摘要：Conventional blood sampling for glucose detection is prone to cause pain and fails to continuously record glucose fluctuations in *** glucose monitoring based on implantable electrodes could induce pain and potential tissue inflammation,and the presence of reactive oxygen species(ROS)due to inflammationmay affect glucose *** technology is less invasive,yet microneedle adhesion with skin tissue is *** this work,we developed a microarrow sensor array(MASA),which provided enhanced skin surface adhesion and enabled simultaneous detection of glucose and H_(2)O_(2)(representative of ROS)in interstitial fluid in *** microarrows fabricated via laser micromachining were modified with functional coating and integrated into a patch of a three-dimensional(3D)microneedle *** to the arrow tip mechanically interlocking with the tissue,the microarrow array could better adhere to the skin surface after penetration into *** MASA was demonstrated to provide continuous in vivo monitoring of glucose and H_(2)O_(2) concentrations,with the detection of H_(2)O_(2) providing a valuable reference for assessing the inflammation ***,the MASA was integrated into a monitoring system using custom *** work provides a promising tool for the stable and reliable monitoring of blood glucose in diabetic patients.

摘要：Modern medicine is increasingly interested in advanced sensors to detect and analyze biochemical *** sensors based on potentiometric methods are a promising platform for monitoring physiological ions in biological *** semi-implantable devices are mainly based on single-parameter *** semi-implantable electrodes for multiparameter sensing have more restrictions on the electrode size due to biocompatibility considerations,but reducing the electrode surface area could potentially limit electrode *** study developed a semi-implantable device system comprising a multiplexed microfilament electrode cluster(MMEC)and a printed circuit board for real-time monitoring of intra-tissue K^(+),Ca^(2+),and Na^(+)*** electrode surface area was less important for the potentiometric sensing mechanism,suggesting the feasibility of using a tiny fiber-like electrode for potentiometric *** MMEC device exhibited a broad linear response(K^(+):2–32 mmol/L;Ca^(2+):0.5–4 mmol/L;Na^(+):10–160 mmol/L),high sensitivity(about 20–45 mV/decade),temporal stability(>2weeks),and good selectivity(>80%)for the above *** vitro detection and in vivo subcutaneous and brain experiment results showed that the MMEC system exhibits good multi-ion monitoring performance in several complex *** work provides a platform for the continuous real-time monitoring of ion fluctuations in different situations and has implications for developing smart sensors to monitor human health.

摘要：文化产业与旅游产业密不可分,通过本土文化的植入和品牌文创产品的创意,能够有效提升旅游产品附加值,带动当地经济的转型升级和发展。响堂山石窟位于邯郸市峰峰矿区,主要代表了北齐时期佛教造像、石窟寺及石刻艺术的成就,现为市级以上保护单位,资源十分丰富。本文以响堂山石窟艺术为切入点,通过文创设计将传统文化进行现代创意表达,推动文化传承与创新,促进本地文化与旅游产业的融合发展。

摘要：以教育部文件为指导,以中医药文化价值为核心,重点培养学生的创意行动能力,从实践出发,强调创意成果化,追求提升中医药学子的创新精神、创意思维、审美能力,实现特色鲜明的中医药文化美育。通过对美育课程视觉与生活进行中医药文化创意产品设计的改革创新;实践探索中医药文化创意产品设计的具体改革方式;丰富学生的文创产品成果展示和美育收获的问卷调查反馈,探讨中医药文创产品设计美育教学的有效性和可行性。

摘要：在当今社会,随着科技的不断发展和市场需求的日益多样化,艺术设计类专业应用型人才逐渐受到重视。传统的毕业设计成果不够突出、不切实际,无法满足社会对多元化人才的需要,更得不到社会的认可,学生面临毕业等于失业的现状。文章通过现状分析、改革内容、改革目标等逻辑关系,从设计实践、评价系统、成果转化等角度提出改革,以期为艺术设计类专业毕业设计提供更加合理全面的规范体系,为学生就业搭建最优质的沟通桥梁,同时也促进艺术设计学科建设与专业发展。

摘要：从单体系统迁移到微服务系统是当前业界对遗留系统实施再工程化的主流选项之一,基于单体遗留系统的微服务体系架构重构则是实现该迁移的关键步骤.目前学界多集中在微服务识别方法的研究上;业界虽有许多面向微服务架构的遗留系统重构的实践,但缺乏系统性的方法及高效鲁棒的工具.鉴于此,在微服务识别与模型驱动开发方法前期研究的基础上,研发一种模型驱动的、可用于单体遗留系统微服务化重构的集成设计平台MSA-Lab.它通过分析单体遗留系统运行日志中的方法调用序列,对其中的类和数据表进行类型识别和聚类以构造抽象微服务,同时生成包括微服务图和微服务序列图在内的系统架构设计模型.它包括用于微服务自动识别与设计模型自动生成的核心部件MSA-Generator,以及用于微服务静态结构模型与动态行为模型可视化展现、交互式建模、模型语法约束检验的核心部件MSA-Modeller.在MSA-Lab平台上,通过对4个开源项目实施有效性、鲁棒性、功能转换完备性等实验以及对3个同类型工具实施性能对比实验,结果表明:所提平台拥有很好的有效性、鲁棒性及实现面向日志的功能转换完备性,且性能更加优越.

摘要：目前,病理专家通过肉眼识别显微镜视场下乳腺癌病理切片图像中的乳腺癌细胞具有很强的主观性。因此,设计了一款基于显微图像的乳腺癌细胞识别系统,该系统包括显微图像采集模块和乳腺癌细胞识别算法实现模块。通过USAF 1951分辨率测试板验证设计的乳腺癌细胞识别系统显微图像采集模块,最终的成像分辨率可以达到2.19μm。通过多组乳腺癌病理图像验证所提乳腺癌细胞识别算法,结果表明设计的乳腺癌细胞识别系统识别乳腺癌细胞的平均准确率达到93.4%。

摘要：会展建筑一般具有规模大、功能需求复杂、人流集散量大、火灾荷载高等特点,存在消防车道布置、防火分区划分、安全疏散组织、防排烟系统等消防设计难点,需要采用特殊消防设计手段来解决。本文以某国际会议中心项目为例,通过对其消防设计难点进行深入分析,给出了相应的解决措施,保证了建筑的消防安全,成果可供类似会展建筑参考。

摘要：目的:文章通过解读波普艺术,探究其与当代大众文化之间的联系。方法:从波普艺术的释义、特征、内涵、代表艺术家及主要作品出发,分析波普艺术与当代大众文化的关系。结果:波普艺术是一种集大众消费、流行文化、媒体传播于一体的通俗艺术。从起源和发展来看,其与大众文化有密不可分的关系。波普艺术是大众的、流行的、日常的、通俗的;大众文化同样是流行的、通俗的,具有传播快速的特征,并且与日常生活各方面紧密联系。当代大众文化的流行主要依托新型传播工具,短视频及AI的引入,丰富了传播载体,也引发了人们对波普艺术的再思考。波普艺术兴起于20世纪60年代,以安迪·沃霍尔为代表的艺术家主要使用丝网印刷工艺,运用新的复制技术和综合手法,使大量的图像被批量化生产印刷,这种艺术恰好与二战后美国的消费主义精神相符。结论:在工业化和消费主义的新世界里,人们对文化的深度意义并不关心,但对通俗、消遣、娱乐、类似快餐的图像情有独钟。波普艺术的精神内涵影响着当代大众文化价值取向,是对当今社会流行趋势的一种映射。

摘要：Liquid metals(LM) such as eutectic gallium-indium and gallium-indium-tin are important functional liquid-state metal materials with many unique properties, which have attracted wide attentions especially from soft robot area. Recently the amoeba-like transformations of LM on the graphite surface are discovered, which present a promising future for the design and assemble of self-fueled actuators with dendritically deformable body. It appears that the surface tension of the LM can be significantly reduced when it contacts graphite surface in alkaline solution. Clearly, the specific surface should play a vital role in inducing these intriguing behaviors, which is valuable and inspiring in soft robot design. However, the information regarding varied materials functions underlying these behaviors remains unknown. To explore the generalized effects of surface materials in those intriguing behavior, several materials including glass, graphite, nickel and copper oxides(CuO) were comparatively investigated as substrate *** results were obtained that only LM amoeba transformations were observed on graphite and CuO surfaces. In order to identify the proper surface condition for LM transformation, the intrinsic properties of substrate surfaces, such as the surface charge and roughness, as well as the specific interaction with LM like wetting behavior and mutual locomotion etc., were characterized. The integrated results revealed that LM droplet appears more likely to deform on surfaces with higher positive surface charge density, higher roughness and less bubble generation on them. In addition, another surface material,CuOx, is identified to own similar ability to graphite, which is valuable in achieving amoeba-like transformation. Moreover, this study offers a fundamental understanding of the surface properties in realizing LM amoeba transformations, which would shed light on packing and structure design of liquid metal-based soft device within multi-material s