圆锥角膜患者的生活质量

作     者：Kymes S.M. Walline J.J. Zadnik K. Gordon M.O. 秦雪娇 

作者机构：Ohio State Univ. Coll. of Optometry Columbus OH United States Dr. 

出 版 物：《世界核心医学期刊文摘（眼科学分册）》 (Digest of the World Core Medical Journals:Ophthalmology)

年 卷 期：2005年第1卷第4期

页      码：11-12页

摘      要：Purpose Keratoconus is a chronic, noninflammatory disease of the cornea with onset in early adulthood. As these years are important to financial and social health, keratoconus may have more severe impact on quality of life than would be expected given its clinical severity. We examined the vision- related quality of life of patients in the Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study. Design Crosssectional study. Methods The National Eye Institute- Visual Function Questionnaire (NEI- VFQ) was administered to 1166 CLEK Study patients at their first annual follow- up examination. Associations between clinical and demographic factors and NEI- VFQ scale scores were evaluated. Results Binocular entrance visual acuity worse than 20/40 was associated with lower quality of life scores on all scales except General Health and Ocular Pain. A steep keratometric reading (average of both eyes)>52 diopters (D) was associated with lower scores on the Mental Health, Role Difficulty, Driving, Dependency, and Ocular Pain scales. Scores for CLEK patients on all scales were between patients with category 3 and category 4 agerelated macular degeneration (AMD) except General Health, which was better than AMD patients, and Ocular Pain, which was worse than AMD patients. Conclusions Keratoconus is a disease of relatively low prevalence that rarely results in blindness, but because it affects young adults, the magnitude of its public health impact is disproportionate to its prevalence and clinical severity.

主 题 词：圆锥角膜 生活质量 角膜疾病 角膜曲率计 双眼视力 总体健康状况 老年性黄斑变性 临床危害 眼科研究所 横断面设计 

学科分类：1002[医学-临床医学类] 100212[100212] 10[医学] 

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