摘要：Quickly getting back the synchronism of a disturbed interconnected multi-area power system due to variations in loading condition is recognized as prominent issue related to automatic generation control(AGC).In this regard,AGC system based on fuzzy logic,i.e.,so-called FLAGC can introduce an effectual performance to suppress the dynamic oscillations of tie-line power exchanges and frequency in multi-area interconnected power *** from that,simultaneous coordination scheme based on particle swarm optimization(PSO)along with real coded genetic algorithm(RCGA)is suggested to coordinate FLAGCs of the all *** clarify the high efficiency of aforementioned strategy,two different interconnected multi-area power systems,i.e.,three-area hydro-thermal power system and five-area thermal power system have been taken into account for relevant *** potency of this strategy has been thoroughly dealt with by considering the step load perturbation(SLP)in both the under study power *** sum up,the simulation results have plainly revealed dynamic performance of FLAGC as compared with conventional AGC(CAGC)in each power system in order to damp out the power system oscillations.

摘要：In the era of burgeoning breakthroughs around medical and biomedical technologies,personalizing our medicine still sounds like a dream yet to be *** cancer as an example,while the pool of anti-cancer therapeutic agents is tremendously large,pinpointing a drug or a combination of drugs that would always work out well for a given patient,remains quite impossible—in fact,we are not even close to this ideal *** an incapability,of course,originates primarily from the overly complex,volumetrically structured and dynamic microenvironments in a patient’s tumor,meaning that the same tumor as seen on Day 1 might be entirely different than when seen again a month later.

摘要：何谓打摩最近我在杂志上看到了三诺的音箱打摩大赛的广告，能简单介绍下什么是打摩吗？

摘要：Drug resistance is a great challenge in cancer therapy using chemotherapeutic agents. Administration of these drugs with siRNA is an efficacious strategy in this battle. Here, the present study tried to incorporate siRNA and paclitaxel(PTX) simultaneously into a novel nanocarrier. The selectivity of carrier to target cancer tissues was optimized through conjugation of folic acid(FA) and glucose(Glu) onto its surface. The structure of nanocarrier was formed from ternary magnetic copolymers based on FeCopolyethyleneimine(FeCo-PEI) nanoparticles and polylactic acid-polyethylene glycol(PLA-PEG) gene delivery system. Biocompatibility of FeCo-PEI-PLA-PEG-FA(NPsA), FeCo-PEI-PLA-PEG-Glu(NPsB) and FeCo-PEI-PLA-PEG-FA/Glu(NPsAB) nanoparticles and also influence of PTX-loaded nanoparticles on in vitro cytotoxicity were examined using MTT assay. Besides, siRNA-FAM internalization was investigated by fluorescence microscopy. The results showed the blank nanoparticles were significantly less cytotoxic at various concentrations. Meanwhile, siRNA-FAM/PTX encapsulated nanoparticles exhibited significant anticancer activity against MCF-7 and BT-474 cell lines. NPsAB/siRNA/PTX nanoparticles showed greater effects on MCF-7 and BT-474 cells viability than NPsA/siRNA/PTX and NPsB/siRNA/***, they induced significantly higher anticancer effects on cancer cells compared with NPsA/siRNA/PTX and NPsB/siRNA/PTX due to their multi-targeted properties using FA and Glu. We concluded that NPsAB nanoparticles have a great potential for co-delivery of both drugs and genes for use in gene therapy and chemotherapy.

摘要：Brain tumors’severity ranges from benign to highly aggressive and *** tools can assist in understanding the pathophysiology of these tumors from outside the body and facilitate development of suitable antitumoral ***,we first describe the physiology and cellular composition of brain ***,we discuss the development of threedimensional tissue models utilizing brain tumor *** particular,we highlight the role of hydrogels in providing a biomimetic support for the cells to grow into defined *** technologies,such as electrospinning and bioprinting,and advanced cellular models aim to mimic the extracellular matrix and natural cellular localization in engineered tumor ***,we review current applications and prospects of hydrogels for therapeutic purposes,such as drug delivery and co-administration with other *** further development,hydrogels can serve as a reliable option for in vitro modeling and treatment of brain tumors for translational medicine.

摘要：Flexible risers are crucial pieces of equipment for moving output fluids from wells to platforms during the extraction of oil and gas from deepsea *** of the causes of collapse in these pipes is the high hydrostatic pressure applied to risers in deep *** innermost layer of a riser,known as the carcass layer,plays a critical role in resistance to external *** this study,we investigated the collapse(nonlinear buckling)of a riser under external pressure,and a novel design based on the structure of a beetle’s exoskeleton was used to increase the load capacity of the carcass *** type of beetle skeleton is constructed in such a way that it creates strong connections among the various parts of the external skeleton to considerably enhance strength against external pressure while allowing necessary *** assess the performance of the design in comparison with the original design,we examined the nonlinear buckling of the new structure under external *** genetic algorithm optimization,design parameters were obtained,and the maximum strength before collapse was *** show that the critical pressure in the new design substantially increases relative to that in the original design.

摘要：Empowering the value realization of ecological products with a digital economy is an important path for achieving the transformation of“two mountains”and the construction of ecological *** on the panel data of 30 provinces in China from 2011 to 2022,a fixed-effects model was used to empirically test the impact,heterogeneity and mechanism of the effects of the digital economy on the value realization of ecological *** analysis revealed three key findings.(1)The digital economy has a significant driving effect on improving the ability to realize the value of ecological products,and this effect is still applicable in a variety of robustness tests such as shrinking the years,replacing explanatory variables,and endogeneity tests.(2)The rise of the digital economy affects the value realization of ecological products to different degrees in different regions,especially in the eastern region,while the effect in the central region is not obvious.(3)The analysis of mechanistic variables indicated that the digital economy has an impact on the value realization of ecological products through the development of green finance and government ***,the government should design differentiated and multi-level support policies for the realization of ecological product value according to the heterogeneity of natural resources,ecological potential and the levels of digital economy development in different regions,and it should strengthen the control of non-environmental protection behaviors of the *** should accelerate the digital transformation of the entire production,distribution,circulation and consumption chain of ecological products,and actively develop financial products and services that meet the characteristics and needs of ecological products.

摘要：早在1999年的第一季度，微软下属著名的Digital Anvil小组就宣称要在1999年底正式发行这款令人瞩目的主视角空战游戏——《星际游骑兵》(Starlancer)。Digital Anvil小组在游戏界可是大名鼎鼎，4名成员来自著名的Origin公司。而《星际游骑兵》的主设计师就是Erin Roberts，他同时也是《银河私掠者Ⅱ》(PrivateerⅡ)的设计师。

摘要：ali Pashang ，自由摄影师，很早便对摄影充满热爱。他独特的远见和捕捉瞬间的能力，帮助他不断地创造了许多非凡的影象。他的职业生涯包括插花和设计。他一直在探索创造栩栩如生、清晰而前所未见的照片的可能性。他主要的摄影主题是动物和风景。最近，ali一直在探索摄影的其他途径，并成功地将他的照片变成了艺术。

摘要：In this paper, a hybrid neural-genetic fuzzy system is proposed to control the flow and height of water in the reservoirs of water transfer networks. These controls will avoid probable water wastes in the reservoirs and pressure drops in water distribution networks. The proposed approach combines the artificial neural network, genetic algorithm, and fuzzy inference system to improve the performance of the supervisory control and data acquisition stations through a new control philosophy for instruments and control valves in the reservoirs of the water transfer networks. First, a multi-core artificial neural network model, including a multi-layer perceptron and radial based function, is proposed to forecast the daily consumption of the water in a reservoir. A genetic algorithm is proposed to optimize the parameters of the artificial neural networks. Then, the online height of water in the reservoir and the output of artificial neural networks are used as inputs of a fuzzy inference system to estimate the flow rate of the reservoir inlet. Finally, the estimated inlet flow is translated into the input valve position using a transform control unit supported by a nonlinear autoregressive exogenous model. The proposed approach is applied in the Tehran water transfer network. The results of this study show that the usage of the proposed approach significantly reduces the deviation of the reservoir height from the desired levels.