摘要：Au sites supported on Ti-containing materials(Au/Ti-containing catalyst)are currently considered as a promising catalyst for the propylene epoxidation owing to the synergistic effect that hydrogen peroxide species formed on Au sites diffuses to the Ti sites to form the Ti-hydroperoxo intermedi-ates and contributes to the formation of propylene oxide(PO).In principle,thermal treatment will significantly affect the chemical and physical structures of Ti-containing ***,the synergy between tailored Ti sites with different surface properties and Au sites is highly expected to enhance the catalytic performance for the ***,we systematically studied the intrinsic effects of different microenvironments around Ti sites on the PO adsorption/desorption and conversion,and then effectively improved the catalytic performance by tailoring the number of surface hydroxyl *** Ti^(Ⅵ) material with fewer hydroxyls stimulates a remarkable enhancement in PO selectivity and H_(2) efficiency compared to the Ti^(Ⅵ) material that possessed more hydroxyls,offering a 7-fold and 4-fold increase,*** expected,the Ti^(Ⅵ+Ⅳ) and Ti^(Ⅳ) materials also exhibit a similar phenomenon to the Ti^(Ⅵ) materials through the same thermal treatment,which strongly supports that the Ti sites microenvironment is an important factor in suppressing PO con-version and enhancing catalytic *** insights could provide guidance for the rational preparation and optimization of Ti-containing materials synergizing with Au catalysts for propylene epoxidation.

摘要：针对概念设计中多意象设计方案决策困难的现象,提出了一种产品形态多意象蛛网灰靶决策方法。首先,运用感性工学相关方法获取设计主体的认知数据,结合熵权法及博弈论思想构建基于设计主体认知数据的综合评价模型,并根据各意象的设计主体综合评价数据确定各意象的权重关系;其次,通过人工选择的方式从产品形态进化系统中选择多个进化方案,运用蛛网图表征各进化方案的意象关系,构建多意象蛛网灰靶决策模型,计算决策系数,对其进行比较排序,得到符合设计主体认知的相对最优方案;最后,应用灰色关联分析法验证该决策模型的可行性。结果表明,该模型能够帮助设计师在设计决策阶段快速、准确地确定符合多设计主体认知的多意象方案,为产品方案的多意象决策提供了新的理论和方法。

摘要：讨论了角色控制模型的基本概念和原理,研究并提出了基于角色存取控制RBAC模型的网络数据库安全系统设计方案,最后给出了网络数据库安全系统实现。

摘要：A numerical solution of the weight function for a two-electrode electromagnetic flowmeter was proposed. The solution was obtained by using the finite element method based on the basic equation of a traditional two-electrode electromagnetic flowmeter. The two-dimensional distribution of the weight function of the electromagnetic flowmeter obtained was verified by the analytical solution. Three-dimensional distribution of the weight function was also presented in the paper. It can be employed to analyze the sensitivity and linearity of the electromagnetic flowmeter with non-uniform magnetic field, and even to assist the design of the excitation coil pair.

摘要：针对多相材料结构的拓扑优化出现的棋盘格问题,研究了周长约束控制方法。根据多相材料组分情况下结构有限单元密度变量的定义特点,拓展了周长约束的原始定义概念并提出了相应的4种周长控制约束新格式。以结构最大刚度优化设计问题为例,结合凸规划对偶求解方法验证了4种格式的有效性。计算结果表明:独立控制各类变量周长的方式能更有效地实现多相材料结构的拓扑优化设计,获得消除棋盘格和中间变量值的清晰结果。

摘要：为建立可同时检测牛腺病毒3型(BAdV-3)、牛呼吸道合胞体病毒(BRSV)、牛支原体(MB)、牛传染性鼻气管炎病毒(IBRV)和牛病毒性腹泻病毒(BVDV)的五重PCR方法,基于病原体的保守序列设计5对特异性引物。对退火温度和引物浓度筛选,验证方法的特异性、敏感性和重复性,建立可同时检测BAdV-3、BRSV、MB、IBRV和BVDV的五重PCR方法,并初步应用于临床。结果表明,该方法特异性强,仅对BAdV-3、BRSV、MB、IBRV和BVDV有特异性扩增,最适退火温度54.5℃,最适引物浓度0.6μmol/L;对5种病原体最低检出限分别为BAdV-31.67×10^(4)拷贝/μL、BRSV 1.58×10^(4)拷贝/μL、MB 1.75×10^(3)拷贝/μL、IBRV 1.44×10^(3)拷贝/μL、BVDV 1.25×10^(4)拷贝/μL。用该五重PCR和单项PCR分别检测268份临床样本,显示五重PCR阳性检出率分别为BAdV-39.33%(25/268)、BRSV 7.09%(19/268)、MB 28.73%(77/268)、IBRV 11.94%(32/268)、BVDV 25.75%(69/268)。混合感染主要以MB和BVDV为主,感染率为12.69%(34/268)。五重PCR扩增结果与单项PCR扩增结果符合率为93.36%,表明建立的五重PCR方法为临床快速检测及流行病学调查提供了技术支持。

摘要：目的以可持续设计的有关理论作为指导,以木马设计集团的新能源充电桩产品设计为样例,降低产品使用过程中的人为损耗,为共享汽车的充电问题提出智慧化解决方案。方法首先,以“DfS”(Design for Sustainability)方法为指导,通过用户访谈构建动态用户画像,挖掘传统充电桩各阶段存在的痛点,并从可持续设计的视角建立新能源充电产品服务系统的理论框架;其次,通过定性及定量的方法挖掘用户显性与隐性需求,总结新能源充电系统的设计策略;最后,利用该策略指导设计新能源充电系统,并利用可持续性晴雨表进行设计验证。结果提出可持续设计视角下新能源充电系统的设计原则;基于用户需求设计出自动化新能源充电系统,解决传统手动充电带来的过程繁琐的问题。结论新能源充电系统设计策略的构建能够推动自动化、智能化、网联化和共享化深度融合,实现城市交通体系智慧化发展。

摘要：A series of novel indole derivatives were designed and synthesized and their inhibitory activity against B-Raf and HepG2 cell were also described. Among them, compounds 7a and 7b exhibited excellent potency, which showed the potential for further research as lead compounds.

摘要：以(3aS,6aR)-1,3-二苄基四氢-1H-噻吩并[3,4-d]咪唑-2,4-二酮(4)为原料,与1,4-二氯丁烷及CO_(2)发生双格氏化反应得到合成生物素的关键中间体(E)-5-(3aS,6aR)-1,3-二苄基-2-氧代六氢-4H-噻吩并[3,4-d]咪唑-4-亚基戊酸(3),收率为93%。通过实验确证该步反应的主要杂质为化合物5-(1-环戊烯基)戊酸(3a),并设计了该化合物的合成工艺,以1,4-二氯丁烷为原料,投料比n(1,4-二氯丁烷)∶n(镁粉)为1∶2.2,通入CO_(2)的反应温度为-30℃,保温搅拌4 h;再往上述反应液中加入10%稀硫酸中和至pH=4,经60℃保温搅拌4 h,可得68%收率的化合物(3a)。该研究一方面确证了烯酸(3)合成过程中的杂质(3a),另一方面设计了化合物(3a)的合成工艺,为进一步开发利用该化合物(3a)提供了参考。

摘要：为降低大型陶瓷成形设备开发成本,缩短开发周期,提高工作效率和操作舒适性,应用JACK软件对陶瓷滚压成形机进行人机工程仿真,并对其进行了改进设计。通过对陶瓷滚压成形机技术特征与工作原理的分析,确定了操作过程仿真的动态姿势节点,在此基础上,提出滚压成形机人机适配性的关键因素,并按照搬运工件的工作类型进行操作台高度仿真;按照达到包络的要求进行操作开关位置布局,提出尺寸设计建议,并对改进后的设计方案进行人机工程评价。结果表明:改进后的设计方案有助于减少工人肌肉骨骼疾病,可提高生产效率。