Can the venerated silk be the next generation nanobiomaterialfor biomedical device designing, regenerative medicine and drugdelivery? Prospects and hitches

作     者：Rocktotpal Konwarh 

作者机构：Department of BiotechnologyAddis Ababa Science and Technology University16417 Akaki KalityAddis AbabaEthiopia Centre of ExcellenceNanotechnologyAddis Ababa Science and Technology University16417 Akaki KalityAddis AbabaEthiopia 

基　　金：I would like to offer a note of gratitude to Dr. Biman B. Mandal  IIT Guwahati  India  for introducing me to the awe-inspiring niche of silk-bioengineering 

出 版 物：《Bio-Design and Manufacturing》 (生物设计与制造（英文）)

年 卷 期：2019年第2卷第4期

页      码：278-286页

摘      要：Of late, the relevance of silk in a myriad of material science and biotechnological realms has been realized, as attested by the incessantly clambering number of reports and patents in the scienti fic repositories. The write-up is geared off with a scrutiny into the pertinence of the basic nano-structural features of silk, christened as the ‘queen of textile’ for exemplary bioengi- neering applications including designing and fabrication of devices for micro fluidics, opto fluidics, chemo/bio sensing, etc. Then, the major thrust of this short review is directed towards comprehending the prospects of using silk-based biomaterials (e.g. sca ffolds, electrospun membranes, films, hydrogels, bioinks) for tissue engineering and regenerative medicine as well as targeted delivery of various biomolecular cargoes/therapeutic agents, etc., as vouched by few avant-garde endeavours of the recent years. The write-up is entwined with a discussion on the various factors that could plausibly hinder the realization of silk as the next-generation nanobiomaterial, suggestions for some approaches to dodge and deal with the practical snags and what lies ahead!

主 题 词：Drug delivery Microfluidics Nanobiomaterial Regenerative medicine Silk Tissue engineering 

学科分类：0907[农学-草药学] 08[工学] 0829[工学-安全科学与工程类] 09[农学] 

核心收录：

D　O　I：10.1007/s42242-019-00052-9

馆 藏 号：203819956...