摘要：An efficient chlorination roasting process for recovering zinc(Zn)and lead(Pb)from copper smelting slag was *** models were established,illustrating that Zn and Pb in copper smelting slag can be efficiently recycled during the chlorination roasting *** decreasing the partial pressure of the gaseous products,chlorination was *** Box−Behnken design was applied to assessing the interactive effects of the process variables and optimizing the chlorination roasting ***_(2) dosage and roasting temperature and time were used as variables,and metal recovery efficiencies were used as *** the roasting temperature was 1172℃ with a CaCl_(2) addition amount of 30 wt.%and a roasting time of 100 min,the predicted optimal recovery efficiencies of Zn and Pb were 87.85%and 99.26%,respectively,and the results were validated by experiments under the same *** residual Zn-and Pb-containing phases in the roasting slags were ZnFe_(2)O_(4),Zn_(2)SiO_(4),and PbS.

摘要：以国产杉木锯材和毛竹展平竹为基材,在施胶量200 g/m^(2),压力0.6 MPa的工艺参数下制备了一种正交胶合竹木(CLBT)。通过三点弯曲试验研究了CLBT在强轴和弱轴两个方向上的抗弯性能,并根据剪切类比理论计算了CLBT在强轴和弱轴方向上的弯曲强度标准值和设计值。结果表明:CLBT在强轴和弱轴方向上的弯曲强度分别为58.19、25.25 MPa,弯曲弹性模量分别为8.54、2.56 GPa,从整体上看,CLBT具有较好的抗弯性能。抗弯试验中CLBT在两个方向上表现出不同的破坏模式,强轴方向主要表现为杉木层滚动剪切以及杉木层与展平竹界面层间剪切破坏,而弱轴方向上主要表现为最底层展平竹层沿轴向受拉断裂以及垂直层的杉木受拉破坏。通过剪切类比理论计算得到,CLBT在强轴方向的弯曲强度标准值和设计值分别为44.17 MPa和21.03 MPa,弱轴方向上其弯曲强度标准值和设计值分别为6.85 MPa和3.26 MPa,达到了ANSI/APA PRG 320-2019中E1等级对抗弯性能的要求。

摘要：Hydrogels are a class of special materials that contain a large amount of water and behave like *** materials have found broad applications in tissue engineering,cell culturing,regenerative medicine ***,the exploration of peptide-based supramolecular hydrogels has greatly expanded the repertoire of hydrogels suitable for biomedical ***,the mechanical properties of peptide-based hydrogels are intrinsically ***,it is crucial to develop methods that can improve the mechanical stability of such peptide-based *** this review,we explore the factors that determine or influence the mechanical stability of peptide-based hydrogels and summarize several key elements that may guide scientists to achieve mechanically improved *** addition,we exemplified several methods that have been successfully developed to prepare hydrogels with enhanced mechanical *** mechanically strong peptide-based hydrogels may find broad applications as novel *** is still challenging to engineer hydrogels in order to mimic the mechanical properties of biological *** hydrogel materials with optimal mechanical properties suitable for various types of biological applications will be available in the near future.

摘要：Anisotanols A—D(1-4),four new compounds possessing an unprecedented sesquiterpenoid skeleton with a congested tricyclic 6/3/5 ring system,were obtained from Anisodus *** structures were elucidated by comprehensive spectroscopic techniques,and the absolute configurations were confirmed via ECD calculations and single-crystal X-ray diffractions.A putative biosynthetic pathway for these compounds was *** evaluation disclosed that compound 3 showed anti-angiogenic activity by inhibiting the viability,migration,and tube formation in HUVECs.

摘要：An essential step for cancer vaccination is to break the immunosuppression and elicit a tumor-specific immunity.A major hurdle against cancer therapeutic vaccination is the insufficient immune stimulation of the cancer vaccines and lack of a safe and efficient adjuvant for human *** discovered a novel cancer immunostimulant,trichosanthin(TCS),that is a clinically used protein drug in China,and developed a well-adaptable protein-engineering method for making recombinant protein vaccines by fusion of an antigenic peptide,TCS,and a cell-penetrating peptide(CPP),termed an"allin-one"vaccine,for transcutaneous cancer *** TCS adjuvant effect on antigen presentation was investigated and the antitumor immunity of the vaccines was investigated using the different tumor *** vaccines were prepared via a facile recombinant *** vaccines induced the maturation of DCs that subsequently primed CD8^(+)T *** TCS-based immunostimulation was associated with the STING *** general applicability of this genetic engineering strategy was demonstrated with various tumor antigens(i.e.,legumain and TRP2 antigenic peptides)and tumor models(i.e.,colon tumor and melanoma).These findings represent a useful protocol for developing cancer vaccines at low cost and time-saving,and demonstrates the adjuvant application of TCSdan old drug for a new application.

摘要：文章针对现代建筑施工行业中安全事故频发、监管效率低下等问题,分析了当前施工安全监控的困境,明确了将人工智能与边缘计算引入施工安全监控的必要性,设计了基于人工智能与边缘计算技术的施工安全监控的整体应用架构,提出了应用于工地场景的人工智能模型技术部署方案以及工地安全细分场景的智能应用技术布局。在智慧工地的建设中,智能安全监控系统不仅可有效防止安全隐患,还能实现无人值守,从而优化管理成本。该系统旨在通过人工智能与边缘计算技术实时数据分析与智能预警,实现对施工现场的全面、高效、精准管理,从而提升施工安全管理水平。

摘要：为提升飞行器气动外形优化设计效果,研究了新型飞行器在大空域、宽速域范围的气动适应性问题,提出一种基于气动-弹道一体化模型的外形优化设计方法。通过考虑气动和弹道的耦合作用,综合利用类型函数/形状函数转换技术、气动工程估算方法和Radau伪谱法,建立飞行器气动-弹道一体化模型。基于该模型,通过明确优化目标和约束条件,给出基于Kriging的气动外形优化方法,实现在多参数约束条件下的飞行器气动外形高效全局优化。以升力体构型飞行器为例,开展气动外形优化设计,结果表明该方法能较好地描述大空域、宽速域的气动和弹道特征,有效提升飞行器气动外形设计精度和水平,可为新型飞行器总体设计提供技术支撑。

摘要：系统性地采取严格控制光学元件加工装配精度、采用大质量高稳定性光机结构、运用精密热控等方法,是以往保证空间相机光学系统高性能成像质量的常规方法,但同时该策略的实施也给相机研制带来了较高的经济与资源代价。面对高性能空间光学相机低成本化的发展趋势,降低光学系统误差敏感度,在保证成像性能的同时降低实现成本,是需要面对与解决的课题。以某小型空间相机研制为背景,应用光学系统低误差敏感度设计方法(降敏设计方法),对相机焦距500 mm、相对孔径1∶5、视场角2ω=4°的同轴两镜折反射式光学系统进行了降敏设计。结果表明,基于降敏设计方法获得的光学系统不仅像差校正理论结果表现优异,调制传递函数接近衍射极限,同时,仿真显示其在误差干扰下光学系统鲁棒性好,为相机的快速低成本制造提供了保证。光学系统降敏设计方法对高性能小型空间载荷的设计与低成本快速研制具有重要的应用价值。

摘要：基于9层支撑抗弯钢框架和支撑铰接钢框架,分别采用与屈曲约束支撑(BRB)的等强原则和等核心板面积原则设计自定心屈曲约束支撑(SC-BRB)框架,并对建立的6个支撑框架模型进行10条地震波下的非线性时程分析,结果表明:与BRB框架相比,SC-BRB能有效控制结构的残余变形;因为支撑铰接钢框架由地震引起的主体结构损伤较支撑抗弯钢框架小,所以结构的自定心效果也更好;基于等强原则的SC-BRB框架由于支撑刚度较小,因此其结构层加速度和支撑轴力小于按等核心板面积原则设计的SC-BRB框架;基于等核心板面积原则的SC-BRB框架凭借支撑较强的耗能能力,其层间位移角的控制要优于按等强原则设计的SC-BRB框架,且其较大的预张力和预拉杆截面面积也更利于提高结构的自定心效果和限制薄弱层的出现。

摘要：蒸汽发生器(SG)是压水堆核动力装置中重量及尺寸较大的关键设备之一,且随着SG大容量、大型化的发展趋势使其重量和体积进一步增加,这给设备的运输和布置带来了困难,因此,有必要在SG设计中,在满足换热性能及安全要求的条件下,寻找设计参数的最佳组合,以减小SG重量或体积。本文建立了SG重量评价程序,并在对影响SG重量的热工参数和结构参数进行敏感性分析的基础上,采用复合形-遗传优化算法,以SG重量为目标进行了参数优化设计。优化结果显示:与原始方案相比,优化设计方案的重量减小了17.16%,优化效果显著,并从理论上证明了优化的可能性,研究结果可为实际工程设计提供参考。