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Evaluation of L929 cell morphology on anthocyanin-containing gelatin-based hydrogel for early detection of infection

Evaluation of L929 cell morphology on anthocyanin-containing gelatin-based hydrogel for early detection of infection

作     者:Ghazal Shineh Soheila S.Kordestani Mohammadreza Tahriri Lobat Tayebi 

作者机构:Biomaterials DepartmentFaculty of Biomedical EngineeringAmirkabir University of TechnologyTehranIran Marquette University School of DentistryMilwaukeeWI 53233USA 

出 版 物:《Bio-Design and Manufacturing》 (生物设计与制造(英文))

年 卷 期:2019年第2卷第3期

页      码:181-186页

摘      要:Wounds heal through a complex process including four *** interruption or interference in healing process can prevent wound *** is one of the most common complications preventing wounds from *** this study,we investigated the fibroblast cell morphology and behavior of a gelatin-based hydrogel containing anthocyanin to determine whether it can be used for early detection of *** experimental results ascertained that 6 h after culturing the fibroblasts,they could be well attached to the surface of the hydrogel,and 48 h after seeding,they were spread over the surface and connected with each *** the addition of a low dose of anthocyanin,the vitality of the cell increased,and the results of the ATR-FTIR analysis showed that anthocyanin could eliminate remaining glutaraldehyde free *** also could change its color after the addition of bacterial ***,hydrogels containing black carrot anthocyanin may be a potential therapeutic and diagnostic strategy to promote wound healing and early detection of infection.

主 题 词:Wound healing Hydrogel Gelatin Infection Anthocyanin pH 

学科分类:081704[081704] 07[理学] 08[工学] 0817[工学-轻工类] 070305[070305] 080501[080501] 0805[工学-能源动力学] 0703[理学-化学类] 

核心收录:

D O I:10.1007/s42242-019-00047-6

馆 藏 号:203727365...

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