摘要：Technological and economic opportunities,alongside the apparent ecological benefits,point to biodesign as a new industrial paradigm for the fabrication of products in the twenty-first *** presented work studies plant roots as a biodesign material in the fabrication of self-supported 3D structures,where the biologically and digitally designed materials provide each other with structural *** a material-driven design approach,we present our systematic tinkering activities with plant roots to better understand and anticipate their responsive *** helped us to identify the key design parameters and advance the unique potential of plant roots to bind discrete porous *** illustrate this binding potential of plant roots with a hybrid 3D object,for which plant roots connect 600 computationally designed,optimized,and fabricated bioplastic beads into a low stool.

摘要：Recently,tissue engineering has developed into a powerful tool for repairing and reconstructing damaged tissues and *** engineering scaffolds play a vital role in tissue engineering,as they not only provide structural support for targeted cells but also serve as templates that guide tissue regeneration and control the tissue *** the past few years,owing to unique physicochemical properties and excellent biocompatibility,various types of two-dimensional(2D)nanomaterials have been developed as candidates for the construction of tissue engineering scaffolds,enabling remarkable achievements in bone repair,wound healing,neural regeneration,and cardiac tissue *** efforts have significantly advanced the development of tissue *** this review,we summarize the latest advancements in the application of 2D nanomaterials in tissue ***,each typical 2D nanomaterial is introduced briefly,followed by a detailed description of its applications in tissue ***,the existing challenges and prospects for the future of the application of 2D nanomaterials in tissue engineering are discussed.

摘要：Although intelligent hydrogels have shown bright potential application in biomedical fields,they were prepared by conventional methods and still face many serious challenges,such as uncontrollable stimulus-response and low response ***,RAFT polymerization provides a versatile strategy for the fabrication of intelligent hydrogels with improved stimulus-response properties,owing to the ability to efficiently construct hydrogel precursors with well-defined structure,such as block copolymer,graft copolymer,star *** this review,we summarized the recent progress on intelligent hydrogels based on RAFT polymerization with emphasis on their fabrication strategies and applications for controlled drug delivery.

摘要：Objective： To provide essential information for peptide inhibitor design, the interactions of Eps15 homology domain of Eps15 homology domain-containing protein 1 （EHD1 EH domain） with three peptides containing NPF （asparagine-proline-phenylalanine）, DPF （aspartic acid-proline-phenylalanine）, and GPF （glycine-proline-phenylalanine） motifs were deciphered at the atomic level. The binding affinities and the underlying structure basis were investigated. Methods： Molecular dynamics （MD） simulations were performed on EHD1 EH domain/peptide complexes for 60 ns using the GROMACS package. The binding free energies were calculated and decomposed by molecular mechanics/ generalized Born surface area （MM/GBSA） method using the AMBER package. The alanine scanning was performed to evaluate the binding hot spot residues using FoldX software. Results： The different binding affinities for the three peptides were affected dominantly by van der Waals interactions. Intermolecular hydrogen bonds provide the struc- tural basis of contributions of van der Waals interactions of the flanking residues to the binding. Conclusions： van der Waals interactions should be the main consideration when we design peptide inhibitors of EHD1 EH domain with high affinities. The ability to form intermolecular hydrogen bonds with protein residues can be used as the factor for choosing the flanking residues.

摘要：In this paper, we present an ultrafast digitizer utilizing the DRS4 switched capacitor array applicationspecific integrated circuit to achieve an ultrafast sampling speed of at most 5 GS/s. We cascaded all eight channels(sub-channels) of a single DRS4 chip for increased storage depth. The digitizer contains four DRS4 chips, a quadchannel analog-to-digital converter,a controlling fieldprogrammable gate array, a PXI interface, and an SFP+connector. Consequently, each DRS4 channel has a depth of 8192 points and a vertical resolution of 14 bits. The readout sequences should be broken into several segments and then reordered to obtain the correct sequential data sets, and this offline procedure varies in different readout modes. This paper describes the design and implementation of the hardware;in particular, the respective processing procedures are described in detail. Furthermore, the offset error is calibrated and corrected to improve the precision of the captured waveform in both single-channel and highresolution modes.

摘要：Random Projection Code (RPC) is a mechanism that combines channel coding and modulation together and realizes rate adaptation in the receiving end. Random projection code’s mapping matrix has significant influences on decoding performance as well as hardware implementation complexity. To reduce hardware implementation complexity, we design a quasi-cyclic mapping matrix for RPC codes. Compared with other construction approaches, our design gets rid of data filter component, thus reducing chip area 7284.95 um2, and power consumption 331.46 uW in 0.13 um fabrication. Our simulation results show that our method does not cause any performance loss and even gets 0.2 dB to 0.5 dB gain at BER 10-4.

摘要：Sn-based electrocatalysts have been gaining increasing attention due to their potential contribution in the conversion of CO2 into HCOOH driven by sustainable energy sources;however,their actual capability to catalyze CO2 reduction reaction(CO2RR)still cannot meet the requirements of commercial-scale *** developing Snbased catalyst is of vital ***,the sheet-like heterophase Sn O2/Sn3O4 with a high density of phase interfaces has been first engineered by a facile hydrothermal process,with Sn3O4 as the dominant *** evidences from experiments and theoretical simulation indicate that the charge redistribution and built-in electric field at heterophase interfaces boost CO2 adsorption and HCOO*formation,accelerate the charge transfer between the catalysts and reactants,and ultimately greatly elevate the intrinsic activity of the heterophase Sn O2/Sn3O4 towards CO2 ***,the in-situ generated porous structure and metal Sn during CO2 RR improve the mass transmission within the interlayer volume and the conductivity of Sn O2/*** heterophase Sn O2/Sn3O4 displays high activity and selectivity for CO2 RR,achieving an improvement in CO2 reduction current density,88.3%Faradaic efficiency of HCOOH conversion at-0.9 VRHE,along with a long-term tolerance in CO2 *** study demonstrates that heterophase interface engineering is an efficient strategy to regulate advanced catalysts for different applications.

摘要：云南昆明筇竹寺五百罗汉造像是中国罗汉彩塑艺术的典型代表之一,是宗教佛理、民俗文化、艺术美感等多种文化熔铸合流的汇成之作。在我国动漫陷入严重同质化窠臼的当下,从筇竹寺五百罗汉造像的叙事性、形象性、戏剧性、民俗性、宗教性等方面,分析对当代动漫角色的剧本、形象、动作、色彩、内涵等方面所具有的启示意义,由此探求在数字媒体时代下动漫角色创作的新路径。

摘要：近年来,随着金融规制的解除、金融工具的进步,金融风险的性质及其累积速度发生了前所未有的改变,国际金融安全面临空前考验,世界各国构建或完善金融预警系统的任务迫在眉睫。本文主要介绍金融预警系统的核心——预警方法,文章从纵向和横向两方面介绍并比较了当代国外几种优良预警方法,并于文末指出了设计预警方法时应普遍注意的问题。

摘要：Polymer-mediated self-assembly of superparamagnetic iron oxide（SPIO） nanoparticles allows modulation of the structure of SPIO nanocrystal cluster and their magnetic properties. In this study, dopamine-functionalized polyesters（DApolyester） were used to directly control the magnetic nanoparticle spacing and its effect on magnetic resonance relaxation properties of these clusters was investigated. Monodisperse SPIO nanocrystals with different surface coating materials（poly（ε-caprolactone）, poly（lactic acid）） of different molecular weights containing dopamine（DA） structure（DA-PCL2k,DA-PCL1k, DA-PLA1k）） were prepared via ligand exchange reaction, and these nanocrystals were encapsulated inside amphiphilic polymer micelles to modulate the SPIO nanocrystal interparticle spacing. Small-angle x-ray scattering（SAXS）was applied to quantify the interparticle spacing of SPIO clusters. The results demonstrated that the tailored magnetic nanoparticle clusters featured controllable interparticle spacing providing directly by the different surface coating of SPIO nanocrystals. Systematic modulation of SPIO nanocrystal interparticle spacing can regulate the saturation magnetization（Ms） and T2 relaxation of the aggregation, and lead to increased magnetic resonance（MR） relaxation properties with decreased interparticle spacing.