摘要：Objective: Recen.ly, reports have in.icated that the imbalan.e of circulatin. an.iogen.c factors is importan. in.the on.et of preeclampsia. In.this study we in.estigated an.iogen.c factor levels in.women.with preeclampsia, preeclampsia superimposed on.chron.c glomerulon.phritis, gestation.l protein.ria, an. n.rmal pregn.n.ies. Study design. We measured several circulatin. an.iogen.c factors, placen.al growth factor, vascular en.othelial growth factor, soluble fms-like tyrosin. kin.se-1, an. soluble fetal liver kin.se 1. Results: Compared with women.with n.rmal pregn.n.ies, placen.al growth factor con.en.ration. were lower, an. soluble fms-like tyrosin. kin.se 1 con.en.ration. were higher in.women.with preeclampsia an. gestation.l protein.ria; soluble fms-like tyrosin. kin.se 1 con.en.ration. were also higher in.women.with preeclampsia superimposed on.chron.c glomerulon.phritis. Con.lusion. There were obvious differen.es in.the levels of circulatin. an.iogen.c factors placen.al growth factor an. soluble fms-like tyrosin. kin.se 1 amon. preeclampsia, gestation.l protein.ria, an. con.rols. The imbalan.e of an.iogen.c factors is importan. in.the on.et of preeclampsia superimposed on.chron.c glomerulon.phritis.