摘要：利用Solid Works软件建立Delta并联机器人三维模型,将Solid Works三维设计软件中建立的模型导入ANSYS中,结合实际工况对Delta并联机器人主动臂进行静力学分析和模态分析。得到主动臂在极限工况下的变形量和固有频率及对应的1到5阶模态振型。为进一步优化改进Delta并联机器人主动臂的结构提供理论依据。

摘要：为尽快制定附着式升降脚手架设计标准和安全规程,以甘肃建投七建集团建筑工地附着式升降脚手架为研究对象,利用ANSYS建立附着式升降脚手架的有限元模型,对附着式升降脚手架在工作和提升两种工况条件下进行模态分析。对比不同工况对附着式升降脚手架固有频率和振型的影响,为下一步研究奠定基础。

摘要：Nucleocapsid(N) protein plays crucial roles in the life cycle of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2), including the formation of ribonucleoprotein(RNP) complex with the viral *** we reported the crystal structures of the N-terminal domain(NTD) and C-terminal domain(CTD) of the N protein and an NTD-RNA complex. Our structures reveal a unique tetramer organization of NTD and identify a distinct RNA binding mode in the NTD-RNA complex, which could contribute to the formation of the RNP complex. We also screened small molecule inhibitors of N-NTD and N-CTD and discovered that ceftriaxone sodium, an antibiotic, can block the binding of RNA to NTD and inhibit the formation of the RNP complex. These results together could facilitate the further research of antiviral drug design targeting N protein.