摘要：Although some experiments have shown that point defects in a cathode host material may enhance its performance for lithium-sulfur battery(LSB),the enhancement mechanism needs to be well investigated for the design of desired sulfur ***,the first principle density functional theory(DFT)is adopted to investigate a high-performance sulfur host material based on oxygen-defective TiO2(D-TiO2).The adsorption energy comparisons and Gibbs free energy analyses verify that D-TiO2 has relatively better performances than defect-free TiO2 in terms of anchoring effect and catalytic conversion of ***,D-TiO2 is capable of absorbing the most soluble and diffusive long-chain *** newly designed D-TiO2 composited with three-dimensional graphene aerogel(D-TiO2@Gr)has been shown to be an excellent sulfur host,maintaining a specific discharge capacity of 1,049.3 mAhg^−1 after 100 cycles at 1C with a sulfur loading of 3.2 mgcm^−*** with the sulfur mass loading increasing to 13.7 mgcm^−2,an impressive stable cycling is obtained with an initial areal capacity of 14.6 mAhcm^−2,confirming the effective enhancement of electrochemical performance by the oxygen *** DFT calculations shed lights on the enhancement mechanism of the oxygen defects and provide some guidance for designing advanced sulfur host materials.

摘要：In searching for novel fungicidal leads,a series of pyrazole-containing strobilurins were rationally designed,synthesized and *** indicated that compound 1-7 displayed excellent fungicidal activity against a broad spectrum of plant pathogens such as Gibberella zeae,Rhizoctonia cereolis,Sclerotinia sclerotiorum,Phytophthora infestans,Physolosporo piricola and Pellicularia sosakii with EC_(50) of 0.16,0.02,0.72,0.07,0.77 and 0.65μg/mL,respectively,which were 3-10 times more potent than the positive control azoxystrobin against the corresponding ***,like azoxystrobin and kresoxim methyl,1-7,displayed excellent protec-tive activity against *** docking validated that 1-7 and azoxystrobin would share a similar binding mode with cytochrome bc_(1) *** study demonstrates that 1-7 is a promising fungicidal candidate for further development.

摘要：Effects of Reynolds(Re)number and Schmidt(Sc)number on the flow structures and variable density mixing are numerically investigated through the canonical shock cylindrical bubble *** determining the viscosity and diffusivity within a wide range,the controlling parameters,total vortex circulation,and compression rate,are conservative under a broad range of Re and Sc numbers(Re≈10^(3)-10^(5)and Sc≈0.1-5)in the same shock Mach(Ma)number condition(Ma=2.4).As for the Re number effect,the circulation of secondary baroclinic vorticity(SBV),induced by the main vortex centripetal acceleration,is observed to be higher in high Re number and vice *** on the vorticity transport equation decomposition,a growth-inhibition vorticity dynamics balance mechanism is revealed:the vorticity viscous term grows synchronously with baroclinic production to inhibit SBV production in low Re *** contrast,the viscous term terminates the baroclinic term with a time lag in high Re number,leading to the SBV *** the SBV reflects the local stretching enhancement based on the advection-diffusion equation,mixing is influenced by the Sc number in a different behavior if different Re numbers are *** time-averaged variable density mixing rate emerges a scaling law with Sc number asχ^(∗)=β·Sc^(−α),where the coefficientβ∼Re−0.2 and the scaling exponentα∼Re−*** understanding of Re number and Sc number effect on variable density mixing provides an opportunity for mixing enhancement from the perspective of designing the viscosity and diffusivity of the fluid mixture.

摘要：Antibacterial nanoagents with broad-spectrum antibacterial activities have emerged as an evolution of ***,their bacteria-capturing capability and bacteria-killing efficiency remain insufficient for commercial *** by the hunting behavior of spiders,here,a novel spiderweb-like nanoagent based on silver-adenine nanowires is designed to achieve high-efficiency capture and killing of *** virtue of the initiative bacteriacapturing functionality,this spiderweb-like nanoagent could effectively attract and trap bacteria through electrostatic interaction and its reticular morphology ***,its synergetic antibacterial mechanism combining physical membranolysis with reactive oxygen species(ROS)release allows such nanoagent to harvest a promoted bactericidal ***,the woundplast employing the spiderweblike nanoagent exhibits a superior antibacterial efficacy against drug-resistant Gram-negative Escherichia coli and Gram-positive methicillin-resistant Staphylococcus aureus compared with commercially available *** work may pave a new way for rational design of new generation bactericidal agents facing the future super-bacteria booming.

摘要：针对有向拓扑下一般非线性多智能体系统中参数不确定和系统通信能力受限等问题,本文提出了一种结合模型参考自适应和事件触发机制的一致性控制协议.该协议首先为每个参数不确定的智能体设计一个参考智能体,其中自适应律的设计保证了不确定参数的有效估计,然后基于事件触发机制向邻居智能体发送参考智能体状态,最后基于接收的邻居参考智能体状态及自身实际状态设计控制器.采用对参考智能体设计事件触发策略的方式,可以有效避免智能体间的连续通信,减少系统通信资源.利用矩阵论、代数图论以及Lyapunov稳定性理论,证明在该控制协议下,含参数不确定一般非线性多智能体系统能实现一致性,且不存在Zeno行为.仿真实例进一步验证了理论结果的有效性.

摘要：X射线计算机断层扫描技术(X-ray computed tomography,CT)是目前临床医学诊断中最为重要的工具之一.临床使用的CT造影剂主要是一些有机碘类小分子,但是这类小分子造影能力有限、体内循环时间短,极大地限制了CT成像技术在疾病诊断中的应用.相比之下,CT成像纳米探针不仅极大地提升了造影能力,同时具有更好的生物相容性和更长的体内循环时间.更重要的是,其表面易修饰特性有助于多功能成像探针的构建.本文针对近年来CT成像纳米探针的设计及应用进行了简要介绍,并展望了其未来的发展方向.

摘要：Theranostic nanoprobes can potentially integrate imaging and therapeutic capabilities into a single platform,offering a new personalized cancer diagnostic ***,there is a growing concern that their clinical application is not safe,particularly due to metal-containing elements,such as the gadolinium used in magnetic resonance imaging(MRI).We demonstrate for the first time that the photothermal melting of the DNA duplex helix was a reliable and versatile strategy that enables the on-demand degradation of the gadolinium-containing MRI reporter gene from polydopamine(PDA)-based theranostic *** combination of chemotherapy(doxorubicin)and photothermal therapy,which leads to the enhanced anti-tumor *** vivo MRI tracking reveals that renal filtration was able to rapidly clear the free gadolinium-containing MRI reporter from the mice *** results in a decrease in the long-term toxic effect of theranostic MRI *** findings may pave the way to address toxicity issues of the theranostic nanoprobes.

摘要：在腈纶生产过程中,聚合反应是关键环节之一。鉴于聚合反应的复杂性和危险性,通过对聚合反应原理及其危险性、安全控制系统设计注意事项的分析,找到安全设计的保障措施。采用对比分析研究方法,分别对安全控制系统设计中安全泄放系统、DCS阀门仪表及DCS连锁方式、SIS阀门仪表及SIS连锁方式、可燃/有毒气体连锁的设置进行研究对比,从而得到符合国家重点监管工艺设计规定的安全控制系统,通过合理设置温度、压力、液位控制以及紧急停车系统和安全联锁系统,可以有效地保障生产安全。

摘要：根据柑橘溃疡病菌(Xanthomonas citri ***,Xcc)基因组的保守序列设计特异引物,通过对引物浓度、反应温度和反应时间条件优化,建立了柑橘溃疡病菌重组酶聚合酶扩增(Recombinase polymerase amplification,RPA)检测方法。该方法无需PCR仪等复杂设备,在39℃恒温反应30 min即可完成检测过程,快速简便。该检测方法与其他柑橘病原无交叉反应,特异性强;检测灵敏度是普通PCR的100倍,与实时荧光定量PCR基本一致。对71个柑橘样品进行检测,RPA检测出溃疡病阳性样品22个,与PCR、实时荧光定量PCR检测结果一致。

摘要：通过分子设计制备一种含双叔丁基结构的刚性芳香二胺单体——4,4′-二氨基苯基-3″,5″-二叔丁基甲苯,将该二胺单体分别与3种不同的商品化芳香二酐(3,3′,4,4′-联苯四酸二酐(BPDA)、3,3′,4,4′-二苯醚酐(ODPA)、3,3′,4,4′-二苯酮四酸二酐(BTDA))采用一步高温缩聚制备了3种新型聚酰亚胺NPI(3a~3c)。该类聚酰亚胺具有优异的溶解成膜性能,在室温可溶解于N-甲基-2-吡咯烷酮、N,N-二甲基乙酰胺、间甲酚等高沸点溶剂中,在加热时还能溶解于CHCl_(3),CH_(2)Cl_(2),THF等低沸点溶剂,并可通过其聚合物溶液浇铸得到柔韧的薄膜;所制聚酰亚胺薄膜具有优良的热性能,玻璃化转变温度(T_(g))范围为262~303℃,在N_(2)中质量损失10%的温度超过523℃;具有优异的光学性能,所制薄膜还具有较浅的颜色和良好的光学透过性,在450 nm波长光下的透光率为69%~76%,截止波长为341~353 nm。