摘要：[Objective] This study aimed to investigate the effects of cigarette auxiliary material parameters on release amounts of tar, CO and free radicals in cigarette mainstream smoke. [Method] The effects of cigarette paper air-permeability, cigarette paper gram weight, filter rod pressure drop and filter tip ventilating strength parameters on the release amounts of tar, CO and free radicals in cigarette mainstream smoke were investigated by single factor experiment and orthogonal experiment. [Result] The cigarette paper air-permeability, filter rod pressure drop and filter tip ventilating strength showed significantly negative correlation with the release amounts of tar, CO and free radicals in cigarette mainstream smoke, to be specific, the cigarette paper air-permeability showed the greatest effect on the release amounts of tar and CO, filter tip ventilating strength showed the greatest effect on the release amounts of gaseous-phase free radicals and particulate-phase free radicals, while cigarette paper gram weight showed relatively slight effect on the release amounts of tar, CO and free radicals. Within the orthogonal experimental range, the optimal program is identified as cigarette paper airpermeability of 70 CU, filter rod pressure drop of 4500 Pa/unit, and filter tip ventilating strength of 60 CU. Compared to the results without optimization, the release amounts of tar, CO and free radicals after optimization were all reduced. [Conclusion] This study laid the foundation for the research of cigarette tar reduction and harm reduction.