摘要：A series of new benzimidazole derivatives were designed and *** chemical structures were testified by 1 H NMR,infrared spectroscopy(IR),mass spectrography(MS),and elemental *** potent antiviral properties indicated the prospect of new *** 13,16,18,19,21,22,and 23 were identified as novel antivirus with much better selective activity and inhibitory activity than the comparable ribavirin against Coxsackie virus B_(3) in VERO cells.