Peptoid-based hierarchically-structured biomimetic nanomaterials: Synthesis, characterization and applications

作     者：Jianli Liu Bin Cai Lifeng Cui Chun-Long Chen 刘建丽;蔡彬;崔立峰;陈春龙

作者机构：School of Materials Science and EngineeringDongguan University of TechnologyDongguan 523808China Physical Sciences DivisionPhysical and Computational Sciences DirectoratePacific Northwest National LaboratoryRichland WA 99352USA 

基　　金：supported by the Startup Research Fund of Dongguan University of Technology(KCYKYQD2017015) the US Department of Energy,Office of Science,Office of Basic Energy Sciences,as part of the Energy Frontier Research Centers program:CSSAS—The Center for the Science of Synthesis Across Scales(DESC0019288) 

出 版 物：《Science China Materials》 (中国科学（材料科学（英文版）)

年 卷 期：2020年第63卷第7期

页      码：1099-1112页

摘      要：Peptoids(or poly-N-substituted glycines)are a promising class of bioinspired sequence-defined polymers due to their highly efficient synthesis,high chemical stability,enzyme hydrolysis resistance,and *** tuning the side chain chemistry of peptoids,it allows for precise control over sequences and achieving a large side-chain *** to these unique features,in the last several years,many amphiphilic peptoids were designed as highly tunable building blocks for the preparation of biomimetic nanomaterials with well-defined hierarchical structures and desired ***,we provide an overview of the recent achievements in this area by dividing them into the following three ***,mica-and silica-templated peptoid selfassembly are *** presence of inorganic substrates provides the guarantee of investigating their selfassembly mechanisms and interactions between peptoids and substrates using nanoscale characterization techniques,particularly in situ atomic force microscopy(AFM)and AFMbased dynamic force spectroscopy(AFM-DFS).Second,solution-phase self-assembly of peptoids into nanotubes and nanosheets is presented,as well as their self-repair ***,the applications of peptoid-based nanomaterials are outlined,including the construction of catalytic nanomaterials as a template and cytosolic delivery as cargoes.

主 题 词：peptoid self-assembly biomimetic nanomaterial nanoscale characterization assembly mechanism 

学科分类：07[理学] 070205[070205] 08[工学] 080501[080501] 0805[工学-能源动力学] 0702[理学-物理学类] 

核心收录：

D　O　I：10.1007/s40843-020-1296-8

馆 藏 号：203942455...