摘要：Two kinds of semi-solid samples of AZ80−0.2Y−0.15Ca(wt.%)(AZ80M)magnesium alloy were prepared by semi-solid isothermal heat treatment of materials with and without equal channel angular pressing(ECAP)*** microstructures of initial and semi-solid treated samples were compared and *** results showed a significant difference in the liquid phase distribution between three-pass ECAP processed(3P)and as-received samples during the isothermal heating *** semi-solid 3P sample showed a more uniform liquid distribution due to its smaller dihedral ***,the coarsening processes of solid grains of as-received and 3P samples were dominated by the coalescence and Ostwald ripening mechanism,*** difference of coarsening processes was mainly related to the proportion of the high-angle grain boundaries in materials,which further affected the evolution behavior of the liquid pools.

摘要：The effects of yttrium(Y)and yttrium+calcium(Y+Ca)additions on the electrochemical properties and discharge performance of the as-extruded Mg−8Al−0.5Zn−0.2Mn(AZ80)anodes for Mg−air batteries were *** results show that the addition of 0.2 wt.%Y increased the corrosion resistance and discharge activity of AZ80 *** was attributed to the fine and sphericalβ-Mg_17)Al_(12) phases dispersing evenly in AZ80+0.2Y alloy,which suppressed the localized corrosion and severe“chunk effect”,and facilitated the rapid activation ofα-*** addition of 0.2 wt.%Y and 0.15 wt.%Ca generated grain refinement and a reduction of theβ-Mg_17)Al_(12) phase,resulting in a further enhancement in discharge ***,the incorporation of Ca in Mg_17)Al_(12) and Al_(2)Y compounds compromised the corrosion resistance and anodic efficiency of AZ80+0.2Y+0.15Ca ***,AZ80+0.2Y anode exhibited excellent overall discharge performance,with the peak discharge capacity and anodic efficiency of 1525 mA·h·g^(−1) and 67%at 80 mA/cm^(2),13%and 14%higher than those of AZ80 anode,respectively.

摘要：采用氧化焙烧+氰化浸出工艺处理陕西某含碳金矿。优化的焙烧条件为680℃焙烧2h,氧化焙砂氰化浸出的最佳条件为:氰化钠浓度1 000g/t、浸出时间24h、物料粒度-0.074mm占90%以上,在此条件下金浸出率达86.91%,活性炭吸附金效率高,浸出过程是整个过程的限制环节。

摘要：建立完整有效的大坝帷幕防渗体系,是保证水库顺利竣工、正常运行的关键。本文以青海省晓龙沟水库为例,提出一种经济可靠的重力坝帷幕灌浆加深方案。采用现场灌浆试验数据结合数值模拟计算,论证了帷幕灌浆加深方案的可行性,并在此基础上分析验证了大坝的渗漏量、渗流分布、扬压力等关键物理力学参数的合理性。该方案能够有效提高帷幕整体性和完整性,当岸坡部分坝基帷幕底界的灌前透水率稍偏大,而坝基渗流、应力满足水库大坝设计要求时,可不再对岸坡坝基帷幕进行加深。研究成果可为类似条件下大坝帷幕灌浆提供指导和参考。

摘要：A novel 22MnMoB hot stamping steel was designed. The continuous cooling transformation （CCT） measurement of the 22MnMoB steel showed that the ferrite-bainite microstructure could be obtained at cooling rates lower than 25 ℃/s, and the complete martensite structure required the cooling rate higher than 30 ℃/s. The experiments with non-uniform die temperatures were carried out to obtain tailored properties. The results showed that strength of 1 411 MPa and elon- gation of 6% could be obtained in the hard zone, and strength of 916 MPa and elongation of 9% could be obtained in the soft zone, which can be realized by controlling the die temperature at 400 ℃. The transition zone was found smooth and could be beneficial to reduce the stress concen tration and therefore improve the performance of components.

摘要：Carbohydrates, with broad-spectrum structures and biological functions, are key organic compounds in nature, along with nucleic acids and proteins. As part of our ongoing efforts to develop a new class of pesticides with novel mechanism of action, a series of novel N-glycosyl-l-pyridyl-lH-pyrazole-5-carboxamide was designed and synthesized via the reactions of glycosyl methanamides and pyridyl-pyrazole acid. The compounds were characte- rized by IH NMR and 13C NMR. The bioassay results indicate that some of these compounds exhibit moderate insec- ticidal activities and assessed as potential inhibitors of calcium channels. The modulation of voltage-gated calcium channels by compounds 4a and 5a in the central neurons isolated from the third instar larvae of Spodoptera exigua was studied by whole-cell patch-clamp technique. In addition, compound 5a inhibits the recorded calcium currents reversible on washout. Experimental results also indicate that compound 5a did not release stored calcium from the Endoplasmic Reticulum. The present work demonstrates that N-glycosyl-l-pyridyl-lH-pyrazole-5-carboxamides cannot be used as possible inhibitors of calcium channels for developing novel pesticides.

摘要：For about three decades, DNA-based nanotechnology has been undergoing development as an assembly method for nanostructured materials. The DNA origami method pioneered by Rothemund paved the way for the formation of 3D structures using DNA self assembly. The origami approach uses a long scaffold strand as the input for the self assembly of a few hundred staple strands into desired shapes. Herein, we present a 3D origami "roller" (75 nm in length) designed using caDNAno software. This has the potential to be used as a template to assemble nanoparticles into different pre-defined shapes. The "roller" was characterized with agarose gel electrophoresis, atomic force microscopy (AFM) and transmission electron microscopy (TEM).

摘要：A series of strobilurin-l,2,4-triazole derivatives containing a furan or thiophen ring was designed andsynthesized. The structures of the compounds were characterized by 1H NMR, 13C NMR and HRMS spectra. Thebioassays indicated that the fungicidal activities of compounds 10b（EC50=14.82 mg/L） and 10c（EC50=18.72 mg/L）against Cercospora arachidicola Hori in vitro were much higher than that of Azoxystrobin as control（EC50=40.54mg/L） and the fungicidal activities of compounds 10u（EC50=8.66 rag/L） and 10n（EC50=9.89 rag/L） against Rhizotoniacerealis in vitro were higher than that of the same control（EC50=10.86 rag/L）. Compounds 10b, 10c, 1011 and 10kcould be considered as the leading compounds for further investigation.

摘要：人群筛查可以降低大肠癌的死亡率,是控制大肠癌疾病负担的有效措施。人群筛查策略的制定和实施是区域性癌症控制规划的重要内容。上海于2011年将"社区居民大肠癌筛查"列入重大公共卫生服务项目,接着,原市卫生局等机构联合下发了《关于组织开展本市重大公共卫生服务项目"上海市社区居民大肠癌筛查"的通知》,在全市范围向符合条件的居民免费提供大肠癌筛查服务。通过科学论证和反复实践,上海在全国率先将一项成熟的癌症筛查措施纳入公共卫生服务,是我国大规模人群癌症筛查在公共卫生政策上一大突破。本文回顾了该项目从设计、社区试点到形成公共卫生政策而在全市推广的历程,讨论了大肠癌筛查从技术措施转化为公共卫生服务项目,并在人群中推广实施过程中,如何应用循证的方法解决相关技术性和实施性问题。

摘要：随着工业的发展,染料废水对人类和环境的危害愈加显著,其中偶氮类的亚甲基蓝这种染料废水不仅色度大,而且难以降解.因此设计一种高效且灵敏的吸附剂来去除亚甲基蓝对人类和环境的危害是亟须解决的问题.本研究利用基于色散力校正的密度泛函理论(DFT-D)的第一性原理方法探索了本征及掺杂磷烯吸附剂对亚甲基蓝的吸附机理,并详细考察了本征及掺杂Al,Ca,Ti和Fe金属原子后的磷烯对亚甲基蓝吸附的影响.研究结果表明亚甲基蓝初始构型会影响磷烯对其吸附,当亚甲基蓝平躺于磷烯表面时有较大的吸附,且金属原子掺杂显著地影响其对亚甲基蓝的吸附能力,掺杂金属原子均增大了磷烯对亚甲基蓝的吸附.其中吸附能力是Fe掺杂磷烯>Ca掺杂磷烯>Ti掺杂磷烯>Al掺杂磷烯.研究结论对于亚甲基蓝的处理带来了新的指导方向,有望为相关染料废水的检测和去除提供有意义的理论参考.