摘要：The application-specific multiprocessor system-on-chip(MPSoC) architecture is becoming an attractive solution to deal with increasingly complex embedded applications,which require both high performance and flexible programmability. As an effective method for MPSoC development,we present a gradual refinement flow starting from a high-level Simulink model to a synthesizable and executable hardware and software specification. The proposed methodology consists of five different abstract levels:Simulink combined algorithm and architecture model(CAAM),virtual architecture(VA),transactional accurate architecture(TA),virtual prototype(VP) and field-programmable gate array(FPGA) emulation. Experimental results of Motion-JPEG and H.264 show that the proposed gradual refinement flow can generate various MPSoC architectures from an original Simulink model,allowing processor,communication and tasks design space exploration.

摘要：Synergistic therapy combines multiple therapeutic approaches in one shot,thus could significantly amplify the therapeutic ***,how to design the desirable combination to maximize the synergistic effect is still a big challenge in cancer ***,a nanoagent composed of glucose oxidase(GOx)and upconversion nanoparticles(UCNPs)were constructed for programmable starving-photodynamic synergistic cancer therapy through cascade glucose oxidation and hydrogen peroxide *** this nanoagent,GOx modulated the tumor glucose metabolism and consumed the β-D-glucose to produce *** glucose depletion induced"starvation"in cancer cells and caused cell ***,the generated H2O2 was photolyzed by the invisible ultraviolet emission of UCNPs under near-infrared light excitation at 980 *** toxic hydroxyl radicals produced by photolysis further induced cancer cell *** in vitro and in vivo experiments confirmed that this starving-photodynamic synergistic therapy significantly outran any single *** study paves an avenue to design programmable starving-photodynamic synergistic therapy for cancer management.

摘要：Accurate and fast performance estimation is necessary to drive design space exploration and thus support important design decisions. Current techniques are either time consuming or not accurate enough. In this paper, we solve these problems by presenting a hybrid method for multimedia multiprocessor system-on-chip （MPSoC） performance estimation. A general coverage analysis tool GNU gcov is employed to profile the execution statistics during the native simulation. To tackle the complexity and keep the analysis and simulation manageable, the orthogonalization of communication and computation parts is adopted. The estimation result of the computation part is annotated to a transaction accurate model for further analysis, by which a gradual refinement of MPSoC performance estimation is supported. The implementation and its experimental results prove the feasibility and efficiency of the proposed method.

摘要：The water-cooled ceramic breeder (WCCB) blanket is one of the blanket candidates for Chinese fusion engineering testing reactor (CFETR) and is being developed at the Institute of Plasma Physics, Chinese Academy of Sciences (ASIPP). This paper reviews design and evolution of the WCCB blanket for CFETR, and presents a new WCCB blanket design according to the latest CFETR core parameters (major and minor radii are R = 7.2 m and a = 2.2 m, respectively) and missions. This new design is expected to satisfy multiple CFETR operation modes of 0.2, 0.5, 1.0, and 1.5 GW fusion power and achieve tritium self-sufficiency. The feasibility of the updated blanket design is evaluated from the aspects of neutronics and thermo-hydraulics. Furthermore, the research and development (R&D) activities supporting to the WCCB blanket for CFETR are reported, including the design code, the water loop experiments, the pebble bed modeling and experiments, and the components fabrication technology.

摘要：Oxygen electrocatalysis,exemplified by the oxygen reduction reaction(ORR)and oxygen evolution reaction(OER),is central to energy storage and conversion technologies such as fuel cells,metal-air batteries,and water ***,highly effective and inexpensive earth-abundant materials are sought after to replace the noble metal-based electrocatalysts currently in ***,metal-organic frameworks(MOFs)and carbon-based MOF derivatives have attracted considerable attention as efficient catalysts due to their exceedingly tunable morphologies,structures,compositions,and ***,we report two-dimensional(2D)MOF/MOF derivative coupled arrays on nickel foam as binder-free bifunctional ORR/OER catalysts with enhanced electrocatalytic activity and *** remarkable electrochemical properties are primarily attributed to fully exposed active sites and facilitated charge-transfer *** coupled and hierarchical nanosheet arrays produced via our growth-pyrolysis-regrowth strategy offer promise in the development of highly active electrodes for energy-related electrochemical devices.

摘要：针对现有果园液态肥深施技术装备无法满足果树个性化养分需求的问题,设计一种果园多养分精准配肥变量注肥机控制系统。该系统使用三个蠕动泵分别供给氮、磷、钾液态肥料,根据精准施肥决策处方,在混合箱中形成多养分肥料;采用液压驱动旋转钻入土壤,基于位移传感器数据反馈,精准控制钻孔深度;多养分肥料在注肥泵的作用下,经中空的注肥杆从底部小孔注入土壤。开发控制算法和交互式界面,标定蠕动泵的单圈排肥量,构建深度与位移传感器信号值之间的映射关系。通过性能测试,得到肥料供给量的相对误差小于2%,钻孔深度的相对误差小于15%,可以满足要求。该系统实现现场精准配制多养分肥料,满足果树个性化养分需求。

摘要：锂离子电池(LIBs)因其高能量密度、长寿命和低成本等优点,已广泛应用于储能领域。由于正负极在循环过程中发生周期性体积变化,电池产生应力和应变累积,而应变演变与电池的荷电状态(SOC)密切相关。因此,实时监测电池的应变变化对于电池的长期安全稳定运行至关重要。因此,本文采用光纤布拉格光栅(FBG)传感器对石墨-磷酸铁锂(AG||LFP)软包电池进行了应变监测。设计了光纤与电池及电极片的结合方式,原位监测了各电极以及电池整体的应变演化,并分析了软包电池中应力的成因。进一步地,基于应变量对AG||LFP软包电池的SOC进行了估计,展示了FBG传感器在电池荷电状态监测中的潜力。

摘要：针对轨道交通内置式永磁同步电机受IGBT开关频率限制难以实现高性能无感控制的问题,设计了一种基于龙贝格观测器的无位置传感器矢量控制。将电机电压方程改为基于扩展反电势的全阶模型,在此基础上进行龙贝格观测器的设计,从理论上分析了系统的稳定性,并给出参数设计方法。为了适应低开关频率应用环境,将观测器模型进行四阶离散化设计,以提高观测器的精度。以一台永磁同步电机作为控制对象,采用设计的无位置传感器控制进行试验验证。试验结果表明,设计的基于龙贝格观测器的无位置传感器控制转矩控制精度在2%以内,并且系统具有良好的负载突变动态特性。

摘要：无为剔墨纱灯为安徽省传统技艺类非物质文化遗产,具有鲜明的艺术特色和独特的工艺特征。但在生产组织、创意设计和推广方式等方面还存在与当代社会脱节的现象。为更好地将这种传统手工技艺传承与开发,本文从设计策略、分工协作、文化体验等方面提出解决路径。

摘要：背景与目的乏氧是实体肿瘤的一个重要生物学特征,组织乏氧导致肿瘤对放疗和化疗不敏感,从而增加其对放化疗的抵抗性,因此确定肿瘤组织乏氧程度具有重要意义。核医学乏氧显像能够反映肿瘤组织乏氧程度,他能选择性地滞留在乏氧细胞或组织中,主要包括硝基咪唑类和非硝基咪唑类;其中硝基咪唑类肿瘤乏氧细胞显像剂是国内外研究的较多并且具有发展前景的一类用于肿瘤治疗的药物。本研究应用放射性核素标记技术对研制具有临床应用价值的肿瘤乏氧显像剂乙二胺四乙酸-甲硝唑酯(ethylenediaminetetraacetic acid-metronidazole,EDTAMN)配体进行标记。探讨采用氯化亚锡还原法法进行99mTc标记的可行性,评价99mTc-EDTA-MN的放化特性,观察99mTc-EDTA-MN在非小细胞肺癌(non-small cell lung cancer,NSCLC)裸鼠模型体内的生物学分布特点,为其进一步研究与应用提供实验依据。方法采用氯化亚锡还原法进行EDTA-MN配体的99mTc标记,分别对反应量(10 mg、5 mg、2 mg)、氯化亚锡用量(8 mg/m L、4 mg/m L、2 mg/m L)、标记体系p H(2、4、5、6)逐一进行试验,采用正交试验设计进行分析,以寻找最佳标记条件。采用纸层析法和高效液相色谱法测定标记率、放化纯度、脂水分配系数及室温下在生理盐水的体外稳定性,并对标记物在裸鼠体内的生物学分布进行初步显像研究。结果最佳标记条件下的标记率(84.11±2.83)%,放射化学纯度大于90%,室温下放置12 h在生理盐水中较稳定。脂水分配系数为lg P=-3.05。尾静脉注射99mTc-EDTA-MN的3 h内,裸鼠肿瘤模型初步显像示0.5 h时膀胱区域见大量放射性浓聚,1 h时肿瘤显影清晰,其余脏器内放射性分布均较低。采用ROI技术测得0.5 h、1 h、2 h、3 h肿瘤部位单位面积内放射性计数(88.14±11.59)、(123.17±9.06)、(98.08±14.40)和(79.87±10.57),并计算肿瘤与肝脏区域的T/NT比值分别为(1.95±0.19)、(3.58±0.78)、(3.95±0.39)和(5.01±0.28)。结论 99mTc-EDTA-MN易于制备具有比较理想的体内分布动力学特性,可满足后续进一步的体内、外实验研究。