摘要：In view of the problem that it＇s difficult to accurately grasp the influence range and transmission path of the vehicle top design requirements on the underlying design parameters. Applying directed-weighted complex network to product parameter model is an important method that can clarify the relationships between product parameters and establish the top-down design of a product. The relationships of the product parameters of each node are calculated via a simple path searching algorithm, and the main design parameters are extracted by analysis and comparison. A uniform definition of the index formula for out-in degree can be provided based on the analysis of out- in-degree width and depth and control strength of train carriage body parameters. Vehicle gauge, axle load, crosswind and other parameters with higher values of the out-degree index are the most important boundary condi- tions; the most considerable performance indices are the parameters that have higher values of the out-in-degree index including torsional stiffness, maximum testing speed, service life of the vehicle, and so on; the main design parameters contain train carriage body weight, train weight per extended metre, train height and other parameters with higher values of the in-degree index. The network not only provides theoretical guidance for exploring the relationship of design parameters, but also further enriches the appli- cation of forward design method to high-speed trains.

摘要：基于玛纳斯河流域中游平原灌区及其周边24个气象站点2013年的气象资料,采用分段单值平均法计算棉花作物系数,利用参考作物法确定灌区各站点棉花不同生育期耗水强度,结合Arc GIS空间插值,分析灌区棉花耗水强度在不同生育期和灌区空间尺度上的变化规律,并确定灌区棉花设计耗水强度。结果表明:灌区棉花全生育期耗水强度呈现先增大后减小的变化趋势,大小顺序为花铃期(5.64~6.84 mm/d)>蕾期(3.74~4.70 mm/d)>吐絮期(2.00~2.50 mm/d)>苗期(1.62~1.76 mm/d);灌区棉花全生育期平均耗水强度自西南向东北呈现递增趋势,介于3.45~3.98 mm;玛河灌区棉花设计耗水强度应在5.69~6.45 mm间选取。

摘要：目的 :针对高寒区野战条件下口腔诊疗难的问题,设计一款高寒区野战条件下单兵便携式口腔治疗装置。方法:该装置采用拉杆箱式结构,由外箱、内框架和操作面板组成,外箱采用低密度聚乙烯材料,通过一次性滚塑工艺成型;内框架上集成高原特制压缩机、独立负压压缩机、可编程逻辑控制器(programmable logic controller,PLC)集成控制系统以及便携式高原单兵呼吸同步脉冲供氧模块;操作面板上配置三用枪、高速涡轮手机、电动变速手机、水控开关、光固化机、超声洁牙手机等治疗用设备。为验证该装置的性能,在高寒区对试验阶段样机进行测试。结果:测试结果表明,试验阶段样机机动性高、功能多样、压力足,能够满足在高寒区口腔诊疗动力气源极限连续工作且运转良好的目标。结论:该装置解决了便携式口腔治疗装置在高原气压不足且不稳定、控制系统集成化低、不易携带以及医护人员缺氧问题,提高了高寒区口腔诊疗远程机动能力,提升了我军口腔移动卫勤保障能力和装备水平。

摘要：为了寻找结构新颖、抗癌活性显著的先导化合物,以桦木醇为原料,设计并合成了一系列桦木醇-28-吲哚酯衍生物,并对合成产物进行了抗增殖活性测试、靶点预测和分子对接研究。结果表明,所有衍生物对3种癌细胞的抑制作用均优于桦木醇。其中,桦木醇-28-((6-氟)吲哚-3-)乙酸酯对3种癌细胞均表现出了低微摩尔级别的抗增殖活性(IC 50<10.00μmol/L),其对A549细胞的作用最强(IC 50=7.25μmol/L),是桦木醇的4.15倍。作用机制研究表明,上述化合物可能通过抑制PI3K-Akt通路发挥抗癌作用。总之,该化合物是一种具有良好抗癌活性的先导化合物,对其进一步的结构修饰和药理研究具有重要的意义。

摘要：人工手持打磨工具打磨作业时会产生大量粉尘,目前普遍采用负压捕集装置将粉尘限制在密闭空间,并使含尘气流定向通过除尘装置加以净化,以解决粉尘散发问题。为解决某铝件打磨车间通风防护设施效果欠佳,导致作业间粉尘无序扩散问题,提出了一种适用于小型铝制件打磨作业的“U型条缝”粉尘捕集装置结构设计方案,通过有限元模拟仿真分析方法研究了该装置的粉尘防护效果。仿真结果表明:该装置左右两侧条缝宽度为2 cm,后侧条缝宽度为5 cm,排风量为3600 m^(3)/h,内部气流通道结构为不对称斜收口结构时,控制面风速较为均匀,人员呼吸带平均风速达到1.3 m/s,且内部气流通道噪声相对较小,粉尘防护效果较好。该装置“U型条缝”罩口和内部气流通道组合式结构设计可有效捕集打磨过程产生的粉尘,降低作业场所粉尘浓度,可为手工打磨场所粉尘防护提供借鉴。

摘要：In order to simultaneously measure the initiation toughness of pure mode Ⅰ and mode Ⅱ cracks in one specimen,a large-size double-cracked concave-convex plate(DCCP)specimen configuration was *** tests were implemented in the drop plate impact *** gauges were employed to measure impact loads and crack initiation *** corresponding numerical model was established by using the dynamic finite difference program AUTODYN,and the experimental-numerical method and ABAQUS code were utilized to obtain the initial fracture toughness of the *** experiments and numerical research,we concluded that the DCCP specimen is suitable for measuring the initial fracture toughness of pure mode Ⅰ and mode Ⅱ cracks at the same time;the dynamic initiation toughness increases with the increase of loading rate and the crack initiation time decreases with increasing loading rate;the initiation toughness of mode Ⅱ crack is 0.5 times that of mode Ⅰ crack when subjected to the same loading *** the pre-crack in the vicinity of the bottom of a sample,when its length increases from 20 to 100 mm,the dynamic initiation toughness of the pure mode Ⅰ crack gradually decreases,and the longer the lower crack length is,the easier the crack would initiate,but the dynamic initiation toughness of pure mode Ⅱ crack varies little.

摘要：Two series of N-pyridylpyrazolecarboxamide derivatives were designed and synthesized by introducing D-alanine acid esters and D-serine acid esters into the skelecton of chlorantraniliprole. The obtained structures were characterized by 1H NMR, 13C NMR, elemental analysis and specific optical rotation analysis. Preliminary bioas-says indicated that some compounds displayed excellent insecticidal activities against Mythimna separate and Plutella xylostella in comparison with chlorantraniliprole. In particular, IIq showed excellent insecticidal activity against Plutella xylostella with a mortality rate of 90% at 0.01 mg·L^-1. A 3D-QSAR （CoMSIA） study was per- formed in order to disclose the insecticidal structure-activity relationship and indicate the future work. The CoMS1A study demonstrated that large substitutes and electron deficient groups at the 3-position of pyrazole ring are favora- ble, the same as a small group near the ester groups of amino acid.

摘要：以传统陶瓷工艺技术的研究成果,结合长期的陶瓷艺术设计、实际制作和现行的技艺规则及生活习尚,对银沟遗址出土陶瓷标本中部分特征较强的碗类器物在时代判断、制作工艺、造型装饰、规格使用等方面的成因加以分析研究。从而得出了这部分陶瓷的烧制技术特点、装饰艺术及美学风格及它在整个中国陶瓷史上的作用和地位。

摘要：针对姿轨控系统已经失效的目标航天器姿态控制问题,提出一种空间机器人抓捕目标后姿态接管控制方法。该方法首先利用空间机器人抓捕目标航天器,并保持在固定构型形成组合航天器;其次确定参数突变后组合航天器新的惯量主轴、主惯量和控制力矩分配矩阵;然后在状态空间建立组合航天器的非线性误差姿态动力学;最后采用-α稳定度设计方法来设计服务航天器的SDRE姿态接管控制器,并通过θ-D求解方法得到SDRE控制器的次最优控制律,实现服务航天器对目标航天器的姿态接管控制。仿真结果表明,相比传统的SDRE控制器设计,基于-α稳定度设计的SDRE控制器能够使得系统闭环极点远离虚轴,θ-D求解方法可以降低计算量,因此具有更好的稳定性和实时性。

摘要：在内撑式基坑工程中,常用的打入钢楔式活络端存在整体性差、点接触受力、承载力小、刚度弱等缺陷,不利于基坑工程变形和稳定控制。为改进活络端结构,设计研发了一种螺栓紧固锥楔式(BFW)活络端。该文首先阐述其结构、功能及工作原理,计算其承载力与刚度,采用数值模拟分析其力学特征;然后,设计制作3组足尺试件,在试验室进行弹性加载试验与最不利工况下极限承载力加载试验,测试了不同调节长度及轴心与偏心荷载作用下的承载力与刚度,得到了其破坏形态;最后,将BFW活络端的力学参数与常用的不同型号钢支撑的力学参数进行对比,研究了其适用性。研究结果表明:BFW活络端结构简单,受力明确,承载力和刚度大;通过理论分析、数值模拟和室内加载试验,证明其工作原理可靠;与不同规格的钢支撑配套使用,满足"强节点、弱构件"结构设计理念。该文给出的BFW活络端的型号适用609/630型号钢支撑,若与800型号钢支撑配套使用,需要设计更强活络端。