduce the design,methodology and to assess the data quality of the follow-up phase of ***:All participants were recruited in Yongnian county of Handan city between 2012 and *** outcomes were measured by visual quality scales and ocular *** performed the Chi-square test to make comparison of categorical data among groups,One-way analysis of variance and Kruskal-Wallis test was applied to make comparison of continuous data among groups,a post-hoc test was done to make further pairwise ***-class correlation coefficients (ICCs) and Kappa coefficients were used to evaluate the consistency between different *** regression was used to explore the influence factors of death,odds ratio (OR) and 95% confidence interval (CI) were used to estimate the effect size of each influence ***:The follow-up rate was 85.3%.Subjects were classified into three groups:the follow-up group (n =5394),the loss to follow-up group (n =929),and the dead group (n =507),comparison of their baseline information was *** with the other two groups,age of the dead group (66.52 ± 10.31 years) was the oldest (Z =651.293,P < 0.001),male proportion was the highest (59.0 %)(x2 =42.351,P < 0.001),only 65.9 % of the dead finished middle school education (Z =205.354,P < 0.001).The marriage percentage,body mass index (BMI),best-corrected visual acuity (BCVA),and intra-ocular pressure of the dead group was the lowest *** equivalent error (SER) of the dead group was the ***,history of smoking,hypertension,diabetes,and heart disease were more common in the dead *** analysis showed that age (OR =1.901,95% CI:1.074-1.108),gender (OR =0.317,95% CI:0.224-0.448),and BCVA (OR =0.282,95%

主 题 词:Cohort study Rural population Methodology Follow-up Bias 

学科分类:10[医学] 

核心收录:

D O I:10.1097/CM9.0000000000000418

馆 藏 号:203727179...

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