摘要：基于射流穿透长度与夹带液滴分数等水力模型,建立了混合气体射流条件下气溶胶惯性碰撞去除模型,通过对注入区空间离散构建了高韦伯数射流流型含气芯夹带特征的气溶胶水洗去除分析方法。采用气溶胶水洗机理实验装置开展的两组蒸汽份额为64%,淹没深度为0.7 m,质量通量分别为217 kg/(m^(2)·s)和120 kg/(m^(2)·s)实验,以及引用淹没深度为0.5 m、质量通量为95 kg/(m^(2)·s)的纯不凝性气体载带气溶胶的RCA2实验结果,对分析方法进行了验证。结果表明:考虑射流水力学特征的气溶胶水洗去除模型的预测结果与实验值符合较好,通过参数分析发现随着射流韦伯数的增加,射流穿透长度和夹带液滴分数均增加,增强了气溶胶与液滴的惯性碰撞作用。

摘要：A series of urea-based compounds containing purine moieties were designed and synthesized as novel non-ATP competitive CHK1 inhibitors. The biological evaluation showed that several target compounds exhibited more potent inhibitory effects against CHK1 than the lead compound. In addition, one particular compound displayed synergistic effects with gemcitabine against HT29 cells.

摘要：Three series of novel anti-immunodeficiency virus 1 （HIV-1） dual （RT/1N） inhibitors were rationally designed by introducing a functioning diketo acid （DKA） into pyridin-2-one scaffold. To efficiently analyze inhibitory activity, these compounds were screened against HIV-1 RT and IN respectively via surface plasmon resonance （SPR）, and active compounds were subsequently evaluated by enzyme assay. It was noteworthy that compound A2 exhibited moderate activity against both HIV-1 RT and IN. This result provided information for further development of pyridinone analogues as potent dual HIV-1 inhibitors.

摘要：In the present study,novel ester derivatives of CAPE were designed and synthesized as neuroprotective *** anti-inflammatory and antioxidant activities of these compounds were evaluated at the cellular level,while the blood-brain barrier(BBB)permeability was predicted by parallel artificial membrane permeability assay(PAMPA).The results revealed that phenolic hydroxyl groups and double bonds in the structure of CAPE had important effects on neuroprotective ***,a preliminary structure-activity relationship was summarized in this *** addition,we observed a significant improvement on BBB *** results provided important references for the structural modification and optimization of CAPE in the future.

摘要：Intensive studies have been carried out on generations of waverider geometry and hypersonic inlet geometry. However, integration efforts of waverider and related air-intake system are restricted majorly around the X43A-like or conical flow field induced configuration, which adopts mainly the two-dimensional air-breathing technology and limits the judicious visions of developing new aerodynamic profiles for hypersonic designers. A novel design approach for integrating the inward turning inlet with the traditional parameterized waverider is proposed. The proposed method is an alternative means to produce a compatible configuration by linking the off-the-shelf results on both traditional waverider techniques and inward turning inlet techniques. A series of geometry generations and optimization solutions is proposed to enhance the lift-to-drag ratio. A quantitative but efficient aerodynamic performance evaluation approach （the hypersonic flow panel method） with lower computational cost is employed to play the role of objective function for opti- mization purpose. The produced geometry compatibility with a computational fluid dynamics （CFD） solver is also verified for detailed flow field investigation. Optimization results and other numerical validations are obtained for the feasibility demonstration of the proposed method.

摘要：By integrating photoinduced electron transfer（PET） into the design of functional bioluminogenic probes,Urano and his coworkers recently developed a new rational design strategy, BioLeT. It is expected that this BioLeT strategy will enable us to design and develop new bioluminescence probes for detecting various biomolecules with no catalytic or reactive activity.

摘要：一、广告文化必须体现民族文化的基本特性广告的目的在于创造品牌形象、营销产品或传播某种观念.

摘要：锂离子电池(LIBs)以其高能量密度、低自放电率和长寿命等优势,广泛应用于电子设备、电动汽车及新兴飞行汽车(eVTOL)领域。飞行汽车的电池需要克服高能量密度、高功率密度、快速充电、长循环寿命和高安全性等问题。开发高比能锂离子电池系统需要优化每个电池组件,从电极和电解质到黏结剂系统。黏结剂在LIBs中起到了关键的作用,可以提高电极的机械强度和黏附性,改善电极的导电性和离子传输能力。然而传统的黏结剂,在满足高比能量LIBs需求方面存在诸多局限性,需要开发能够与新型电极材料和电化学材料相兼容的新型功能黏结剂。在本文的综述中,从高能量密度、高功率密度、快速充电、长循环寿命和高安全性的LIBs出发,综述各种前沿的新型黏结剂,提出了下一代高密度锂离子电池黏结剂的设计策略,并概述未来黏结剂的研究方向和面临的挑战。

摘要：This paper describes a novel finite element thermal analysis model for an AIGalnP-LED micro-array device. We also conduct a transient analysis for the internal temperature field distribution of a 5x5 array device when a 3x3 unit is driven by pulse current. In addition, for broader applications, a simplified thermal analysis model is introduced and its accuracy is verified. The internal temperature field distribution of 100xl00 units is calculated using the simplified model. The temperature at the device center reaches 360.6 ℃ after 1.5 s. In order to solve the heat dissipation problem of the device, an optimized heat dissipation structure is designed, and the effects of the number and size of the heat dissipation fins on the thermal characteristics of the device are analyzed.

摘要：针对汽车轮胎气压工况的特点,设计汽车胎压监测系统(TPMS).采用嵌入式实时操作系统μC/OS-Ⅱ为软件平台,以多任务的形式进行程序设计,并采用性能优越的32位ARM嵌入式处理器作为硬件处理平台.试验结果表明,该系统可有效防止轮胎在非正常气压下长时间行驶而发生事故,提高了汽车的主动安全性.系统的设计为胎压监测提供了一个有效和可靠的解决方案.