摘要：In this study, the authors developed a new irrigation scheme based on the Noah land surface model, and then coupled it with the Weather Research and Forecasting regional climate model. Two simulations （with and without irrigation） were conducted over the Yellow River basin for the period April to October 2000-2010. The results indicated that the WRF model is able to successfully capture the spatial pattern and seasonal changes in observed temperature and precipitation over the Yellow River basin. When irrigation was induced, the mean surface air temperature at 2 m （T2m） decreased by 0.1-0.4 K, and there was a correspond increase （decrease） in latent （sensible） heat flux over the irrigated areas, wherein the increase （decrease） reached more than 10 W m-2 over the largest irrigated areas. The cooling effect was consistent with the changes in evapotranspiration and heat fluxes due to *** changes in lifting condensation level and planetary boundary layer height led to a greater probability of cloud formation and bore a close association with surface fluxes and soil moisture, which then impacted the spatial distribution of T2rn and precipitation.

摘要：装配式建筑的关键问题是连接,因此,为了解现浇与套筒不同连接方式对陶粒混凝土复合墙板节点抗震性能的影响规律,本文设计了3个现浇构件和1个装配式套筒连接构件。此类构件保温隔热性能良好,解决了外墙保温板易脱落问题。通过低周反复试验分别研究了构件的破坏模式、滞回及骨架曲线、承载能力、刚度、耗能、残余变形等抗震性能。结果表明:两类构件的破坏区域主要发生在翼缘板和腹板上,尤其是在腹板脚部的混凝土被拉裂或压碎,钢筋被拉长或压弯;构件的节点核心区相对完好,符合“强节点,弱构件”设计要求,破坏模式均属于弯剪破坏。装配式套筒连接构件的正负向峰值荷载与现浇构件相比分别提升了12.71%和4.95%,承载力表现相对良好。套筒连接构件的整体刚度曲线高于现浇构件,初始刚度与现浇构件相比提高了7.53%,抗侧刚度明显加强。套筒连接方式在加载后期能较好地减小墙板构件的残余变形,可恢复性能好;两类构件的强度退化曲线较接近,强度变化相对稳定;套筒连接构件和现浇构件的强度退化系数及曲线发展趋势相似,两类构件基本能等同。因此,陶粒混凝土复合墙板节点采用套筒连接方式有效,整体工作性能良好,可为此类构件在实际工程中的应用提供参考。

摘要：病历的打印是临床工作的实际需要,电子病历的续打是电子病历的技术难点之一。续打是指一张病历纸可以打印多遍,后一遍仅打印该页的新增内容。利用VBA在Word中二次开发实现了电子病历的续打功能。

摘要：目的设计检测多个靶基因的炭疽多重荧光定量PCR反应系统,建立快速准确的基因诊断方法,解决蜡样芽胞菌群基因诊断交叉反应问题。方法选择炭疽杆菌PX01毒素质粒基因pagA,PX02毒素质粒基因capB,以及染色体上的前噬菌体λBa03基因PL3作为靶基因,利用在线荧光定量PCR引物设计软件设计、优化多重PCR引物以及相应的Taqman探针序列,对探针进行LNA标记并优化荧光PCR反应体系,构建多重实时荧光定量PCR反应系统。以3对引物PCR扩增并克隆靶基因的质粒标准品,倍比稀释后进行敏感度试验,以炭疽、蜡样芽胞杆菌、苏云金杆菌、蕈状杆菌以及常见肠道致病菌进行特异度试验,利用炭疽弱毒株污染土壤及奶粉进行模拟检测。结果 Taqman-LNA多重实时荧光定量PCR可迅速检出3个炭疽杆菌靶基因,常用的探针法荧光定量PCR反应液均适用;pagA、CapB、PL3基因克隆标准品序列正确;该方法对pagA、CapB、PL3基因的检出限分别为63、398、114copies/μl,且仅检出炭疽杆菌基因,其余4种蜡样芽胞菌扩增均阴性。土壤及奶粉样品检测均阳性,其中pagA近检出限为6.6×104/ml,PL3基因检出限为6.6×105/ml。结论 Taqman-LNA多重实时荧光定量PCR方法具有适用性广,检测迅速,灵敏度及特异度高等特点,能够将炭疽杆菌与蜡样芽胞菌群中其他细菌相鉴别,可试用于炭疽杆菌的感染检测。

摘要：Herein,we report a geometrically well-defined prism assembled by two floxuridine(F)integrated RNA strands as a precise nanomedicine for chemodrug *** to the similarity between chemotherapeutic F and uridine(U),all uridines in the component RNA strands are replaced by F during their in vitro transcription *** specifically designing their sequences,F-containing S-shape tiles with the single-stranded loops are constructed and then further assemble into the RNA prism through T-junction interactions and sticky-end *** present study demonstrates that the F-integrated RNA prism can serve as an efficient platform for chemodrug delivery and anticancer *** believe that the study would help the future development of RNA-based nanomedicine in various applications.

摘要：TiO2 pigments are typically coated with inert layers to suppress the photocatalytic activity and improve the weatherability. However, the traditional inert layers have a lower refractive index compared to TiO2, and therefore reduce the lightening power of TiO2. In the present work, a uniform, amorphous, 2.9-nm-thick TiO2 protective layer was deposited onto the surface of anatase TiO2 pigments according to pulsed chemical vapor deposition at room temperature, with Ti Cl4 as titanium precursor. Amorphous TiO2 coating layers exhibited poor photocatalytic activity, leading to a boosted weatherability. Similarly, this coating method is also effective for TiO2 coating with amorphous SiO2 and SnO2 layers. However, the lightening power of amorphous TiO2 layer is higher than those of amorphous SiO2 and SnO2 layers. According to the measurements of photoluminescence lifetime, surface photocurrent density, charge-transfer resistance, and electron spin resonance spectroscopy, it is revealed that the amorphous layer can prevent the migration of photogenerated electrons and holes onto the surface, decreasing the densities of surface electron and hole, and thereby suppress the photocatalytic activity.

摘要：针对复杂产品的设计需求,深入分析了复杂产品的建模过程.基于参数化建模和多学科优化思想,建立了复杂产品综合优化设计的理论框架.其中,设计结构树存储了复杂产品从整机直到零件级结构信息;基于数据库协调的多学科协同寻优策略可以得到复杂产品的综合优化解.阐述了基于面向对象技术开发的数据库功能体系,该体系既保证了设计结构树中有效数据的存储,也为多学科协同寻优定义了相关操作.在实践应用上,开发了水轮发电机综合优化设计软件平台,应用实例验证了理论和实际研究工作的有效性和可行性.

摘要：Backfill mining is one of the most important technical means for controlling strata movement and reducing surface subsidence and environmental damage during exploitation of underground coal resources. Ensuring the stability of the backfill bodies is the primary prerequisite for maintaining the safety of the backfilling working face, and the loading characteristics of backfill are closely related to the deformation and subsidence of the roof. Elastic thin plate model was used to explore the non-uniform subsidence law of the roof, and then the non-uniform distribution characteristics of backfill bodies’ load were revealed. Through a self-developed non-uniform loading device combined with acoustic emission (AE) and digital image correlation (DIC) monitoring technology, the synergistic dynamic evolution law of the bearing capacity, apparent crack, and internal fracture of cemented coal gangue backfills (CCGBs) under loads with different degrees of non-uniformity was deeply explored. The results showed that: 1) The uniaxial compressive strength (UCS) of CCGB increased and then decreased with an increase in the degree of non-uniformity of load (DNL). About 40% of DNL was the inflection point of DNL-UCS curve and when DNL exceeded 40%, the strength decreased in a cliff-like manner;2) A positive correlation was observed between the AE ringing count and UCS during the loading process of the specimen, which was manifested by a higher AE ringing count of the high-strength specimen. 3) Shear cracks gradually increased and failure mode of specimens gradually changed from “X” type dominated by tension cracks to inverted “Y” type dominated by shear cracks with an increase in DNL, and the crack opening displacement at the peak stress decreased and then increased. The crack opening displacement at 40% of the DNL was the smallest. This was consistent with the judgment of crack size based on the AE b-value, i. e., it showed the typical characteristics of “small b-value-large crack and

摘要：应用S1,S2流面理论对某大型液氢/液氧火箭发动机涡轮泵的两级轴流式涡轮内部跨声速流场进行计算和分析。流面的求解采用流线曲率法。将混合平面法的思想用于流线曲率法的求解过程中,对动、静叶排之间的相互干扰进行处理,将复杂的非定常问题简化为定常问题,从而简化计算。粘性的影响通过几种损失系数进行修正。计算结果较好地描述了涡轮内部的流动情况,为进一步完善涡轮设计、提高涡轮性能提供了理论依据。

摘要：针对航天器姿态跟踪控制的快速性需求,提出一类自适应终端滑模有限时间控制方法,通过引入饱和函数解决了终端滑模控制器的奇异问题,并结合实际有限时间稳定概念显式地给出了系统状态收敛时间和收敛范围之间的对应关系;为在提高系统鲁棒性的同时避免控制器抖振,设计了一种新型自适应律估计并补偿未知环境干扰。进一步地,针对如遥感卫星对地扫描成像等姿态跟踪任务中存在的状态约束问题,通过在控制器中引入具有对数形式的预设性能项,使系统滑模面响应具有期望的动态过程,约束了航天器姿态跟踪误差及其一阶导数的变化范围。仿真结果表明,设计的控制器具有较高的控制精度和响应速度,满足实际任务对状态约束的需求,且其控制输出不存在奇异和抖振,具备良好的工程应用价值。