摘要：Animal models have been extensively used in cancer pathology studies and drug *** models,however,fail to reflect the complex human tumor microenvironment and do not allow for high-throughput drug screening in more human-like physiological ***-dimensional(3D)cancer models present an alternative to automated high-throughput cancer drug discovery and *** this review,we highlight recent technology innovations in building 3D tumor models that simulate the complex human tumor microenvironment and responses of patients to *** discussed various biofabrication technologies,including 3D bioprinting techniques developed for characterizing tumor progression,metastasis,and response to treatment.

摘要：A gallium nitride(GaN)power amplifier monolithic microwave integrated circuit(MMIC)with a wide band and high efficiency in the microwave frequency band is proposed in this *** power amplifier MMIC uses a 0.15^im GaN high electron mo-bility transistor(HEMT)*** operating frequency band of the amplifier can cover the whole K-band,i.e.,17-26.5 GHz.

摘要：有机电合成是一种绿色、温和、高效的合成方法,但其在本科有机实验教学中并未有效推广。二氢苯并噻吩衍生物广泛存在于生物活性化合物中,在医药行业有重要的应用价值。对苯并噻吩衍生物进行加氢还原是获得该类化合物最简单直接的方法,但传统的还原方法存在诸多缺陷。最近,我们建立了一种电化学促进的苯并噻吩衍生物的还原方法,该方法以电子作为还原剂,六氟异丙醇作为氢供体。在此基础上,设计了一个对苯并噻吩砜进行电化学还原制备2,3-二氢苯并[b]噻吩1,1-二氧化物的有机化学实验。

摘要：Studies on beam optics and the isocenter property in the gantry system for the SC200(Superconducting Isochronous Cyclotron of 200 Me V in Hefei,China) are presented in this *** physical design of the isocentric gantry system is developed with the software TRANSPORT,which realizes a beam with a circular shape at the isocenter and a full width at half maximum of4–10 *** stereotactic radiosurgery,the isocenter deviation of the gantry system should be less than 1 mm in *** order to explore the property of the isocenter,an electromagnetic structure coupling analysis has been conducted given the self-gravity and the electromagnetic(EM) force of the magnets on the gantry beam *** correlation between the isocenter property and the EM force has also been carefully *** paper puts forward two methods to obtain the isocenter deviation based on the characteristics of the nozzle installation structure and the calculation of the optical path after the nozzle,*** results show that the maximum isocenter deviation is less than 0.33 mm with a safety factor of 1.5,and the deviation caused by the EM force is 0.05 *** latter result indicates that the impact of the EM force is *** paper puts forward one possible way to realize real-time acquisition of the isocenter deviation in practical *** gantry of SC200 is under construction at ASIPP.

摘要：Space information network is used for real time acquiring, transmitting and processing the space information on the space platform, which provides significant communication services for communication, navigation positioning and science exploration. In this paper, the architecture of Software Defined Space Optical Network (SDSON) based on cloud platform is designed by means of Software Defined Optical Network (SDON) and cloud services. The new architecture combining centralized and distributed management-control mechanism is a multi-layer and multi-domain architecture with powerful computing and storage ability. Moreover, reliable service and unreliable service communication models employed in the space information network are proposed considering the characteristic of Disruption/Delay Tolerant Network (DTN). Finally, the functional verification and demonstration are performed on our optical experimental network platform.

摘要：Shape memory materials possess programmable complex and large deformations towards external stimuli,which are particularly essential for their potential *** the transformation of planar two-dimensional(2D)structures into complex 3D structures,the design of asymmetric or bilayer thin sheets is usually *** this paper,we propose a facile strategy to achieve these complex 3D structures that can be transformed to various pre-determined shapes sequentially by laser-triggered site-specific *** response of shape memory polycaprolactone(PCL)to laser is realized by physically dopingW18O49 nanowires into the cross-linked PCL diacrylate *** irradiated by 98 mW cm^(−2)laser,the pre-stretched PCL/W_(18)O_(49)film shows an out-of-plane bending deformation due to the temperature gradient and single-domain orientation on the thickness between the upper layer and lower *** bending rates and amplitudes of the film can be tailored by adjusting the parameters of irradiation time,the film thickness as well as the pre-stretch ***,the pre-stretched film can automatically bend in more intricate complex deformations by integration with kirigami cuts in ***,we demonstrate that by activating the dynamic transesterification reaction within the same film,it can also achieve the 2D-to-3D *** these decent features,this kind of novel PCL//W_(18)O_(49)film shows great potential in the field of biomedical devices or soft robotics.

摘要：电感耦合等离子体(ICP)光谱仪是一种应用范围很广的元素分析仪,主要用于元素定性与定量的分析。ICP光源是光谱仪的核心部件,它在光谱仪中扮演着至关重要的角色。目前主流的ICP光源有两种:自激式和他激式,各自具有优缺点。他激式光源电路复杂、体积庞大、阻抗匹配速度较慢、最大输出功率有限。设计了一种基于镀金工艺的高功率MOSFET和变频实现阻抗匹配的自激式ICP光源,该光源采用射频放大和阻抗匹配一体化的设计,把从负载线圈采样的频率信号f_(1)以及功率放大电路放大后的频率相位f_(0)进行相位比较,再根据两者相位差的变化,进而控制频率的变化,实现阻抗匹配;设计上采用了镀金工艺的金属化硅N通道型高功率的MOSFET实现功率放大,具有更大的功率密度、更小的体积,最大输出功率超过2400 W。对研制的ICP光源进行了电学静态测试,给出了鉴相器、压控振荡器以及功率的输出特性,验证了各电路在相应工作状态下的性能表现;同时结合光谱仪进行了包含Ba、Na和li元素标准溶液的测试,获得了目标元素的光谱信号;另外,对获得的光谱信号进行了处理,使用了基于EEMD特征增强的方法对目标元素光谱信号进行有效增强,信号的线性决定系数(R^(2))从0.97降至0.99,相对标准偏差(RSD)从6.47%降至1.07%,增强了信号的准确性和可用性。本文所研制的自激式ICP光源,通过射频放大和阻抗匹配一体化设计缩小了体积,变频技术使阻抗匹配速度从毫秒级提升到纳秒级,镀金工艺的MOSFET技术使最大输出功率从原来的1800 W增加到2400 W,为ICP光源的进一步优化和应用奠定了基础,具有重要的科学研究和工程实践意义。

摘要：针对由外生系统描述的扰动的抗扰控制方法一直是研究热点。本文针对一类含有非线性扰动的非线性系统,利用径向基函数模糊逻辑系统逼近系统及外生系统中的未知非线性函数,设计了一种新型的模糊干扰观测器(FDO)估计非线性扰动。构造了一种新颖的干扰估计误差观测器来逼近自适应更新律中的干扰估计误差。在此基础上,结合线性矩阵不等式(LMI)提出了一种基于FDO的自适应模糊控制方法,并利用李雅普诺夫方法分析了闭环系统的稳定性。最后,采用仿真实验验证了所设计的控制方法。实验结果表明,所提出的方法在控制精度及干扰估计精度上均优于传统的抗扰控制方法。

摘要：文章以贵州黔东南苗族聚居地布艺刺绣为研究对象,讨论苗绣工艺的形成原因和艺术形态,以及作为一种文化介质,它是如何在助力黔东南苗族族群文化中发挥作用的。作者以黔东南地区苗绣工艺的集群成因作为出发点,重点归纳梳理黔东南苗绣的材质特征、工艺形态、色彩构成、纹饰布局、文化意蕴5大艺术形态。并透过黔东南苗绣的艺术形态,解析出上述艺术形态分别是受到了地域、历史和文化等多方面因素的影响所驱使。通过研究黔东南苗绣工艺的艺术形态及其特征成因,折射出了苗绣工艺所蕴涵的艺术文化价值和民族精神。