摘要：Purpose. Can Cortisol Re.e.sing Hormone.(CRH) le.e.s in follicular fluid pre.ict outcome. following assiste. re.roductive.tre.tme.t (ART) cycle.? Me.hods: Prospe.tive.cohort study of 50 wome. unde.going in vitro fe.tilisation (IVF)/intra-cytoplasmic spe.m inje.tion (ICSI) cycle. ove. a two month study pe.iod. All patie.ts we.e.tre.te. on the.long stimulation protocol;follicular fluid was aspirate. and poole. for e.ch patie.t. The.sample. we.e.proce.se. appropriate.y and assaye. using CRH radioimmunoassay (RIA). Re.ults: This study confirme. that CRH was pre.e.t in follicular fluid. The.ave.age.le.e. de.e.te. was 173 ± 9 pg/mL (me.n ± standard e.ror of me.n [Se.]). The.data sugge.ts a positive.corre.ation of CRH follicular fluid le.e.s gre.te. than 145 pg/mL with succe.sful ART outcome.. Conclusion: The.data indicate. a positive.corre.ation be.we.n ART outcome. and the.pre.e.ce.of follicular fluid CRH le.e.s gre.te. than 145 pg/mL. The.re.ults should be.inte.pre.e. with caution due.to the.small sample.size.and pooling of follicular fluid pe. patie.t. Furthe.more. the.pooling of follicular fluid is not re.re.e.tative.of CRH le.e.s in an individual follicle. and thus, mature.oocyte. This study se.ve. as a re.inde. to what has pre.iously be.n hypothe.ise..