Synchronized Anti-Phase and In-Phase Oscillations of Intracellular Calcium Ions in Two Coupled Hepatocytes System

作     者：申传胜 陈含爽 张季谦 

作者机构：Department of Educational Technology Anqing Teachers College Anqing 246011 College of Physics and Electronic Information Anhui Normal University Wuhu 241000 

基　　金：Educational Commission of Anhui Province of China under Grant No KJ2007A079 Research Fund for Young Teachers in Colleges of Anhui Province under Grant No 2007jql118 Research Fund of Anhui Normal University under Grant No 2006xzx09 安徽师范大学优秀创新团队建设计划 

出 版 物：《Chinese Physics Letters》 (中国物理快报（英文版）)

年 卷 期：2008年第25卷第3期

页      码：870-873页

摘      要：We study the dynamic behaviour of two intracellufar calcium oscillators that are coupled through gap junctions both to Ca^2＋ and inositol（1,4,5）-trisphosphate （IP3）. It is found that synchronized anti-phase and in-phase oscillations of cytoplasmic cadcium coexist in parameters space. Especially, synchronized anti-phase oscillations only occur near the onset of a Hopf bifurcation point when the velocity of IP3 synthesis is increased. In addition, two kinds of coupling effects, i.e., the diffusions of Ca^2＋ and IP3 among cells on synchronous behaviour, are considered. We fnd that small coupling of Ca^2＋ and large coupling of IP3 facilitate the emergence of synchronized anti-phase oscillations. However, the result is contrary for the synchronized in-phase case. Our findings may provide a qualitative understanding about the mechanism of synchronous behaviour of intercellular calcium signalling.

主 题 词：supernova explosion proto-neutron star shock wave 

学科分类：1002[医学-临床医学类] 100201[100201] 10[医学] 

核心收录：

D　O　I：10.1088/0256-307X/25/3/018

馆 藏 号：203824925...