摘要：A novel method was proposed to design the structure of a bone tissue engineering scafold based on triply periodic minimal *** this method,reverse engineering software was used to reconstruct the surface from point cloud *** method overcomes the limitations of commercially available software packages that prevent them from generating models with complex surfaces used for bone tissue engineering ***,the fluid feld of the scafolds was simulated through a numerical method based on fnite volume and the cell proliferation performance was evaluated via an in vitro *** cell proliferation and the mass flow evaluated in a bioreactor further verifed the flow feld simulated using computational fluid *** result of this study illustrates that the pressure value drops rapidly from 0.103 Pa to 0.011 Pa in the y-axis direction and the mass flow is unevenly distributed in the *** mass flow in the side outlets is observed to be approximately 24.3 times higher thanthe ***,although the mean value of wall shear stress is signifcantly more than 0.05 Pa,there is stil a large area with a suitable shear stress below 0.05 Pa where most cells can proliferate *** result shows that th inlet velocity 0.0075 m/s is suitable for cell proliferation in the *** study provides an insight into the design analysis,and in vitro experiment of a bone tissue engineering scafold.