摘要：Photochromic diarylethenes have been widely used in many fields. However, their cyclization process must be induced by UV light. In this article, a simple strategy is developed by extending π-conjugation with electron donating groups. The modified dirylethene derivative can photocyclolize under 405-nm light with a good photochromic efficiency. Meanwhile, its absorption and moderate fluorescence can be switched effectively in both directions by visible lights(405 and 520 nm, respectively) in different solutions and in living cells. We believe that this simple method will become a versatile strategy for developing various dirylethylenes with visible-light photochromism.

摘要：J-aggregates of cyanine have shown great merits in tumor photothermal therapy(PTT)due to their distinct redshift absorption as well as superior photothermal conversion efficiency(PCE).However,due to the complexity of intermolecular interactions,especially the impact of steric hindrance on aggregation,exploring effective strategies to regulate the aggregation modes of organic materials remains ***,steric hindrance-regulated J-aggregation of near-infrared(NIR)cyanine was reported based on Pt-coordinated cyanine self-assembly with unexpected“butterfly effect”.Two Pt-coordinated cyanine dimers CyR-Pt(R=Me and Et)were synthesized and spontaneously self-assembled into aggregates in aqueous ***-Pt aggregates were loose and amorphous *** replacing ethyl with methyl to reduce steric hindrance,a tiny change resulted in the generation of tightly stacked cyanine J-aggregates(thickness less than 3 nm)observed in CyMe-Pt ***,this unexpected“butterfly effect”enabled CyMe-Pt J-aggregates to effectively inhibit reactive oxygen species and greatly improve its ***,CyMe-Pt J-aggregates with NIR-II absorption exhibited outstanding photothermal stability and higher PCE(η=37%)than CyEt-Pt disordered aggregates(η=20%).Evident tumor suppression performance of CyMe-Pt J-aggregates was validated under 980 nm laser irradiation,demonstrating its great potential in tumor PTT.

摘要：本文阐述了该轮椅的结构与工作原理,并运用Solid Works软件对其进行建模、虚拟装配,并进行功率匹配研究。实践证明,该创新型轮椅功能完善、移动灵活、操作简便、安全度与舒适度高,具有一定的应用前景。

摘要：多孔钛合金的设计与力学性能是生物医学领域的研究热点。通过SLM技术设计并制造了2种均质和梯度的Gyroid极小曲面单胞结构,通过对其进行静态压缩试验和拉伸试验并与传统的桁架类单胞结构做对比,建立了5种不同点阵结构的准静态压缩模型。通过Hypermesh与ABAQUS联合仿真的方式,对它们进行了网格划分与分析计算,通过应力应变云图、塑性应变云图以及压缩实验过程的观察,综合分析了空心立方、G7、bcc、均质Gyroid和梯度Gyroid 5种多孔结构失效形式和变形机制,将仿真得出的应力应变曲线与试验结果进行了对比,发现该仿真方法可以较好预测出不同多孔结构的最大抗压强度。压缩和拉伸试验结果表明,Gyroid点阵材料的最大抗拉性能远高于桁架类结构,抗压性能也更优越。其中,G梯度结构的综合力学性能最优。

摘要：背景:有研究显示,在设计多孔种植体时可以通过改变孔隙内部单元结构来改变弹性模量,为更好地平衡种植体强度和弹性模量提供新的方法。目的:通过有限元分析不同微观孔结构牙种植体生物力学性能,阐明不同微观孔结构对周围骨应力和种植体力学性能的影响。方法:通过CT扫描建立下颌骨模型和3种不同孔隙结构(传统结构孔隙、复合结构孔隙、G7结构孔隙)的牙种植体有限元模型,孔隙率为40%,多孔层厚度为1.2 mm,孔径为0.45 mm,模拟极限合力状态对每个模型施加载荷,采用ANSYS有限元软件运算并分析周围骨应力及种植体的应变。结果与结论:(1)当种植体受极限合力,传统结构、复合结构与G7结构牙种植体对周围皮质骨等效应力最大值分别为38.324,56.574,64.694 MPa,对周围松质骨等效应力最大值分别为1.836,10.221,9.439 MPa,种植体等效应力最大值分别为156.38,476.23,457.76 MPa;复合结构种植体的最大周围骨应力在促进骨结合的范围内;(2)当种植体只受侧向力时,传统结构、复合结构与G7结构牙种植体应变最大值分别为2.222 9×10^(-2),1.661 9×10^(-2),3.210 9×10^(-2) mm/mm;当种植体只受轴向力时,传统结构、复合结构与G7结构牙种植体应变最大值分别为2.266 2×10^(-3),1.844 6×10^(-3),2.971 5×10^(-3) mm/mm;说明在受侧向静力载荷和轴向载荷时,复合结构种植体的应变最小,产生的微动小,有助于提高骨结合效果;(3)结果表明,随多孔种植体内部孔隙单元结构的变化,周围骨应力发生明显变化,种植体力学性能也发生明显变化,种植体表面多孔结构的单元胞体结构形状的改变显著影响弹性模量和种植体的力学性能,复合孔隙结构的牙种植体与传统结构和G7结构相比具有更好的生物力学性能。

摘要：文章根据限压阀在压套过程中存在的问题,从工装设计、产品质量、操作方法等方面进行详细的原因分析,采取了相应的改进措施.不仅解决了漏泄惯性质量问题,而且在安全、效率方面取得了较好的效果,值得在压套工序中推广.

摘要：面对航天领域的嵌入式开发板在应用中存在硬件开发制约软件开发、硬件资源紧张、测试不充分等问题,为某型飞控软件依赖的硬件平台引入虚拟化方案。首先,编写AArch64指令测试集验证QEMU动态翻译可信性,并通过调试、追踪、更改、编译QEMU源码成功挂载Flash,在此基础上,构建虚拟网络打通数据传输链路,新建虚拟外设并通过重构设备驱动、重定向内核驱动确保外设可用,最终获得自定义虚拟机。其次,新建设备模拟器、调整模型机网络通信模式,联调虚拟机、模拟器、模型机确保数据传输正常,从而顺利搭建虚拟平台。接着,设计支持虚拟平台可视化搭建、源码远程调试、目标码覆盖率统计等功能的集成开发环境,提升虚拟平台便捷性和可靠性。最后,观测到某型飞控软件在真实平台和虚拟平台中仿真结果一致,验证了虚拟平台真实可用。