摘要：Miniature devices comprising stimulus-responsive hydrogels with high environmental adaptability are now considered competitive candidates in the fields of biomedicine,precise sensors,and tunable *** and advanced fabricationmethods are critical formaximizing the application capabilities ofminiature ***-based three-dimensional(3D)printing technology offers the advantages of a wide range of applicable materials,high processing accuracy,and strong 3D fabrication capability,which is suitable for the development of miniature devices with various *** paper summarizes and highlights the recent advances in light-based 3D-printed miniaturized devices,with a focus on the latest breakthroughs in lightbased fabrication technologies,smart stimulus-responsive hydrogels,and tunable miniature devices for the fields of miniature cargo manipulation,targeted drug and cell delivery,active scaffolds,environmental sensing,and optical ***,the challenges in the transition of tunable miniaturized devices from the laboratory to practical engineering applications are *** opportunities that will promote the development of tunable microdevices are elaborated,contributing to their improved understanding of these miniature devices and further realizing their practical applications in various fields.

摘要：Cu pillar bump offers a number of advantages for flip chip packaging,compared to the conventional solder ***,due to its rigidity structure,Cu pillar bump introduces a lot of stress to the chip,which causes the failure of packaging structures,especially for the advanced node devices which typically have brittle low K dielectric *** this paper,for the first time we propose two types of Cu pillar structures to reduce the *** first Cu pillar structure has bigger Cu dimensions at the *** other one is designed to add an additional Cu pad under the Cu pillar *** element analysis is used to study the stress of the both structures,and it is found that with the increase in pillar bump contact area over the chip surface,the stress decreases in both *** also indicate that the Cu pillar bump undercut induces higher stress,and thin Cu6 Snss intermetallic compound has less impact on the stress during flip chip mount *** study provides a novel way to improve the reliability by reducing the stress in the Cu pillar bump related packaging.

摘要：Networked control system is new hot-point in control engineering. A new delayed model for networked control systems is presented, based on which an LQR controller is designed. A method of delays estimation online is also given. For the difficulty on implementation of LQR in NCSs with time-variant delays, the Mamdani intelligent logic with LQR controller is addressed. The stability of the networked control system is also given. Simulation results prove that the novel controller can make the system stable and robustly preserve the performance in terms of time-variant delays.

摘要：Multi-wall carbon nanotube filled shape memory polymer composite(MWCNT/SMC)possessed enhanced modulus,strength,and electric conductivity,as well as excellent electrothermal shape memory properties,showing wide design scenarios and engineering application *** thermoelectrically triggered shape memory process contains complex multi-physical mechanisms,especially when coupled with finite deformation rooted on micro-mechanisms.A multi-physical finite deformation model is necessary to get a deep understanding on the coupled electro-thermomechanical properties of electrothermal shape memory composites(ESMCs),beneficial to its design and wide *** into consideration of micro-physical mechanisms of the MWCNTs interacting with double-chain networks,a finite deformation theoretical model is developed in this work based on two superimposed network chains of physically crosslinked network formed among MWCNTs and the chemically crosslinked *** intact crosslinked chemical network is considered featuring with entropic-hyperelastic properties,superimposed with a physically crosslinked network where percolation theory is based on electric conductivity and electric-heating *** model is calibrated by experiments and used for shape recoveries triggered by heating and electric *** captures the coupled electro-thermomechanical behavior of ESMCs and provides design guidelines for MWCNTs filled shape memory polymers.

摘要：六次产业化是乡村产业发展的必然趋势,是推动乡村高质量发展的重要路径和有效抓手。从分析六次产业化的内涵入手,探寻设计赋能乡村六次产业的基本逻辑和演化机制;从“设计乡村化和乡村设计化”双路径赋能机制和“设计介入-产业协同-融合共生”三个赋能维度,探索设计赋能的运行方式;构建一个包含资源支撑、设计驱动、制度保障的理论框架,提出乡村设计实践可以通过“一个框架、一个体系和一套制度”来实现设计赋能,并以农产品包装设计和非遗信息图形设计为案例进行实证分析。指出设计驱动产业融合创新,可促进乡村“三产融合、两化融合、全域融合”,赋能优质资源不断转化为乡村永续发展动能,促进乡村六次产业发展,更好地服务于乡村产业兴旺和高质量发展。

摘要：立足国家创新战略发展需求,从教学设计、教学目标、教学内容、教学模式和方法、第二课堂和考核评价方式等方面对有机化学课程进行改革,将其打造为优质课程思政的阵地。以创新国家战略需求对有机化学的要求为主线,构建课程思政体系及典型案例。在课程实践上,引导学生主动学习、深度思考、互相交流,组织学生积极参与和体验,极大地提升了学生学习有机化学的“获得感”,夯实学生的专业知识和能力素养的同时,也融入了思想教育元素,助力创新国家战略下的有机化学行业人才培养,可为其他化学基础课程开展课程思政育人提供参考。

摘要：Empirical research is playing a significant role in software engineering （SE）, and it has been applied to evaluate software artifacts and technologies. There have been a great number of empirical research articles published recently. There is also a large research community in empirical software engineering （ESE）. In this paper, we identify both the overall landscape and detailed implementations of ESE, and investigate frequently applied empirical methods, targeted research purposes, used data sources, and applied data processing approaches and tools in ESE. The aim is to identify new trends and obtain interesting observations of empirical software engineering across different sub-fields of software engineering. We conduct a mapping study on 538 selected articles from January 2013 to November 2017, with four research questions. We observe that the trend of applying empirical methods in software engineering is continuously increasing and the most commonly applied methods are experiment, case study and survey. Moreover, open source projects are the most frequently used data sources. We also observe that most of researchers have paid attention to the validity and the possibility to replicate their studies. These observations are carefully analyzed and presented as carefully designed diagrams. We also reveal shortcomings and demanded knowledge/strategies in ESE and propose recommendations for researchers.

摘要：This paper is based on the fieldwork in Xishuang-banna Natioanl Nature Reserve in Yunnan Province of *** data of Asian elephants were collected and analyzed with the remote sensing satellite photos of the region to estimate the landform physiognomy of different *** also analyzed a series of ecological factors includ-ing altitude,landform,relief,villages and roads which affected the distribution and movement of Asian *** results suggested the possibility of designing and estab-lishing corridors in Xishuangbanna National Nature Reserve to protect the population of wild elephants in the region.

摘要：Based on the similarities in the conformation of VS008（N-（4-methylphenyl）-3-（tert-butyl）-1-（phenylmethyl）-1H-pyrazole-5-carboxamide） and BYIO6830（N＇-（3,5-dimethylbenzoyl）-N＇-tert-butyl-5-methyl-2,3-dihydro-l,4-benzodioxine-6-carbohydrazide） bound to the active site of the EcR subunit of the ecdysone receptor（EcR）-ultraspiracle protein（USP） heterodimeric receptor,a series of new pyrazole amide derivatives were designed and *** structures were confirmed by IR,~1H NMR,^（13）C NMR and elemental *** from a preliminary bioassay revealed that two of the pyrazole derivatives exhibited promising insecticidal ***,compounds 6e and 6i exhibited good activity against Helicoverpa armigera（cotton bollworm） at low *** displayed by tebufenozide-treated *** were identical with those displayed by its treated counterpart.6i showed the same poisoning symptoms as those of *** addition,results from molecular docking result indicated that the binding modes of 6e and 6i at the active site of the EcR subunit of the heterodimeric receptor were similar to that of the bound tebufenozide.

摘要：In order to discover highly active ecdysone analogs, a series of new substituted pyrazole amide derivatives were obtained using structure-guided optimization method and further screened for their insecticidal activities, in the basis of the core structures of the two active compounds N-（3-methoxyphenyl）-3-（tert-butyl）-1-phenyl-1H-pyrazole-5-carboxamide（6e） and N-（4-（tert-butyl）phenyl）-3-（tert-butyl）-1-phenyl-1H-pyrazole-5-carboxamide（6i）, previously presented by us. The chemical structures of the title compounds were identified by spectral analyses. The preliminary bioassay results indicated that one among the synthesized pyrazole derivatives, compound 34, endowed with good activity against Mythimna Separata at 10 mg/L, which was equal to that displayed by the positive control tebufenozide. In addition, examples of molecular docking and molecular dynamics studies demonstrated that 34 may be the potential inhibitor to Ec R and its docking conformation was similar to that of tebufenozide. In addition, increasing the hydrophobic effect and considering the suitable bulk effect on pyrazole ring are beneficial to the inhibiting activity to Ec R and activity in vivo.