摘要：X射线计算机断层扫描技术(X-ray computed tomography,CT)是目前临床医学诊断中最为重要的工具之一.临床使用的CT造影剂主要是一些有机碘类小分子,但是这类小分子造影能力有限、体内循环时间短,极大地限制了CT成像技术在疾病诊断中的应用.相比之下,CT成像纳米探针不仅极大地提升了造影能力,同时具有更好的生物相容性和更长的体内循环时间.更重要的是,其表面易修饰特性有助于多功能成像探针的构建.本文针对近年来CT成像纳米探针的设计及应用进行了简要介绍,并展望了其未来的发展方向.

摘要：Antibacterial nanoagents with broad-spectrum antibacterial activities have emerged as an evolution of ***,their bacteria-capturing capability and bacteria-killing efficiency remain insufficient for commercial *** by the hunting behavior of spiders,here,a novel spiderweb-like nanoagent based on silver-adenine nanowires is designed to achieve high-efficiency capture and killing of *** virtue of the initiative bacteriacapturing functionality,this spiderweb-like nanoagent could effectively attract and trap bacteria through electrostatic interaction and its reticular morphology ***,its synergetic antibacterial mechanism combining physical membranolysis with reactive oxygen species(ROS)release allows such nanoagent to harvest a promoted bactericidal ***,the woundplast employing the spiderweblike nanoagent exhibits a superior antibacterial efficacy against drug-resistant Gram-negative Escherichia coli and Gram-positive methicillin-resistant Staphylococcus aureus compared with commercially available *** work may pave a new way for rational design of new generation bactericidal agents facing the future super-bacteria booming.

摘要：： Ｌ Ｂ 膜作为模板可诱导晶体取向成核和外延生长，生成的晶体材料具有独特的微观结构和优异的物理化学性能。这种方法对于生物矿化现象的研究以及新颖材料合成策略的设计等方面具有重要的启示意义。本文从 Ｌ Ｂ 膜诱导晶体取向生长的机理及利用等方面综述了该领域研究的最新进展。

摘要：设计和可控构筑具有核壳结构的复合纳米材料是最近几年材料科学前沿的一个日益重要的研究领域.本文综述了无机-无机核壳结构复合材料的制备及其应用.

摘要：Theranostic nanoprobes can potentially integrate imaging and therapeutic capabilities into a single platform,offering a new personalized cancer diagnostic ***,there is a growing concern that their clinical application is not safe,particularly due to metal-containing elements,such as the gadolinium used in magnetic resonance imaging(MRI).We demonstrate for the first time that the photothermal melting of the DNA duplex helix was a reliable and versatile strategy that enables the on-demand degradation of the gadolinium-containing MRI reporter gene from polydopamine(PDA)-based theranostic *** combination of chemotherapy(doxorubicin)and photothermal therapy,which leads to the enhanced anti-tumor *** vivo MRI tracking reveals that renal filtration was able to rapidly clear the free gadolinium-containing MRI reporter from the mice *** results in a decrease in the long-term toxic effect of theranostic MRI *** findings may pave the way to address toxicity issues of the theranostic nanoprobes.