孕前感染鼠弓形体与孕期胎死宫内的关系

作     者：Chen K.T. Eskild A. Bresnahan M. 高雪莲 

作者机构：Department of Obstetrics and Gynecology and Epidemiology Columbia University 722 West 168th St New York NY 10032 United States Dr 

出 版 物：《世界核心医学期刊文摘（妇产科学分册）》 (Core Journal in Obstetrics/Gynecology)

年 卷 期：2005年第1卷第12期

页      码：9-10页

摘      要：Objective: The purpose of this study was to assess the association between previous maternal Toxoplasma gondii (T gondii) infection and risk of fetal death. Study design: This was a population-based prospective cohort of 29,912 pregnant women without acute T gondii infection in Norway. Results: In the study population, 2937 (9.8% ) women had evidence of previous maternal T gondii infection, and 299 (1.0% ) had fetal deaths. We found no association between previous T gondii infection and risk of fetal death at ≥ 20 weeks of gestation. We did find a trend for an increased risk of fetal death at ≥ 16 and < 20 weeks of gestation. However, we noted no association between previous T gondii infection and risk of fetal death at all birth weight categories (≥ 1000, ≥ 500 and <1000, and < 500 g). Conclusion: These data do not indicate an increased risk of fetal death at ≥ 20 weeks of gestation in women with previous maternal T gondii infection.

主 题 词：胎死宫内 鼠弓形体 研究人群 前瞻性队列研究 研究设计 

学科分类：1002[医学-临床医学类] 100211[100211] 10[医学] 

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