摘要：In this pa.er the design of a.novel modula. hydra.lic/pneuma.ic a.tua.ed tele-robotic system a.d a.new infra.tructure for MRI-guided intervention for closed-bore MRI-guided neurosurgery a.e presented. Ca.dida.e neurosurgica. procedures ena.led by this system would include therma. a.la.ion, ra.iofrequency a.la.ion, deep bra.n stimula.ors, a.d ta.geted drug delivery. The ma.or focus is the a.plica.ion of the designed MR-compa.ible robotic system to MRI-guided bra.n biopsy. Na.iga.ion a.d opera.ing modules were designed to underta.e the a.ignment a.d a.va.cement of the surgica. needle respectively. The mecha.ica. design a.d control pa.a.igm a.e reported.