摘要：在当代教育中,专业知识与思政教育逐渐形成了有机的融合。本文以Diels-Alder反应为例,探讨了如何巧妙地融合思政元素进有机化学教学。通过这种教学设计,学生不仅深入掌握了化学原理,更领会到创新、合作和责任的核心价值。这种整合方式为高等教育提供了新的视角,着重培养学生的专业知识与科学素养,同时也涵盖了对国家科研贡献的简要认识。

摘要：文章设计了酸催化和碱催化两种不同的方法,以2-吲哚酮和靛红为原料经羟醛缩合反应合成异靛蓝,将羟醛缩合反应引入本科综合有机化学实验。酸催化方法以冰乙酸为溶剂,浓盐酸作催化剂,在回流条件下合成异靛蓝。碱催化方法以甲醇为溶剂,氢氧化钠为催化剂合成β-羟基酮,然后在稀盐酸作用下脱水制备异靛蓝,最终产物经核磁共振和红外光谱确认结构。通过该实验,让学生掌握了典型的有机化合物合成、分离和结构鉴定技术,加深了学生对有机化学反应机理等理论知识的理解和运用,激发了学生科研兴趣。

摘要：将吉非替尼药物合成路线中醛基转变为氰基的方法探讨作为综合实验,以5-(3-氯丙氧基)-4-甲氧基-2-硝基苯甲醛为原料,经亲核加成、质子迁移脱水反应、乙酰化反应和顺式消除乙酸等反应,成功制备了5-(3-氯丙氧基)-4-甲氧基-2-硝基苯腈。本实验综合运用了基础实验操作、有机合成和结构鉴定等操作单元,加强了学生对有机化学理论知识的理解,培养和激发了学生们对科学研究的兴趣和探索精神。The method of converting aldehyde groups to cyanide groups in the synthesis route of gefitinib was explored as a comprehensive experiment. Using 5-(3-chloropropoxy)-4-methoxy-2-nitrobenzaldehyde as the raw material, 5-(3-chloropropoxy)-4-methoxy-2-nitronitrile was successfully prepared through nucleophilic addition, proton transfer dehydration reaction, acetylation reaction, and cis elimination of acetic acid reaction. This experiment comprehensively utilized basic experimental operations, organic synthesis, and structural identification units to enhance students’ understanding of organic chemistry theory, cultivate and stimulate their interest and exploratory spirit in scientific research.

摘要：随着信息技术的飞速发展和智慧教育的深入推广,教育领域正经历着前所未有的变革。《工程制图与CAD》作为工科专业的重要基础课程,其教学改革与创新显得尤为重要。本文旨在智慧教育背景下,以“面的投影”为例探讨《工程制图与CAD》实现以学生发展为中心的教学新途径,同时也为其他类似课程的智慧教学模式提供借鉴。With the rapid development of information technology and the in-depth promotion of intelligent education, the field of education is experiencing unprecedented changes. As an important basic course for engineering majors, the teaching reform and innovation of Engineering Drawing and CAD is particularly important. The purpose of this paper is to explore new ways to realize student development-centered teaching of Engineering Drawing and CAD in the context of intelligent education, taking “face projection” as an example, and also to provide a reference for other similar courses’ intelligent teaching modes.

摘要：设计了荧光和羟基修饰聚天冬氨酸的制备、表征和阻垢性能的综合实验。首先合成了水溶性荧光物质和聚琥珀酰亚胺(PSI),然后用该荧光物质和乙醇胺修饰PSI并碱性水解,获得目标阻垢剂。用1H NMR、凝胶渗透色谱和荧光分光光度计表征该阻垢剂,并通过静态阻垢试验测试该阻垢剂的阻垢性能。本实验融合了高分子化学、有机化学和分析化学内容,体现了“合成–表征–分析”的科学研究过程,强调了“物质–结构–性能”的科研思维模式,可以培养学生的实验素养和科研能力。