摘要：广西花山岩画作为世界文化遗产,是中国岩画艺术对外传播的代表,具有极高的艺术价值和文化价值,也是壮族的文化符号。分析花山岩画陶瓷文创产品设计现状和提出设计思路,论述了花山岩画元素在陶瓷文创产品设计中的应用方式,并以设计实践加以论证,从而拓展花山岩画文创产品的创新设计方法,为花山岩画文创产品设计提供理论借鉴和现实意义。

摘要：The ever-decreasing size of transistors requires effectively electrostatic control over ultra-thin semiconductor *** design of the gate configuration can fully persevere the intrinsic property of two-dimensional(2 D)*** we design and demonstrate a 2 D Mo S_(2) transistor with omega-shaped gate,in which the local gate coupling is enhanced by the non-planar *** omega-shaped non-planar transistors exhibit a high current of 0.89 A/lm and transconductance of32.7 l S/*** high performance and desirable current saturation promise the construction of robust logic *** inverters show a voltage gain of 26.6 and an ideal total margin nearly 89%.We also assemble NOT-AND(NAND)gate on an individual Mo S_(2) flake,and the constructed NAND gate demonstrates the universal functionality of the transistors as *** work provides an alternative strategy to fully take the advantages of 2 D materials for high-performance field-effect transistors.

摘要：Early detection of cancer biomarkers applied in real-time disease diagnosis and therapies can increase the survival rate of *** tumor DNA(ct DNA)as a typical cancer biomarker plays a great role in the process of tumor disease monitoring,especially in early ***,most ct DNA detection systems have not been widely used due to their low sensitivity,poor specificity,and high ***,we developed an alternative ct DNA detection system to present the levels of ct DNA by recording the fluorescence signals of the system containing upconversion nanoparticles(UCNPs),Fe_(3)O_(4),and entropy-driven strand displacement *** method has a practical sensitivity with a wide linear range from 100 amol L^(-1)to 1 nmol L^(-1)and a low detection limit of 1.6 amol L^(-1).Furthermore,the system demonstrates a practical application in mouse blood serum samples and meets the requirements for rapid,sensitive,specific,and economical diagnosis of ***,this ct DNA detection system may have great potential for ct DNAdetection and clinical diagnosis.

摘要：The design and synthesis of multifunctional nanocarriers for efficient synergistic cancer therapy have drawn great research interests in recent *** this work,a nanoplatform for chemo-photothermal therapy with targeting ligand was *** porous structured silica nanotubes(SNTs)with controllable lengths decorated with CuS nanoparticles(NPs)on the surface as photothermal agents were prepared and further conjugated with lactobionic acid groups as a cancer cell *** with average lengths of 40,55 and 150 nm were obtained and further functionalized as drug *** smallest bifunctional SNTs with targeting groups show good biocompatibility and highest cellular uptake for HepG2 *** release of doxorubicin hydrochloride(DOX)from the SNTs was dependent on the p H of the buffer solution and 808-nm near infrared(NIR)light *** integration of photothermal therapy(PTT)of CuS NPs and chemotherapy of anticancer drug leads to a better tumor inhibition effect than the individual therapy alone in vitro and in *** results demonstrate potential applications of the nanocomposites as vector for efficient chemo-photothermal therapy.

摘要：Inspired by the limitations of nanoparticles in cancer treatment caused by their low therapeutic effects and biotoxicity,biocompatible and photothermal enhanced copper oxide-decorated carbon nanospheres(CuO@CNSs)with doxorubicin hydrochloride(DOX)loading were *** as photothermal agents were synthesized by a hydrothermal *** was adsorbed on the surface of CNSs,which improved the photothermal conversion efficiency due to the electron transitions between C-2 p and Cu-3 *** addition,CuO would release Cu2+ions in the tumor microenvironment,which could produce hydroxyl radical(·OH)to induce cancer cells apoptosis via Haber-Weiss and Fenton-like *** as a chemotherapeutic agent was located on the surface of CuO@CNSs by electrostatic adsorption and released quickly in the tumor microenvironment to kill cancer *** CuO@CNSs-DOX nanoplatforms realized the combination therapy of photothermal therapy(PTT),chemodynamic therapy(CDT),and chemotherapy(CT),which have strong potential for cancer treatment.

摘要：作为当代日本文化软实力的重要载体,动漫艺术为日本赢得了世界声誉。日本动漫不仅拥有巨大的规模、广泛的受众以及国际化的视野,在作品的主题等方面,也具有深厚的意蕴。而与此同时,不容忽视的是,在光鲜外表的背后,日本动漫艺术中还存在着一些诸如宣扬暴力与色情等内容的阴暗面。

摘要：人工脉冲神经网络通常由多个异质结构的电路单元构成,其中包括具备积分点火功能来产生脉冲信号的神经元模拟器,以及具备记忆功能的突触器件.在本文中,我们设计了一种能进行“同质集成”的相变存储介质Ge-Ga-Sb(GGS)器件,该器件能够同时实现神经元和突触的模拟.在先前的研究中,GGS材料表现出优秀的数据存储功能,例如它具备较高的工作温度(281℃)、较高的十年数据保存温度(230℃)以及较低的电阻漂移.当对该器件改用短脉冲电学操作时,GGS器件首先会发生几个数量级的电阻突变,然后紧接着发生连续的电阻降低.通过透射电子显微镜发现,电阻突变是因为电极之间产生了结晶的导电通道,而电阻缓变是因为导电通道的变粗以及在通道内产生材料分相所致.这种“突变-缓变”的电阻变化特性既可以用来模拟神经元的积分点火功能,也可以模拟突触权重的变化.基于此器件设计的全相变脉冲神经网络,可以实现高达90%的手写数字识别率.

摘要：定向进化是一个循环过程,在构建多样化基因序列和筛选功能基因变体之间交替进行。该技术目前已被广泛应用于DNA序列、基因功能和蛋白质结构的优化和分析。定向进化包括随机基因文库的生成、基因在合适宿主中的表达和突变文库的筛选。构建基因文库的关键是库容量和突变多样性,而筛选变体的关键是高灵敏度和高通量。文中讨论了定向进化技术的最新进展,这些新技术极大地加速和简化了传统的定向进化过程,为定向进化的发展注入了强劲动力。

摘要：In underwater applications of contactless power transmission(CLPT) systems,high pressure and noncoaxial operations will change the parameters of electromagnetic(EM) *** a result,the system will divert from its optimum *** a reluctance modeling method,we investigated the gap effects on the EM coupler in deep-sea *** and measurements were performed to analyze the influence of high pressure and noncoaxial alignments on the *** was shown that it is useful to set a relatively large gap between cores to reduce the influence of *** were carried out to verify the transferring capacity of the designed coupler and system for a fixed *** results showed that an EM coupler with a large gap can serve a stable and efficient power transmission for the CLPT *** designed system can transfer more than 400 W electrical power with a 2-mm gap in the EM coupler,and the efficiency was up to 90% coaxially and 87% non-coaxially in 40 MPa salt ***,a mechanical layout of a 400 W EM coupler for the underwater application in 4000-m deep sea was proposed.

摘要：为了掌握大范围交变梯度高温超导磁铁设计、内凹螺旋形结构的高温超导磁体绕制固定等技术,验证关键技术可行性,中国原子能科学研究院(CIAE)启动了FDF聚焦结构中散焦磁铁的1∶4比例高温超导磁铁研制。为此设计并研制了以小型GM制冷机为冷源的一种冷箱与超导线圈恒温器一体式的氦气循环系统,该系统由2台GM制冷机提供冷量,一台常温循环泵实现氦气循环,整个系统在提供足够的制冷量的前提下,能够确保高温超导线圈的温度均匀分布。该系统可将1∶4比例高温超导线圈最低冷却到25.3 K,完成了超导线圈载流性能的测试和超导线圈磁场特性测试,达到了设计的工作电流和最高磁场。验证了大型无绝缘、干式高温超导线圈在真空状态下采用氦气循环传导冷却方案的可行性,并验证了磁体与低温系统长期稳定运行性能,为新一代等时性高功率固定场交变梯度(FFAG)加速器磁聚焦结构的研制奠定了基础。