摘要：The response surface methodology(RSM) combined with bioassays was employed to optimize the extraction process of crude fucose-containing sulphated polysaccharides(c FCSP) from Sargassum fusiforme. The central composite design(CCD) was used with four variables, five levels, and four responses. The four variables were p H value of hydrochloric acid solution, extraction temperature(℃), ratio of liquid to raw material(m L g^(-1)), and extraction time(h), respectively. Chemical and bioassay indices were used in combination as the response parameters, which included the yield of c FCSP, fucose content, proliferation rate of spleen cells, and lipopolysaccharide-induced proliferation of splenocytes. The experimental data were fitted to a second-order polynomial equation using multiple regression analysis, and examined using the appropriate statistical methods. The best extraction conditions were as follows: the p H value of hydrochloric acid solution was 3.50; the extraction temperature was 100℃; the ratio of liquid to raw material was 15.00 m L g^(-1) and the extraction time was 2.50 h. The experimental yield was close to the predicted from the model. The extract could promote spleen lymphocyte proliferation, especially the lipopolysaccharide-induced lymphocyte proliferation in vitro, which suggested that its immunomodulatory effect on B lymphocytes. Therefore, c FCSP extracted from S. fusiforme could be utilized as an immunostimulant in functional foods and pharmaceutical industry in future.

摘要：柔性翻边成形是一种局部连续加载的翻边新工艺,其工艺规律和规划方法尚不完善.结合航空钣金结构件的特点,设计特征翻边件,基于Abaqus平台进行柔性翻边成形工艺的仿真研究,总结翻边道次数、各道次角度分配、滚轮直径和滚压速度等关键工艺参数对成形质量的影响规律.综合考虑成形效率,优化工艺参数设计,并进行试验验证.结果表明:对关键工艺参数进行优化设计,能够低成本地显著提高柔性翻边的成形质量,并在一定程度上提高成形效率.

摘要：开发了一种可转工作台的柔性翻边新工艺,有效解决目前多品种小批量钣金件手工翻边成形存在的生产噪音大、工作强度高的难题。新工艺利用机器人带动滚轮,规划多道次轨迹路径,实现了零件的翻边成形。自行开发可转工作台,实现恒定滚压力翻边,避免了使用固定工作台翻边时,因机器人位姿不同引起的零件中间贴模间隙小,两端贴模间隙大的问题。通过实验对比了固定工作台与可转工作台的效果。并针对柔性翻边的质量问题提出改进方法。

摘要：介绍了三峡地下电站进水塔门式启闭机电气变频控制系统的安装调试技术要点,并对其调试过程中的常见故障进行了分析处理,为该系统在水电站起重设备中的运行应用,提供参考经验。

摘要：因量子级联激光器的工作波长可覆盖红外到太赫兹波段,在大气污染检测、工业污染监控、医学诊断、毒品及生化危险品灵敏检测、自由空间通信等领域具有广泛的应用前景。从1994年问世到现在,量子级联激光器已经从最初的实验室原理器件发展到可实用化的红外波段最具发展前景的半导体激光器。本文从量子级联激光器设计思路的演进、工作波长范围的扩展、提高输出功率、实现单模的宽调谐、提高光束质量等方面依次介绍相应的研究进展,最后给出简要总结与展望。