摘要：An analysis has been completed for a comprehensive set of vertical,dilute-phase pneumatic conveying pressure drop data from an investigation by *** data were collected in the established flow region for eight different materials conveyed in 0.05-,0.10-,0.20-m internal diameter,20-m tall steel *** velocities derived from the pressure drop data were used to develop an equation of motion that includes terms for pipe diameter,terminal velocity,coefficient of restitution,and particle *** best data fit was achieved using the actual gas density and the actual gas velocity adjusted for *** the terminal velocity for voidage,an approach recommended by many investigators,did not improve the fit for reasons identified by the present *** the equation of motion,particle velocities were predicted and used to calculate total pressure drops that are within±15%of the measured *** calculated values also produce the characteristic trough-shaped total pressure drop curves allowing the minimum pressure drop gas velocity to be determined without recourse to a separate correlation.A comparison with other studies using shorter risers indicates that data from these studies likely include acceleration effects.A separate study will investigate this observation further.

摘要：This paper is concerned with the free vibration analysis of open circular cylindrical shells with either the two straight edges or the two curved edges simply supported and the remaining two edges supported by arbitrary classical boundary conditions. Based on the Donnell-Mushtari-Vlasov thin shell theory, an analytical solution of the traveling wave form along the simply supported edges and the modal wave form along the remaining two edges is obtained. With such a unidirectional traveling wave form solution, the method of the reverberation-ray matrix is introduced to derive the equation of natural frequencies of the shell with different classical boundary conditions. The exact solutions for natural frequencies of the open circular cylindrical shell are obtained with the employment of a golden section search algorithm. The calculation results are compared with those obtained by the finite element method and the methods in the available literature. The influence of length, thickness, radius, included angle, and the boundary conditions of the open circular cylindrical shell on the natural frequencies is investigated. The exact calculation results can be used as benchmark values for researchers to check their numerical methods and for engineers to design structures with thin shell components.

摘要：Bromination is used as a strategy to improve biological activity in medicinal *** order to study on the structure-activity relationships of the novel acetylcholinesterase inhibitors with 7H-thiazolo[3,2-b]-1,2,4-triazin-7-one scaffold,based on our previous work and molecular modeling,a series of novel 3-aryl-6-（bromoarylrnethyl）-7H-thiazolo[3,2-b]-1,2,4-triazin-7-one derivatives were designed by molecular docking,synthesized and characterized by mass spectra,infrared spectra,proton NMR and elemental *** study of AChE inhibitory activity was carried out using the Ellman colorimetric assay with huperzine-A as the positive *** of all target compounds exhibited more than 45%inhibition at 10μmol/*** preliminary structureactivity relationship was the bromine atoms and the hydroxyl group at the phenyl ring at the C6 position of the parent nucleus played significant roles in the AChE inhibitory activity of the target compounds.

摘要：A series of novel naphthalimide-derived metronidazoles as new type of antimicrobial agents were for the first time designed, synthesized and characterized by NMR, IR and HRMS spectra. Experimental results revealed that most of them displayed moderate to good antibacterial activity towards Gram-positive and negative bacteria. Especially, compound 7b was able to not only exhibit effective inhibition towards the growth of P. vulgaris（MIC = 0.002 mmol/m L） and S. dysenteriae（MIC = 0.01 mmol/m L）, but also have rapidly killing effect and prevent the development of bacterial resistance. Further research revealed that the highly active molecule 7b could not only intercalate into calf thymus DNA to form a steady supramolecular complex and thus might block DNA replication to exert the powerful bioactivities, but also be effectively transported by human serum albumin（HSA） via the formation of the 1：1supramolecular complex, in which hydrogen bonds and hydrophobic effect played important roles in the association of compound 7b with HSA. Molecular docking indicated that the supramolecular interactions between 7b and topoisomerase II were driven by hydrogen bonds.

摘要：A campus bus network design and evaluation, taking Tsinghua University as an example, is investigated in this paper. To minimize the total cost for both passengers and operator, the campus bus system planning in a sequential approach is discussed, including the route network design, headway （i.e., the inverse of service frequency） optimization, and system evaluation. The improved genetic algorithm is proposed to optimize the route network based on the route property, and the impacts of the fluctuation of passenger demand and average traveling time are analyzed. The identity proportion in the headway optimization is then introduced with full consideration of its impacts. Based on the actual variety of passenger demand, a non-fixed schedule demonstrates its efficiency. VISSIM is finally adopted to simulate the campus bus system and a comprehensive evaluation system for the campus bus is developed. Compared with the current bus network and the one without considering the route property, the evaluation of the proposed approach shows an improvement of 18.7% and 10.1%, respectively. Moreover, the sequential approach shows an efficiency significance for the development of public transit systems passengers and operator. mprovement over the alternative method. It is of great n large industrial parks to decrease the total cost for both

摘要：由于特殊的分子结构,两亲功能分子具有易加工、低成本和高性能等优势,因而广泛应用于功能薄膜材料制备和细胞膜相关的仿生学研究中。于是课题基于侧链工程,设计并合成了一类功能两亲分子Cn PA-BTBT (n=3–11),分子使用不同长度烷基链连接疏水的半导体骨架和亲水的极性功能基团。使用基于示差扫描量热法的热力学研究分析不同长度烷基链的体积效应、奇偶性、柔性和其它烷基链特性对材料整体性能影响,并最终根据热力学测试结果,提出了一个三态分子模型。此工作为功能有机半导体材料设计、合成、优化以及目标性能材料的筛选提供了实验依据。

摘要：Flexible supercapacitors(SCs)have become a popular research topic due to their extra-long service life,foldability,and ***,their low energy density restricts their ***,we synthesized phosphorus-doped bimetallic sulfides embedded in heteroatom-doped(N,S,and P)carbon shells(P-ZCS/HC)using a simple approach to create high-performance flexible *** three-dimensional architecture made by interlaced nanosheets was preserved,and raised nanoparticles appeared on the rough surface during the annealing operation,increasing the specific surface area and potential exposure to the *** is noteworthy that the optimal P-ZCS/HC electrode possessed a remarkable capacity of 1080 C g^(-1)at 1 A g^(-1)along with superb cycling *** extraordinary properties were primarily caused by plentiful redox reactions,enhanced conductivity,and synergic effects of the P-doped metal sulfides and heteroatom-doped carbon *** functional theory simulations confirmed the good function of the P-doped electrodes and their ability to boost conductivity,improve reactive dynamics,and promote ***,the assembled all-solid-state hybrid SC exhibited a maximum energy density of 62.9 W h kg^(-1)and a power density of 16 k W kg^(-1),while being able to maintain 92.0%of its initial capacity after 10,000 *** systematic report provides new insight into the design and synthesis of electrodes with complex components and outstanding structures for the flexible energy field.

摘要：在微弱信号检测中,锁相放大器具备较强的检测能力。为了能在其测量系统中集成锁相放大器,本文设计了一种基于FPGA的数字锁相放大器。使用模数转换器设计采集模拟待测信号的前置电路;基于DDS原理产生两路(10~10)kHz的正余弦参考信号;采用CIC与FIR级联设计低通滤波器;基于Qt实现上位机与FPGA的串口通信。结果表明:该锁相放大器具有小型化、抗噪声能力强、可实时处理等优点,可在测量系统中集成并测量微弱信号。

摘要：针对麻雀搜索算法(SSA)容易陷入局部最优、求解精度不高和收敛速度较慢的问题,本文提出一种非线性正态差分SSA(NLN-DSSA)。采用改进Circle混沌映射初始化麻雀种群,提升种群多样性,提高算法在迭代开始时的全局搜索能力;引入非线性正态分布系数来控制发现者的搜索步长和收敛速度,平衡全局搜索和局部开发能力;引进差分变异策略增加种群的多样性,帮助算法跳出局部最优。在5个基准测试函数上寻优实验,结果表明:NLN-DSSA具有更好的收敛速度和寻优精度。最后将NLN-DSSA应用到无人机路径规划上,证明改进算法的有效性和实用性。

摘要：在ANSYS Workbench的基础上结合OptiSLang优化设计软件,对混流泵启动过程进行优化.利用准稳态理论和全流域模型计算数据,建立了混流泵准稳态启动过程的水力性能响应面替代模型.通过NSGA遗传算法优化内部流动状态,降低启动过程中的涡致能量损失,从而提升混流泵的水力性能.将原始混流泵与优化后混流泵的外特性、叶片压力分布进行对比,并分析混流泵内部涡结构,验证了所提出的准稳态启动过程水力性能优化方案的可行性.研究结果表明:叶片进口安放角α1,α4,α5,叶片出口安放角β1,β2,β3,β4,β5,叶片包角φ和叶片厚度系数θ对混流泵加权平均扬程和加权平均效率的影响程度较大;对比不同启动时刻下混流泵的叶片压力分布,发现该方法能够有效提升混流泵启动中后期的瞬态扬程和启动中期的水力效率.