摘要：前不久,国际性创意工作室ID Real的新总部在西班牙马德里开业了。业主策略性地在市中心知名的萨拉曼卡区选择了一处旧仓库作为办公室的新址。该区有着规模庞大的住宅区、商务办公大楼、外交代表机构和豪华精品店,交通通达,商机无限。本案由设计公司Dariel Studio与ID Real的总经理Anouk de Lesparda以及独立设计师一起合作完成。此次的设计目标是要把这个仓库改建为一个新型的办公场所,同时加固紧邻的历史建筑,

摘要：收藏超过42万件艺术珍品的卢浮宫博物馆里有一件新旧交替、色彩夺目的沙发椅,这只古董沙发椅是典型法国巴洛克的宫廷风格,但是却与现居上海的华人设计师安东尼朝（ANTHONYCHAO）之间有着深厚的渊源.这件沙发椅上精美的立体丝绒正是出自他手,而且完全是手工织造的结果.

摘要：一、我们谈的是什么样的"回归"?美国电影中所说的非线性叙事的回归通常会上溯到昆汀·塔伦蒂诺1995年上映的电影《低俗小说》。(1)该片由三个在相对短时间跨度内发生的故事组成,三个故事内部又细分为不同的部分和情境,以"噱头"(set pieces)的方式存在(在You Tube这个视频网站上,昆汀的粉丝常常亲切称之为"噱头")。

摘要：尽管“名不正言不顺”,但是我们拒绝为“剧场性”(theatricality)下定义,因为“剧场性”的辽阔疆域不为任何单一的定义、时代或实践所限。对“剧场性”进行阐释会伴随哪些问题?一方面,必须探究“剧场性”这一当代观念如何与之前的概念一脉相承。另一方面,既要探究“剧场”(theatre)一词的本义及其隐喻的涵义,也要分析最近两个世纪的观念和实践如何影响我们对“剧场性”的理解。我们反对在今天的批评话语中,不尊重历史和事实随意使用“剧场性”这一概念,同时也希冀以相互联系、系统的阐释代替对“剧场性”东拼西凑的解释。

摘要：With the aim of reducing the cost of developing internal combustion engines,while at the same time investigating different geometries,layouts and fuels,3D-CFD-CHT simulations represent an indispensable part for the development of new *** tools are increasingly used by manufacturers,as a screening process before building the first *** paper presents an innovative methodology for virtual engine *** 3D-CFD tool QuickSim,developed at FKFS,allows both a significant reduction in computation time and an extension of the simulated domain for complete engine *** is possible thanks to a combination of coarse meshes and self-developed internal combustion engine models,which simultaneously ensure high *** present work demonstrates the capabilities of this innovative methodology for the design and optimization of different engines and fuels with the goal of achieving the highest possible combustion efficiencies and pollutant *** analysis focuses on the influence of different fuels such as hydrogen,methanol,synthetic gasolines and methane on different engine geometries,in combination with suitable injection and ignition systems,including passive and active *** operations as well as knock reduction are discussed,particularly for methane and hydrogen ***,it is shown how depending on the chosen fuel,an appropriate ad-hoc engine layout can be designed to increase the indicated efficiency of the respective engines.

摘要：Malaria still threatens global health seriously *** the current discoveries of antimalarials are almost totally focused on single mode-of-action inhibitors,multi-targeting inhibitors are highly desired to overcome the increasingly serious drug ***,we performed a structure-based drug design on mitochondrial respiratory chain of Plasmodium falciparum and identified an extremely potent molecule,RYL-581,which binds to multiple protein binding sites of *** simultaneously(allosteric site of type Ⅱ NADH dehydrogenase,Q_(o) and Q_(i) sites of cytochrome bc_(1)).Antimalarials with such multiple targeting mechanism of action have never been reported ***-581 kills various drug-resistant strains in vitro and shows good solubility as well as in vivo *** structurebased strategy for designing RYL-581 from starting compound may be helpful for other medicinal chemistry projects in the future,especially for drug discovery on membrane-associated targets.

摘要：The fields of regenerative medicine and tissue engineering offer new therapeutic options to restore,maintain or improve tissue function following disease or *** maximize the biological function of a tissue-engineered clinical product,specific conditions must be maintained within a bioreactor to allow the maturation of the product in preparation for ***,the bioreactor should be designed to mimic the mechanical,electrochemical and biochemical environment that the product will be exposed to in ***-time monitoring of the functional capacity of tissue-engineered products during manufacturing is a critical component of the quality management *** present review provides a brief overview of bioreactor engineering *** addition,strategies for bioreactor automation,in-line product monitoring and quality assurance are discussed.

摘要：Random numbers generated by pseudo-random and true random number generators (TRNG) are used in a wide variety of important applications. A TRNG relies on a non-deterministic source to sample random numbers. In this paper, we improve the post-processing stage of TRNGs using a heuristic evolutionary algorithm. Our post-processing algorithm decomposes the problem of improving the quality of random numbers into two phases: (i) Exact Histogram Equalization: it modifies the random numbers distribution with a specified output distribution;(ii) Stationarity Enforcement: using genetic algorithms, the output of (ii) is permuted until the random numbers meet wide-sense stationarity. We ensure that the quality of the numbers generated from the genetic algorithm is within a specified level of error defined by the user. We parallelize the genetic algorithm for improved performance. The post-processing is based on the power spectral density of the generated numbers used as a metric. We propose guideline parameters for the evolutionary algorithm to ensure fast convergence, within the first 100 generations, with a standard deviation over the specified quality level of less than 0.45. We also include a TestU01 evaluation over the random numbers generated.

摘要：本次项目的设计理念是将时尚元素带进商务酒店，改变商务酒店一成不变的固定模式。设计师的灵感源于法国知名西装品牌——DoRMEulL（多美）．将细致的西服面料的条纹元素转化为室内设计的一部分，用艺术感的条纹壁纸或地毯装点空间，赋予商务酒店的房间以新鲜的感觉。同时，设计师并没有忽略一家商务酒店所需具备的功能性，而是将其功能与美观完美地结合在一起。

摘要：墨西哥城森本餐厅坐落在市日一家以经典现代设计风格而闻名的酒店内。这个酒店最引人注目的是其生动地运用多变的几何形状以及欢快热烈的配色。为了与这种现代主义风格的酒店保持格调一致而又具有独特个性，设计师在餐厅的每处细节上都呈现了现代艺术的美瘟，无论是定制的家具，抑或是整个空间的所有固定式的器具。