摘要：你如果去美发沙龙,会有人帮你洗头发,然后再由另一个人帮你剪发、设计发型或者染发,这个人就是发型师。每一位发型师都需要接受训练。大多数人都会先读完高中,然后去上一年或十四个月的美发学校。

摘要：Value delivery is becoming an important asset for an organization due to increasing competition in industry. Therefore, companies apply Agile Software Development (ASD) to be more competitive and reduce time to market. Using ASD for the development of systems implies that established approaches of Requirements Engineering (RE) undergo some changes in order to be more flexible to changing requirements. To this end, the field of agile RE is emergent and different process models for agile RE have arisen. The aim of this paper is to build an abstract layer about the variety of existing process models by means of a metamodel for agile RE. It has been created in several iterations and relies on the evaluation of related process models. Furthermore, we have derived process models for agile RE in industry by presenting instances of the metamodel in two different cases: one is based on Scrum whereas the other is based on Kanban. This paper contributes to the software development body of knowledge by delivering a metamodel for agile RE that supports researchers and practitioners modeling and improving their own process models. We can conclude that the agile RE metamodel is highly relevant for the industry as well as for the research community, since we have derived it following empirical research in the field of ASD.

摘要：本案位于伦敦Kensington—条绿树成荫的宁静道路上,建筑原为维多利亚式的连栋房屋。伦敦建筑事务所FLOW Architecture和Magrits共同完成了该住宅项目的改造与扩建工作。设计团队不仅对这栋建于1851年的四层排屋进行了彻底的空间改造,并在此基础上,增加了一个地下室和一个位于住宅后端的两层高的延伸空间。

摘要：项目坐落于西班牙马略卡岛的首府帕尔马,是一个极简抽象派风格的度假屋。该度假屋巧妙地融合了斯堪的纳维亚和地中海美学,对位于一块狭长土地上的传统联排别墅进行彻底翻新。尽管该住宅外形细长,但设计团队仍确保室内能够获得足够的采光。该设计方案利用了大部分的自然光,将起居室布局在该狭长土地的末端,靠近天井,大面的推拉落地窗使得整个房子充满自然光线。

摘要：本案是中国领先的科技公司——小米在巴西设立的新分部办公室,由圣保罗ARKIZ建筑事务所担纲室内总设计。追求高效和注重环保的设计方式正是小米选择和看重ARKIZ建筑工作室的原因。设计团队利用各种有趣的材料进行分区,在和谐、统一的空间中,打造出独特、美观、实用,同时让人放松和愉悦的办公环境。

摘要：非同质化代币(NFTs)是代表艺术品、收藏品和游戏内道具等物品的数字资产。它们往往使用加密货币进行在线交易,通常在区块链上的智能合约中进行编码。2021年,NFTs的市场销量创下了历史最高纪录,公众对NFTs的关注度激增,但其市场的整体结构和演变却鲜为人知。本文中,我们分析了2017年6月23日至2021年4月27日470万NFTs的610万笔交易数据,这些数据主要来自以太坊和WAX区块链。首先,我们描述了市场的统计特征。其次,我们构建了交互网络,表明交易者通常专注于与类似对象相关的NFTs,并与交换同类对象的其他交易者形成紧密的集群。再次,我们根据NFTs的视觉特征对其关联的对象进行聚类,并表明集合包含视觉上同质的对象。最后,我们使用简单的机器学习算法研究NFT的可预测性,发现其销售历史、视觉特征是价格的良好预测因素。我们期望这些发现能够促进在不同背景下对NFT生产、采用和交易的进一步研究。

摘要：All living organisms share similar reactions within their central metabolism to provide precursors for all essential building blocksand reducing power. To identify whether alternative metabolic routes of glycolysis can operate in E. coli, we complementarilyemployed in silico design, rational engineering, and adaptive laboratory evolution. First, we used a genome-scale model andidentified two potential pathways within the metabolic network of this organism replacing canonical Embden-Meyerhof-Parnas(EMP) glycolysis to convert phosphosugars into organic acids. One of these glycolytic routes proceeds via methylglyoxal andthe other via serine biosynthesis and degradation. Then, we implemented both pathways in E. coli strains harboring defectiveEMP glycolysis. Surprisingly, the pathway via methylglyoxal seemed to immediately operate in a triosephosphate isomerasedeletion strain cultivated on glycerol. By contrast, in a phosphoglycerate kinase deletion strain, the overexpression ofmethylglyoxal synthase was necessary to restore growth of the strain. Furthermore, we engineered the “serine shunt” whichconverts 3-phosphoglycerate via serine biosynthesis and degradation to pyruvate, bypassing an enolase deletion. Finally, toexplore which of these alternatives would emerge by natural selection, we performed an adaptive laboratory evolution studyusing an enolase deletion strain. Our experiments suggest that the evolved mutants use the serine shunt. Our study reveals theflexible repurposing of metabolic pathways to create new metabolite links and rewire central metabolism.

摘要：本项目位于葡萄牙中南部的格兰杜拉小镇,建筑所在的场地非常开阔,周遭只有零星的乔木和灌木。建筑采用石灰砂浆砌筑,并在外部增加软木保温层,通体的暖色调与土地的颜色相近,远远看去仿佛与周围环境融于一体。建筑的主入口位于北侧,几块极简的几何体共同构成了2层的建筑体量。当从南侧看向建筑时,在视觉上只显示有1层建筑体量,这是由于建筑师利用南北侧的高差将部分空间“隐藏”于场地内。住宅的主要功能区位于上层空间,包括客厅、厨房及餐厅等。建筑东西两端各有一个半室外空间,不同方向的开窗可以引入不同的景色,在阳光照射下,移动的光影形成丰富的视觉效果。位于建筑中央的天井是一处休闲空间,这里光照充沛,并可通过开窗的立面,将日光由此引入内部走廊,以增强室内外空间的联系。此外,建筑师在建筑的北侧,沿墙打造了一处水池,波光粼粼的水面减弱了建筑整体的粗犷感,也丰富了场地内的景观。

摘要：Introduction: Women’s sexual function is a complex ensemble of variables that involve physical, emotional, and psychosocial states. Objective: This review aims to evaluate the evidence about the sexual behavior of women during pregnancy. Methods: Survey of PubMed for the period from 1996 to 2011 for prospective, retrospective and case-control studies, randomized clinical trials, meta-analyses and systematic reviews on the sexual function of women during pregnancy using the terms “sexual function”, “sexual dysfunction”, “sexuality”, “pregnancy”, and “pregnant woman”. Results: Changes occur in the sexual function of women during pregnancy;however, due to the heterogeneity of the studies and the incomparability of samples for lack of pairing for cultural, age, length of relationship and gestational age variables, and other methodological biases, it is not possible to characterize the sexual response of pregnant women. Conclusions: The changes observed are not sufficient to characterize sexual behavior during pregnancy as pathological. It is therefore necessary to standardize the study groups and the instruments for the assessment of sexual function, to determine the presence of distress concomitant with changes in sexual function, and to assess the sexual function of the partner and the impact of changes on the dyadic relationship before and after the gestational period.

摘要：人性真实的互动、情感的交流能为企业衍生出良好的社交网络与带来更多的商业机会.我们让办公室中会发生的一切人、事、物聚集到同一个空间中,让员工们在任何时刻、任何地方都能轻松分享彼此的想法和价值观,以比较放松自在的会面聊天来拉近员工之间的工作关系,甚至是激发出各种创新的可能,让他们对此空间产生团体共享的责任以及维护感,进而促成人们与空间合为一体的感觉,而这就是我们在高雄共同工作空间所创造出的价值所在.