摘要：Objective It has been reported that B-cell lymphoma 2 （Bcl-2） enhances neurogenesis as well as supporting axonal growth after injury. In the present study, we investigated whether Bcl-2 overexpression plays a role in the formation of newborn striatonigral projection neurons in the adult rat brain after transient middle cerebral artery occlusion （MCAO）. Methods We infused human Bcl-2-expressing plasmid （pBcl-2） into the lateral ventricle immediately after 30 min of MCAO, injected 5＇-bromodeoxyuridine （BrdU） intraperitoneally to label proliferative cells, and microinjected fluorogold （FG） into the substantia nigra at 11 weeks of reperfusion followed by multiple immunostaining of striatonigral projection neurons at 12 weeks. Results We found that pBcl-2 treatment significantly increased the number of newborn neurons （BrdU＋-NeuN＋） in the striatum ipsilateral to the MCAO. We further detected newborn striatonigral projection neurons （BrdU＋-FG＋-NeuN＋） in the ipsilateral striatum at 12 weeks. More interestingly, the number of newborn striatonigral projection neurons （BrdU＋-FG＋） was significantly increased by pBcl-2 treatment compared to that by pEGFP, a control plasmid. Conclusion Taken together, we found that Bcl-2 overexpression in the brain enhanced the generation of newborn striatonigral projection neurons. This provides a potential strategy for promoting the reestablishment of neural networks and brain repair after ischemic injury.

摘要：基于Ｐｅｔｒｉ网的节点过多阻碍其广泛应用，在着色Ｐｅｔｒｉ网和递阶着色Ｐｅｔｒｉ网的基础上，分析了递阶着色Ｐｅｔｒｉ网在结构上与面向对象方法的共同之处及其相互联系．指出递阶着色Ｐｅｔｒｉ网可以大大简化Ｐｅｔｒｉ网建模，同时提出了一种把递阶着色Ｐｅｔｒｉ网用于离散事件动态系统的面向对象软件设计的一般方法，并通过对一个柔性制造系统实例的面向对象分析和递阶着色Ｐｅｔｒｉ网的建模，最终指导控制软件的开发．

摘要：研制出一种新型弯曲旋转超声波马达。其定子由一个实心金属柱和粘贴在其上的压电陶瓷片组成。分析了该超声波马达的运动机理,针对新加坡学者所作推导的局限性,根据梁的弹性振动理论,推导出一端固定一端自由的定子在相位差为90°的两个交变电压激励时其端部质点的运动轨迹方程;分析了该马达的定子和转子间接触锥形角的计算方法,为柱形弯曲旋转超声波马达的设计提供了理论指导。

摘要：基于云南观音山煤矿已有的煤层地质条件,针对位于泥质松软岩层中的二井+1100m水平运输大巷破坏严重,原软岩巷道支护设计不能满足使用要求,重新优化了支护参数,并进行模拟分析。采用数值模拟软件FLAC3D,建立了原支护巷道工程地质力学模型,分析巷道变形破坏过程中的应力分布情况,巷道周围形成"两侧"应力集中,常常造成巷道两边剪坏,无锚索支护时,巷道拱顶应力集中程度较高。根据结果重新进行了锚网索支护参数设计,并进行了对比分析。结果表明:增加了锚网索支护后,剪应力分布较为均匀,使巷道深部岩体也承担了浅部围岩的支护荷载,从而减小了巷道的变形量,通过锚索的作用,调动了巷道深部围岩的强度,从到了对巷道浅部围岩的支护效果。

摘要：近年来,武汉市南湖流域排水系统运维状况不佳,基于城市发展需要,排水系统提质改造势在必行。对南湖流域排水系统运行情况进行全面摸查,发现污水稀释、沉积物淤积、危害气体逸散等问题。基于传统重力式和压力式排水系统特点对比,选取民族大道、南湖大道和中南财大区域作为先行示范,新建3个系统性压力式排水系统,对规划和建设方案进行了阐述,有望实现“点对点”传输污水,污水收集和传输效率得到显著提高。压力式排水系统中污水流速较高,能够有效减少危害气体生成,有助于沉积物强制冲刷,对于污水的稳定输送具有重要意义。此外,对南湖流域新建压力式排水系统的经济效益、环境效益和社会效益进行了评价,并分析了工程重难点及运行问题。

摘要：A 3D synchronism deployable antenna was designed, analyzed, and manufactured by our research group. This an-tenna consists of tetrahedral elements from central element. Because there are springs at the ends of some of the rods, spider joints are applied. For analysis purpose, the structure is simplified and modelled by using 2D beam elements that have no bending stiffness. Displacement vectors are defined to include two translational displacements and one torsional displacement. The stiff-ness matrix derived by this method is relatively simple and well defined. The analysis results generated by using software de-veloped by our research group agreed very well with available test data.

摘要：A monolithic optoelectronic integrated circuit chip on a silicon-on-insulator is designed and fabricated based on complementary metal oxide semiconductor compatible *** chip integrates an optical Mach-Zehnder modulator (MZM) and a CMOS driving circuit with the amplification *** results show that the extinction ratio of the MZM is close to 20dB and the small-signal gain of the CMOS driving circuit is about 26.9dB.A 50m V 10 MHz sine wave signal is amplified by the driving circuit,and then drives the MZM successfully.

摘要：基于AMESim仿真平台,结合工程实例(软管恒张力控制系统),以A4VG闭式泵和专用设计的比例恒压控制阀组为基础建立数学模型,对泵的变量控制机构及远程恒压控制调节原理进行仿真分析。在对系统进行仿真和实验的基础上,分析了远程比例溢流阀调定压力和实际工作压力之间的关系和配置不同的阻尼孔对系统调定压力的影响。该系统比泵出口直接加溢流阀调压的方案具有更小的发热量及更好的节能效果,对于该系统在特定工况下的使用起到了一定的启发作用。

摘要：中原历史名窑是指唐宋以来在中原地区出现的著名窑口,瓷种丰富,其艺术所承载的文化内涵超过它自身的实用功能,随着科技的发展,传统制瓷工艺和造物理念被现代工业化生产所抛弃,文章以文化传承视角对中原历史名窑在制瓷过程的烧制技艺进行剖析,梳理陶瓷造物过程中工匠所体现的造物思想。探讨陶瓷工匠在文化传承视角下的生存与发展现状,以点带面,进而对名窑陶瓷烧制技艺的传承与保护提出一些建议和实施路径研究。

摘要：中国(铜陵)国际铜文化创意产业园是国内首个以铜文化为主题,有完整产业链的大型创意产业园。该创意产业园规划以"世界铜都,中国铜谷"为园区的整体形象定位,梳理铜文化历史发展脉络,从中寻找文化元素和设计原形,并结合铜文化创意产业园的规划策略,寻找完整的产业链以及空间、功能和环境的布局方案,以期为同类型的规划项目提供参考。