摘要：Oxidized Bacterial Cellulose （OBC）-hydroxyapatite （HAp）-gelatin （Gel） nanocomposites were prepared by a biomimetic process. HAp nanocrystals were precipitated in a mixed solution ofNa2HPO4 （pH 9.2） and Gel solution at 37 ℃, and OBC was used to generate a three-dimensional （3D） network stent. The tensile strength of OBC-HAp-G was higher than 0.3 MPa, and the complete degradation time was approximately 90 d in Simulated Body Fluid （SBF）. Fourier transform infrared spectroscopy demonstrated that a coordinate bond had formed possibly between HAp and the cellulose hydroxyl. X-ray diffraction showed that both the oxidation of bacterial cellulose and an increase in Gel content induced the formation of tiny HAp crystallites during composite fabrication. Specific surface area and porosity measurements indicated that a low Gel concentration contributed to retention of porous structure. The Ca and P contents on the surface of materials increased initially and then decreased with an increase in Gel content, as measured by energy dispersive spectroscopy. From the thermogravimetric data, the increase in decomposition temperature suggested the formation of chemical bonds among OBC, HAp, and Gel. The above results suggest that the OBC-HAp-G0.3 composite is a potential bone scaffold material.

摘要：Integrated computational materials engineering (ICME) is an emerging discipline that can speed up product development by unifying material, design, fabrication, and computational power in a virtual environment. Developing and adapting ICME in industries is a grand challenge technically and culturally. To help develop a strategy for development of this new technology area, an ICME approach was proposed and implemented in optimizing thin welded structure design. The key component in this approach is a database which includes material properties, static strength, impact strength, and failure parameters for a weld. The heat source models, microstructure model, and thermo-mechanical model involved in ICME for welding simulation were discussed. The shell elements representing method for a fusion weld were introduced in details for a butt joint, lap joint, and a Tee joint. Using one or multiple solid elements representing a spot weld in a shell model was also discussed. Database building methods for resistance spot welding and fusion welding have been developed.

摘要：The exploitation of competent electrocatalysts is a key issue of the broad application of many promising electrochemical processes,including the hydrogen evolution reaction(HER),the oxygen evolution reaction(OER),the oxygen reduction reaction(ORR),the CO_(2) reduction reaction(CO_(2)RR)and the nitrogen reduction reaction(NRR).The traditional searches for good electrocatalysts rely on the trial-and-error approaches,which are typically tedious and *** the past decades,some fundamental principles,activity descriptors and catalytic mechanisms have been established to accelerate the discovery of advanced ***,it is time to summarize these theory-related research advances that unravel the structure-performance relationships and enables predictive ability in electrocatalysis *** this review,we summarize some basic aspects of catalytic theories that are commonly used in the design of electrocatalysts(e.g.,Sabatier principle,d-band theory,adsorption-energy scaling relation,activity descriptors)and their ***,we briefly introduced the fundamental mechanisms and central challenges of HER,OER,ORR,CO_(2)RR and NRR electrocatalysts,and highlight the theory-based efforts used to address the challenges facing these electrocatalysis ***,we propose the key challenges and opportunities of theory-driven electrocatalysis on their future.

摘要：The development of efficient oxygen evolution electrocatalysts with reduced noble metal uses is a critical challenge for the deployment of various advanced energy conversion ***,a series of lanthanide-contained 6H-perovskites with a formula of Ba3LnIr2〇9(Ln=lanthanides)are investigated as oxygen evolution electrocatalysts,whose active subunits(i.e.,face-sharing Ir〇6 dimers)can be regulated by the lanthanides in terms of catalytic *** using density functional theory(DFT)calculations,we establish the theoretical trend in activity for Ba3LnIr2〇96H-perovskites,the activity of which is correlated with the difference of adsorption free energy(△G〇-△Goh)between O*and OH*reaction *** further establish a volcano curve between△Go—△Goh and the calculated 0 p-band center Among the Ba3LnIr2〇96H-perovskites,Ba3Lalr2〇9 locates at the peak of volcano curve,and correspondingly is the most active electrocatalyst due to the optimal 0 p-band property.

摘要：Entity recognition and disambiguation （ERD） is a crucial technique for knowledge base population and information extraction. In recent years, numerous papers have been published on this subject, and various ERD systems have been developed. However, there are still some confusions over the ERD field for a fair and complete comparison of these systems. Therefore, it is of emerging interest to develop a unified evaluation framework. In this paper, we present an easy-to-use evaluation framework （EUEF）, which aims at facilitating the evaluation process and giving a fair comparison of ERD systems. EUEF is well designed and released to the public as an open source, and thus could be easily extended with novel ERD systems, datasets, and evaluation metrics. It is easy to discover the advantages and disadvantages of a specific ERD system and its components based on EUEF. We perform a comparison of several popular and publicly available ERD systems by using EUEF, and draw some interesting conclusions after a detailed analysis.

摘要：目的以广告中图形创意设计的表现力为切入点,分析如何提高图形设计的能力。方法对图形以及图形创意的概念进行系统的诠释,以内涵动态为依据,将图形语言进行分类比较和论述,最终得到广告图形创意设计的表现方法。结论通过分析案例,从不同角度和深度归纳总结出一系列创意特征和表现方法,从而更专业地解读和完善广告图形创意设计。

摘要：以马鞍山郑蒲港新区排涝系统为代表性案例,探讨基于调蓄演算法和SWMM模型联合的城市排水系统设计应用研究。郑蒲港新区于2012年设立,定位为现代临港物流区、现代临港工业区及产城一体主城区,具有重要的战略发展功能。首先,收集新区地理、气候和排水系统相关数据,运用基于水量平衡的调蓄演算方法对排涝系统及规模进行分析。然后,将优化方案应用于SWMM模型,对雨水径流等过程进行动态模拟和分析。研究表明,为达到20年一遇暴雨不积水的设计排涝标准,研究区域需外排总设计流量为111.9 m^(3)/s,扣除现有3座泵站合计流量后,尚需增加30.5 m^(3)/s外排流量。研究成果为郑蒲港新区姥下河北片区的排涝减灾和排涝系统整治提供科学参考依据,有助于新区发展建设需要。同时,此研究方法可作为基于调蓄演算法和SWMM模型联合的城市排水系统设计应用研究的参考,推动城市排水系统设计领域的发展。

摘要：Background and aim:Progressive muscle relaxation(PMR)is one of the most common complementary and alternative *** systematic review unfolded that PMR has a positive impact on chemotherapy-induced nausea and vomiting among adult cancer ***,the pooled findings were not reliable and valid because included trials have poor *** must be noted is that additional studies with good quality have been published ***,we design this updated systematic review to comprehensively establish the efficacy of PMR for the of chemotherapy-induced nausea and vomiting among cancer ***:We will search PubMed,Cochrane Controlled Register of Trial(CENTRAL),Cumulative Index to Nursing and Allied Health Literature(CINAHL),China Biomedical Literature database(CBM),China National Knowledge Infrastructure(CNKI),and Wanfang data to capture all potential *** extraction sheet will be used to extract all essential information,the Cochrane risk of bias assessment tool will be utilized to appraise the risk of bias of eligible ***,a quantitative analysis will be performed if sufficient data were *** contrast,a qualitative analysis will be used to summarize the results of all included *** and dissemination:Ethics approval and patient written informed consent will not be required because all of the analyses in the present study will be performed based on data from published *** will submit our systematic review and network meta-analysis to a peer reviewed scientific journal for publication.

摘要：The vicious cycle between tumor cell proliferation and bone resorption remarkably elevates the progression and metastasis of bone ***,we fabricated polyethylene glycol-conjugated alendronate-functionalized and chloroquine(CQ)-loaded polydopamine nanoparticles(PPA/CQ)for efficient treatment of bone tumors via breaking the vicious *** nanoparticles were efficiently accumulated to the bone tissues,especially the osteolytic lesions around *** released from PPA/CQ inhibited osteoclastogenesis via preventing the degradation of tumor necrosis factor(TNF)receptor-associated receptor 3 to attenuate the osteolysis in bone *** the other hand,CQ blocked the autophagy in cancer cells,resulting in improved photothermal killing of cancer ***,the in vivo experiment revealed that PPA/CQ-associated treatment efficiently inhibited both tumor growth and *** work suggests that autophagy inhibition-associated photothermal therapy could be a promising strategy for treating malignant bone tumors.

摘要：民俗艺术图形符号是人类通过视觉形象传达民俗文化的一种符号形式,是劳动者集体民俗观念和审美意识的产物。现代广告设计中的民俗图形符号大多来自民俗活动,在一定程度上保留传统本土民俗艺术的特点,同时也融入了现代经济文化的元素。对民俗艺术图形符号的运用不仅丰富了现代广告设计作品的内涵,而且使传统文化得以广泛传播。民俗艺术中的图形符号已成为现代广告设计中不可或缺的重要组成部分。