摘要：文章通过论述“创意是VI整体策划的灵魂”、“定位是VI整体策划的眼睛”、“表现是VI整体策划的形体”这三点来论证了“创意建立于定位,通过表现提升创意价值”。

摘要：随着数字时代的发展,视觉传达设计领域迅速拓宽,设计的表现手段、范围和效果得到了极大的扩展。未来的视觉传达设计是综合性的、内涵丰富的和变化迅速的全新设计形态,是涵盖了人类全部感官的全面设计。数字时代不可避免地冲击和影响着视觉传达设计的发展,从而引发了设计新观念的产生,即技术支配化、设计创新化、设计大众化、方法多样化和媒介整合化。

摘要：Novel chiral tetralin compounds were designed and synthesized, and their antifungal activities in vitro were tested. The results showed that all of target compounds had potent antifungal activities, and were stronger than that of control compounds tetrahydroisoquinolines. The binding model of lead molecules in the active site of CYP51 of Candida albicans showed that lead compound specifically interacted with the amino acids residues in the active site, without binding with the heme of CYP51, which was different from azole antifungal drugs. The present study might afford a novel lead molecule to develop non-azole CYP51 inhihitars of fungi.

摘要：目的研究针对湖湘文创产品设计结果评价的指标体系构建方法与流程。方法将文创产品的设计与评价置于产品情境系统中,建立湖湘文创产品情境系统模型,通过对模型纵向与横向上的分析和整合,获得设计评价体系构建脉络。运用脉络分析、文献研讨、专家问卷调查、因子分析等定性与定量研究结合的方法,构建湖湘文创产品设计评价指标体系。结论经验证与实际应用,所构建的评价指标体系对湖湘文创产品设计结果的快速基础性评价具有切实效用,提供了湖湘文创产品的优劣判断参照及文创产品的设计评价研究新思路。

摘要：设计师的自身素质体现着其设计品位。现代设计师只有加强自身整体素质,包括加强自身的创新意识,积累渊博的知识,提高设计素质,掌握运用电脑辅助设计手段的技术素质,拥有对新兴学科敏锐的感觉能力和接受能力的认知素质,才能从本质上拓展设计能力,提高设计品位。

摘要：21世纪以来,原创图画书的兴起成为“一种自觉的、成规模的创作和出版行为,成为一种受到读者普遍关注的文学现象”①。与此相对应,儿童文学研究界也越来越关注原创图画书,针对其的研究成果数量逐年增长。毫无疑问,对原创图画书的探讨已成为儿童文学特别是中国儿童文学研究新的学术增长点。图画书是融合了语言文字和视觉艺术两套表意系统的儿童文学文类,其本身的文类规约决定其兼具儿童性、文学性、视觉性、创意性和开放性。因此,对图画书的研究也必然采取多维度、多层次和跨学科的方法。

摘要：Conventional blood sampling for glucose detection is prone to cause pain and fails to continuously record glucose fluctuations in *** glucose monitoring based on implantable electrodes could induce pain and potential tissue inflammation,and the presence of reactive oxygen species(ROS)due to inflammationmay affect glucose *** technology is less invasive,yet microneedle adhesion with skin tissue is *** this work,we developed a microarrow sensor array(MASA),which provided enhanced skin surface adhesion and enabled simultaneous detection of glucose and H_(2)O_(2)(representative of ROS)in interstitial fluid in *** microarrows fabricated via laser micromachining were modified with functional coating and integrated into a patch of a three-dimensional(3D)microneedle *** to the arrow tip mechanically interlocking with the tissue,the microarrow array could better adhere to the skin surface after penetration into *** MASA was demonstrated to provide continuous in vivo monitoring of glucose and H_(2)O_(2) concentrations,with the detection of H_(2)O_(2) providing a valuable reference for assessing the inflammation ***,the MASA was integrated into a monitoring system using custom *** work provides a promising tool for the stable and reliable monitoring of blood glucose in diabetic patients.

摘要：数字时代背景下的视觉传达设计已进入多元化时期,并呈现出多种风格并存、多姿多彩的局面。本文从设计多元化的必然性,多元化下的中国式设计,以及多元化与差异化的融合三个方面进行论述,指出当代数字技术推动了视觉传达设计的迅速发展,并呈现出欣欣向荣的多元化发展态势。

摘要：Modern medicine is increasingly interested in advanced sensors to detect and analyze biochemical *** sensors based on potentiometric methods are a promising platform for monitoring physiological ions in biological *** semi-implantable devices are mainly based on single-parameter *** semi-implantable electrodes for multiparameter sensing have more restrictions on the electrode size due to biocompatibility considerations,but reducing the electrode surface area could potentially limit electrode *** study developed a semi-implantable device system comprising a multiplexed microfilament electrode cluster(MMEC)and a printed circuit board for real-time monitoring of intra-tissue K^(+),Ca^(2+),and Na^(+)*** electrode surface area was less important for the potentiometric sensing mechanism,suggesting the feasibility of using a tiny fiber-like electrode for potentiometric *** MMEC device exhibited a broad linear response(K^(+):2–32 mmol/L;Ca^(2+):0.5–4 mmol/L;Na^(+):10–160 mmol/L),high sensitivity(about 20–45 mV/decade),temporal stability(>2weeks),and good selectivity(>80%)for the above *** vitro detection and in vivo subcutaneous and brain experiment results showed that the MMEC system exhibits good multi-ion monitoring performance in several complex *** work provides a platform for the continuous real-time monitoring of ion fluctuations in different situations and has implications for developing smart sensors to monitor human health.

摘要：The experimental and numerical investigations on electromagnetic control of cylinder wake have been performed in this paper. Experiments were conducted in a rotating annular tank filled with a low-conducting electrolyte. A cylinder with an electromagnetic actuator mounted on the surface was placed into the electrolyte. Force measurements have been carried out by strain gages attached to a fixed beam to which the hydrofoil is suspended and flow fields are visualized by dye markers. Based on the Navier-Stokes equations considering the electromagnetic body force, i.e. Lorentz force, in the ex- ponential-polar coordinates, the numerical investigations were carried out by means of an Alterna- tive-Direction Implicit algorithm and a Fast Fourier Transform algorithm. Experimental results have shown the same tendency with the numerical results. For the constant Lorentz forces, called open-loop control, the vortex shedding was fully suppressed. Meanwhile, the weak street disappeared and the drag force was reduced. Based on the Navier-Stokes equations, an adjoint-based ensemble optimiza- tion of control algorithms was developed and adjoint equations in the exponential-polar coordinates were derived. The equations were solved by numerical algorithm as mentioned above. The evolutions of the flow field in the control process were discussed according to the calculated variable optimal interaction parameters.